Showing 6 results for Herbal
Anu Chandra, Abbas Ali Mahdi, Wajih Rizvi, R.k. Singh, Sohail Ahmad, L.c. Mishra,
Volume 4, Issue 1 (7-2004)
Abstract
Background: up to know many herbal medicines with different oral formulations have been recommended for diabetes. The aim of this study was to investigate the effect of 4 herbal hypoglycemic agents include garlic (Allium sativum) neem (Azadirachta indica), tulsi (Ocimum sanctum) and bitter gourd (Momordica charantia) on blood glucose, antioxidant enzymes and metal ions in diabetics
Methods: Crude extracts of herbal agents was prepared and each one was given to one group of diabetic rats. Two group of diabetic rats received insulin and glibenclamide. As controls, two groups of healthy and diabetic rats received saline. Body weight, fasting blood glucose, antioxidant enzymes and metal ions were measured before and after the study.
Results: All agents including herbal preparations, insulin and glibenclamide reduced the levels of blood sugar and lipid peroxide when compared with diabetic control. These agents also increased levels of antioxidant enzymes in diabetic rats. Antioxidant enzymes decreased significantly in diabetic controls. Metal ions increased in diabetic rats treated with herbal agents, insulin and glibenclamide but decreased in diabetic controls.
Conclusion: Above mentioned herbal plants may be useful in the treatment of diabetes as they not only have hypoglycemic effect but they also protect rats from free radical mediated cellular injury by improving the activity of antioxidant enzymes. They also improve the levels of metal ions which are associated with antioxidant enzymes.
Najmabadi Shahandokht , Marzieh Nojomi , Maziar Moradilakeh, Hassan Shojaie Baghini,
Volume 13, Issue 5 (7-2014)
Abstract
Background: The increasing prevalence of Diabetes mellitus as a chronic disease, and as a manageable disease with medical nutrition therapy, needs to consider and determine the self-care diet therapy The aims of this study to determine the prevalence of self-medication, self control in diet therapy and use of medicinal herbs, for diabetes control.
Methods: 502 Diabetic Patients were selected randomly in this descriptive, cross sectional study, from 4 diabetic clinics from urban Primary health care Center, and diabetic clinic in Endocrinology and Metabolism Research Institute. Data were collected via face to face structured interview of respondents by Dietitian experts, in the clinics using a developed and piloted questionnaire.
Results: 83.8% respondents were Type 2 Diabetics patients, 70.3% were controlled using oral medicines and diet therapy, and herbal medicine .The more common herbal medicine use for diabetes control were Cinnamomum zeylanicum(Cinnamon) 34.1%, Tigonella foenum graecum 13.7%, Allium sativum 28.6%, Anethum graveolens 28.8%, Zingiber officinal 17.8% .There was significant association between education level, age, and morbidly of other chronic diseases and self herb medication.
Conclusion: Use of nutritional herbs, effective in reduction blood sugar and lipids profile were most common self herbal medication in diabetic patients. Which are The prevalence of self-medication with carbohydrates limited diet and herbal medication, were the most diabetes control methods in the respondents patients in this survey.
Zahra Abbasizadeh, Mahnaz Kesmati, Hamid Galehdari, Anahita Rezaie, Seyed Mansor Seyednezhad,
Volume 14, Issue 6 (9-2015)
Abstract
Background: The process of wound healing is impaired in diabetes. Many efforts have been made to accelerate the wound healing process. Long time healing effect of a herbal complex containing Aloe vera, Myrrh, dragon’s blood and henna has been observed in wound healing, But sufficient scientific evidence of how the mechanism of action of this compound is absent in diabetic wounds Whereas the effect of each of them separately in several studies on ulcers observed. The purpose of this study was to evaluate the effect of topical herbal (briefly called Herbalin) on wound healing in diabetic rats.
Methods: The diabetic rats were divided into two groups: control (treated with Vaseline as a vehicle) and experimental (treatment with herbalin) were included. In each class, all wound round with a diameter of2cmwas made on the dorsal surface of diabetic rats. Wound measurement and histopathological parameters such as the formation of re-epithelization, granulation tissue formation and the average thickness of the epithelium at intervals of7, 14and21dayswere evaluated. Strain epithelium on day 14andthe wound length atday21was evaluated in the terminal phase.
Results: In macroscopic study, the Herbalin treated wounds were found to healing much faster and the day 14 has considerable change compared with control group (P<0.05). In microscopic study, in all cases of the Herbalin treatment groups showed a significantly increased as compared with controls (P<0.05).
Conclusion: According to the results, the herbal complex, possibly by accelerating the formation of granulation tissue and epithelium and thickening of the epithelium has an important role in wound healing in diabetic and reduces the time required for healing.
