Sima Zahedi, Ali Darvishpoor Kakhaki, Meimanat Hosseini, Zahra Razzaghi,
Volume 17, Issue 4 (5-2018)
Abstract
Background: Hemodialysis is the most common treatment in patients with end stage of renal disease (ESRD). Patients undergoing hemodialysis due to multiple drug treatments, special food programs and being able to cope with their illness need to self-care activities. Due to lack of information about the role of health literacy in effectiveness of self-care in these patients, this research aimed to determine the correlation between self-care and health literacy in patients undergoing hemodialysis in Valiasr Hospital of Arak in 2015.
Methods: In this descriptive correlational study, 93 undergoing hemodialysis patients selected by objective sampling method. Data collecting instruments were "demographic questionnaire", "self-care questionnaire " and "Health Literacy for Iranian Adults questionnaire". The content and face validity of questionnaires was assessed. Reliability assessed through internal consistency (Cronbach's alpha) and Intra- Class Correlation Coefficient. Data were analyzed by SPSS, version 21, using, Kolmogorov–Smirnov test, Descriptive Statistics and Kolmogorov–Smirnov test.
Results: The results showed that 79/6% of patients were male and 20/4% were female with an average age of 54/18 ± 13/9 year. The mean score of self-care and health literacy were 146/90± 45/46, 88/14± 36/42 and were at a moderate level. The lowest score of self-care and health education related to the field of fluid intake and decision-making and behavior. There was a significant positive correlation between self-care and health literacy (p<0/0001, r= 0/6).
Conclusion: The existence of a significant positive correlation between self-care and health literacy showed that the hospital managers and the nurses must pay more attention to what patients undergoing hemodialysis need. Considering the importance of health literacy in the care of patients undergoing hemodialysis, it seems necessary to nursing administrators and Politicians use educational programs tailored to the patient's health literacy level in order to promote their health and quality of life.
. Zahra Goli, Dr Farzaneh Taghian, Dr Khosro Jalali,
Volume 24, Issue 5 (12-2023)
Abstract
Introduction:The purpose of the research was to compare the effect of two types of raeobic exercise with and without incline on the modulation of oxidative stress and kidney function in CKD mice.Methods:The number of 24 two-month-old C57bl6 female mice weighing 25±26.1 grams were randomly divided into four groups:healthy control,CKD-affected mice,CKD and aerobic exercise without incline and CKD and aerobic exercise with incline were divided. In order to induce CKD,they received adenine powder of 0.2% mg/kg for 4 weeks.The training groups performed eight weeks of treadmill training(5 sessions perweek)one group performed with a 20-degree incline and the other group performed with a zero-degree incline.After the last training session, sampling of blood was done to measure blood urea nitrogen and urea and glutathione concentration by ELISA method.The expression of SIRT1,NRF1 and TNF-α genes was measured by qPCR-Real Time technique. For statistical analysis,one way ANOVA test and Tukey's post hoc test and significance level P≤0.05 were used.Findings:The results showed that induction of CKD caused a significant increase in blood urea nitrogen and a significant decrease in glutathione concentration compared to the healthy control group (P<0.05).On the other hand, in the exercise group, there is a significant increase in glutathione concentration and a significant decrease in blood urea nitrogen (P<0.05).The expression level of SIRT1 and NRF1 in the slope training group increased significantly and the expression level of TNF-α decreased significantly (P<0.05).
