Iranian Journal of

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Background: Diabetes is one of the most common diseases of the body's endocrine system, Based on present forecasts of its prevalence will increase in human societies. Diabetes mellitus consists of 5 groups, its two major groups: type I diabetes or insulin-dependent and type II diabetes or non-insulin dependent diabetes. The aim of this study was to evaluate the effect of alcoholic extract of green wheat leaves on glucose, cholesterol, triglycerides, LDL, HDL and total antioxidant capacity of blood serum in alloxan-induced diabetic mice.
Methods: In this study, 40 male mice with an average weight of 25-20 grams in eight groups of five rats: The negative control, positive control (sham), Methformin (60mg/kg), green Wheat leaf extract (100, 200, 400, 800 and 1000mg/kg) were tested. Blood glucose was measured at baseline, then in the positive control group and the experimental groups by Alloxan (120mg/kg) Diabetes was induced by intraperitoneally. During the study, the positive control group and experimental groups received aforementioned compounds for 10 days via intraperitoneally and after 48 hours of each group blood samples were taken through the intraventricular anesthesia and glucose, cholesterol, triglycerides, LDL, HDL and total antioxidant capacity in serum were measured. Quantitative results achieved in this research by one-way ANOVA and Tukey post hoc test between the groups studied Considering the significance level of p <% 5 were analyzed.
Results: The results showed that blood glucose changes in green Wheat leaf extract and metformin groups compared with the positive control group and negative control group was significant at the 5% level and In all under study groups blood glucose levels, Compared with the positive control group decreased and is close to the negative control group also in doses of 100, 200, 800 and 1000 mg/kg Reduced blood glucose is better than methformin group. Methformin and green Wheat leaf extract caused a significant increase at all doses studied in the TAC's Blood. Methformin and green Wheat leaf extract on the amounts of LDL, HDL and cholesterol in diabetic groups had no significant effect and did not have significant difference with other groups. There was no significant effect of different doses of green Wheat leaf extract on the blood triglycerides. However, metformin has a significant impact on triglyceride levels.
Conclusion: The results of the effects of green Wheat leaf extract on glucose and serum antioxidant capacity
It can be noted that these extracts in the treatment of diabetes and reduce its complications can be considered as an option.
 

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Background: Increasing blood glucose levels is associated with a reduction in the antioxidant defense of the body. The purpose of this study was to compare the effect of aerobic resistance exercises with and without ginger on some of the oxidative and antioxidant indices in type 2 diabetic women.
Methods: Twenty-two type 2 diabetic women with a mean age of 49.47±4.36 years, BMI 31.3±16.3 kg / m2, height 0.56±0.04 meters were selected randomly and they were divided into two experimental and control groups. Both groups performed 12 weeks, 3 sessions per week, exercises with intensity of 75-85%, 1RM in 8 stations, and after 5 minutes of rest, aerobic training exercises with an intensity of 75-85% of MHR. A daily group of 800 mg capsules of ginger rhizome powder and the other group consumed capsules containing wheat flour. 24 hours before and after training, MDA, TAC, SOD, GSH, HbAlc, glucose and insulin and body composition were measured.
Results: 12 weeks of combination exercise caused a significant decrease in glycosylated hemoglobin, insulin resistance, insulin resistance, lipid percentage, and a significant increase in TAC and GSH compared to baseline (P <0.05), while SOD and MDA Did not have any significant effect.
Conclusion: Combined exercise with and without zinc seems to improve antioxidant and some of the body composition indices in type 2 diabetic women.