Ameneh Marzban, Mehran Barzegaran, Samaneh Delavari, Hadi Marzban, Vahid Rahmanian,
Volume 17, Issue 6 (10-2018)
Abstract
consumption of medicinal plants, especially when conventional treatments are not able to control diabetes, and the patient needs insulin administration, is remarkable. The aim of this paper is the attitude and social behaviors of Bandar Abbas 's people to consume of herbal medicine in treatment of DM.
Methods: This descriptive cross-sectional study was conducted in 2017. In this study, 300 individuals aged 20 to 65 years were selected randomly from 10 locations in Bandar Abbas. The research instrument was a two-part questionnaire that evaluated demographic information and attitude. Data were analyzed by SPSS-24 software using descriptive statistics (mean, standard deviation and frequency), ANOVA, T-test Independent and Chi-Square tests.
Results: The mean and standard deviation of people's attitude toward using herbal drugs in the treatment of diabetes was 47.15±3.23. The mean score of attitude with gender variables (P = 0.002), age (P = 0.04) and education (P = 0.02) was statistically significant. The majority of people had their information on herbal medicines through their parents and relatives, and this difference was statistically significant in distributing the frequency of information sources in individuals. (P = 0.001)
Conclusion: According to the results of this research, people's attitude towards the use of herbal medicines in the treatment of diabetes was at a relatively good level, which can play a constructive role in the scientific and executive planning of the health and medical professions.
Batool Yamani Ardakani, Maliehe Mobarakian, Vali Bahrevar, Moradali Zareipour, Sadegh Kazemi, Mojtaba Fattahi Ardakani,
Volume 24, Issue 2 (6-2024)
Abstract
Background: Despite the increased use of complementary medicine by diabetic patients, there is no clear estimation of complementary and herbal medicine use by these patients in Iran. This study was conducted to investigate the uses of herbal medicine among patients with type II diabetes in Yazd, Iran, in 2022.
Methods: A cross-sectional study was carried out on 633 patients with type II diabetes referred to the Diabetes Research Center in Yazd City from June to September 2022. A questionnaire-based theory of planned behavior developed and validated by the researcher was used for data collection. In addition to demographics and disease-related information, the instrument included questions about using herbal medicine used. Descriptive statistics, Chi-square, Fisher's exact, and linear regression tests were used to analyze the data.
Results: The most common herb used was cinnamon (34.7%). The majority of patients used herbs daily (56.9%). Using herbal medicine was significantly associated with Attitude (r= 0.48, p< 0.001) Subjective norm (r= 0.39, p< 0.001), perceived behavior control (r= 0.38, p< 0.001) and intention (r= 0.4, p< 0.001). Constructs of the theory of planned behavior 73% predicted intention to use herbal medicine. Subjective norm structure had the highest predictive power of intention to consume herbal medicine (ß= 0.49, p< 0.001).
Conclusion: Subjective norm is the most predictor of intention to use Herbal medicines in patients with diabetes. Therefore, it is very important to pay attention to the beliefs, customs, and culture of the surrounding community in the correct self-management of disease control and the use of effective drug control.
Dr Alireza Moumivand, Dr Bahareh Tavakoli-Far, Dr Gelareh Vahabzadeh, Dr Saeideh Momtaz, Dr Maliheh Farid, Dr Hosein Hosein Rafiemanesh, Dr Mahdi Goudarzvand,
Volume 24, Issue 5 (12-2023)
Abstract
Introduction: Diabetes is one of the most common disorders of the endocrine glands, the main characteristic of which is an increase in the concentration of glucose in the serum of patients. Herbal medicines are widely accepted by people due to less side effects. The purpose of this study is to investigate the protective effect of the silybum marianum, melissa officinalis, vaccinium arctostaphylos, trigonella foenum, urtica dioica and citrullus colocynthis extracts mixtures in the PC12 cell model in a high glucose environment.
Methods and Methods: After 24, 48, and 72 hours of adding different concentrations of plant extracts (silybum marianum, melissa officinalis, vaccinium arctostaphylos, trigonella foenum, urtica dioica and citrullus colocynthis) in the normal culture medium of PC12 cells and the medium with high glucose (25 mg/ml, 13/5), cell viability was measured by MTT method.
Results: The results showed that the viability of PC12 cells did not change in 24, 48 and 72 hours after treatment with a mixture of plant extracts. The survival rate of cells in the high dose glucose group was significantly reduced compared to the control group, and the mixture of plant extracts in high doses significantly reduced cell death in these conditions.
Conclusion: Based on the available findings, glucose with a concentration of 25, 13.5 mg/ml caused the death of PC12 cells and the mixture of plant extracts was able to reduce the cell death caused by high glucose in all three times 24, 48 and 72 hours after exposure with nerve cells.
