Showing 22 results for Iran
Bagher Larejani, Farzaneh Zahedi,
Volume 1, Issue 1 (7-2001)
Abstract
Diabetes mellitus is a common disease and its incidence and prevalence are increasing in most populations. The trend is particularly worrying in developing countries. The number of diabetic patients in Iran is estimated at 1.5 million. The distribution of diabetes in Iran has been the subject of several surveys. Disease prevalence rates, for all forms of diabetes, of 7–17% have been variously reported in several adult urban populations. Geographical prevalence is not uniform, however, and the prevalence of type 2 diabetes mellitus has been reported at 3-5% in rural communities. A screening program conducted at different locations of Iran revealed that nearly 50% of people with type 2 diabetes were unaware of their condition. Not surprisingly, therefore, that the incidence of complications for diabetes is high in Iran. A battle is being waged on all fronts at present to control the socio-economic scourge that is diabetes mellitus. A national program has been designed for the primary, secondary, and tertiary prevention of diabetes. The major strategies that it puts forwards are screening, the identification of high-risk groups, public education, and the training of specialist care providers. This article reviews the epidemiological features of diabetes in Iran.
Mahdi Zamani, Mohammad Amin Tabatabaiefar, Arezoo Savabi Esfahani, Fereidoon Mostafavi, Arya Sotoudeh, Bagher Larijani,
Volume 4, Issue 4 (6-2005)
Abstract
Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cell mediated selective pancreatic β- cell destruction occurs. Half the risk of T1DM development is given by the HLA gene region while the remaining risk is assigned to non-HLA genes , probably those engaged in the formation of antigen interaction complex. The CD4 gene product, which is among the most prominent T-cell surface receptors with a key role in antigen processing, could be regarded as a strong candidate.
Methods: We investigated the possible association of the CD4 gene polymorphism with T1DM using the candidate gene approach. The pyrimidine- rich pentanucleotide repeat polymorphism residing in the promoter region of the CD4 gene was studied. In the present study 92 Iranian T1DM patients and 108 healthy matched control individuals were screened by PCR technique.
Results: The analysis of our results shows the protective association of CD4*A3 (RR= 0.159, 95% CI: 0.036-0.707 Pc=0.025) and the susceptible role of CD4*A5 (RR= 7.379, 95% CI: 1.630-33.414 Pc=0.010) with T1DM.
Conclusion: Our results suggest that the certain CD4 alleles are associated either negatively or positively with T1DM in the Iranian population.
Heydar Shadi,
Volume 5, Issue 0 (10-2005)
Abstract
The history of Medical ethics is as longer as the history of the medicine. In medical literature of all great civilizations such as Greek, Babylon, Egypt, Indian, Christian and Islamic, is full of ethical codes and oaths. Nevertheless the medical ethics as an academic filed appeared in 1960s. This article is a short review of medical ethics history in ancient, medieval and modern periods. In introduction after defining medical ethics and clarifying its relation to similar fields such as bioethics and clinical ethics we have explained the reasons of medical ethics emergence. In the next three parts "ancient period", "medieval period" and "modern period" the development of medical ethics was explained from initial societies to ancient Greek, Indian, Christian, and Islamic civilization to modern period. In the last part the recent developments of medical ethics in Iranian society has been reported.
Hossein Fakhrzadeh, Maryam Ghodsi, Anahita Hamidi, Alireza Moayyeri, Ramin Heshmat, Rasool Poorebrahim, Masoumeh Noori, Bagher Larijani,
Volume 5, Issue 1 (8-2005)
Abstract
Background: It is well recognized that an increased body weight is often associated with increased blood pressure. Moreover, leptin an adipocyte-derived hormone is strongly suggested to have an important role in pathogenesis of the obesity. We aimed to evaluate the levels of serum leptin in association with obesity and hypertension in a sample of Iranian obese children.
Methods: Children from all the primary schools of a distinct of Tehran were screened for obesity. Children with a waist circumference equal to or above 90th percentile for their age and height were invited for the study. Anthropometric measurements were done and blood samples for fasting serum leptin levels were collected from 563 enrolled obese children. Multivariate linear regression analysis was used to evaluate relationship of various factors with obesity.
Results: Mean Serum leptin levels were 8.65 ±2.18 (ng/ml). Serum Leptin levels were higher in girls than boys (P=0.009). There were significant correlations between body mass index (BMI) and serum Leptin levels, child age, systolic and diastolic blood pressure. Systolic blood pressure and diastolic blood pressure lost their association with serum Leptin level in multivariate linear regression analysis.
Conclusion: BMI is independently associated with Leptin levels among obese children. This may affirm a role for this hormone in the pathogenesis of childhood obesity. It seems unlikely that plasma Leptin be a major mediator of association between obesity and hypertension. However, severe hyperleptinemia may act as a risk factor for increased blood pressure.
Bagher Larijani, Farzaneh Zahedi,
Volume 5, Issue 4 (6-2006)
Abstract
Medicine and ethics have increasingly more links caused by considerable progresses in biotechnology in different fields of medical diagnosis, treatment and prevention. The issue of research ethics is one of the most important subjects which have been emphasized by international and regional organizations, policy-makers, medical and religious professions, scientists and researchers in different countries in recent decade. It is widely understood that research ethics committees typically play an important role in evaluating the ethical aspects of medical research. A ‘Research Ethics Committee’ (REC) is defined as a multidisciplinary, independent, body charged with reviewing research involving human participants to ensure that their dignity, rights and welfare are protected. Research ethics committees protect the welfare and rights of participants involved in research through reviewing research proposals, monitoring the conduct of research and dealing with complaints that arise from research.
This manuscript will introduce you to the concepts underlying research ethics committees worldwide and in Iran. This paper will begin with a brief history of research ethics, continues with a concise overview of ethics committee situation and responsibilities, and ends with an outline of the national activities. We hope the manuscript could enhance awareness of biomedical researchers about status and duties of research ethics committees and consequently strengthen the RECs in our country.
Bagher Larijani, Farzaneh Zahedi, Seyed Hassan Emami Razavi,
Volume 6, Issue 2 (9-2006)
Abstract
Medical ethics has a long history worldwide, and the move towards a trans-cultural ethics must be based on an appreciation of the civilizations’ history. It is often thought that medical ethics history has begun by Hippocrates, however it is much older. It is clear that various cultures such as Babylonia, ancient Egypt, Greece, and the Persians have attempted to regulate medicine and to protect patients' rights in the known ancient world. One of the earliest written provisions in this field, which comes back to about 1750 BC, is the code of Hammurabi written by Babylonian.
In this paper we aimed to explore the roots of medical ethics in Persian history, particularly, after adherence of Iranians to Islam. In this article, we used related books of great Iranian and non-Iranian historians, and examined some authentic articles collected through searches of databases such as Medline and Ovid and search engines such as Google Scholar.
History of medicine in Iran has begun about fourth century BCE. Great Iranian physicians had paid special attention to ethics in their practices, teachings and manuscripts. There was a gap between the ancient civilizations and the Renaissance era in Europe, commonly called the dark ages (Medieval). The immense strides have been made by the Persians in that long interval which is briefly reviewed.
Sommayeh Rashid Shomali, Vahideh Montazeri, Seyed Mohammad Akrami, Ramin Heshmat, Bagher Larijani,
Volume 7, Issue 1 (7-2007)
Abstract
Background: High prevalence of consanguineous marriages has been reported in Iran. Since this pattern of marriage may increase the prevalence of diseases with autosomal recessive pattern of expression, the study was assigned to determine this among patients referred to diabetes and osteoporosis clinics of Dr Shariati hospital, Tehran, Iran.
Methods: The consanguineous marriage was studied among 1789 couples of three successive generations via Questionnaire.
Results: The prevalence of consanguineous marriages in three successive generations was 9%, 17% and 19%, respectively with an increasing pattern of prevalence. Overall the prevalence of first cousins marriage was 10% with 69% among consanguineous marriage group. The higher the level of education, the lower the prevalence of consanguineous marriage.
Conclusion: In view of the increasing prevalence of consanguineous marriage that may be followed by some trouble consequences about disease expression, it seems necessary to provide facilities for genetic counseling before marriage for youth.
Baharak Najafi, Seyed Masoud Arzaghi, Hossein Fakhrzadeh, Farshad Sharifi, Shervan Shoaei, Mahtab Alizadeh, Mohsen Asadi Lari, Reza Fadayevatan, Neda Mehrdad,
Volume 13, Issue 1 (1-2014)
Abstract
Introduction: Mental disorders are common in the elderly.The purpose of this study was to assess the
general health status and its related factors among people ≥ 65 years in different districts of Tehran.
Methods: This study has used data of the participants ≥ 65 years old in urban health equity and response
tool (Urban-HEART) study. Finally the data of 1313 elderly were considered for this study. Variables
included demographic characteristics (gender, age, education level, family size, marital status and
employment status) and mental health using the Persian GHQ -28 questionnaire (domains: somatic,
depression, insomnia and anxiety) and quality of life using the SF12.
Results: The mean age of participants was 73.68 (5.91) (women=627 and men=686). GHQ-28 median of
scores the participants were 24.00 (22.00)[20.00 (27.00) in women and 19.00 (19.00) in men
(P<0.01)].Based on GHQ-28 cut-point 23, 50.2%of the participants had mental health problems, [61.2%
women and 40.1% men (P<0.01)].The residents of third municipality districts had the best mental health
(26.3% of men and 38.5% of women had mental health problems) and the aged of 20th municipality
district had the worst health status (65.7% of males and 84.2% of women had mental health problems).In
multivariable logistic regression model, for each year of increment age, 2.9% chance of mental health
problems increased (P<0.01). With increasing level of education, mental health status was improved (P
trend < 0.01). The relationship between family size and mental health was not significant (P =0.06).
Conclusion: Mental health status of the elderly in Tehran was worse than the many other countries. The
elderly lived in 20th
municipal district, had the worst and the dwellers in the 3th
district had the best mental
health status.
Reza Safdari, Mahtab Alizadeh, Maryam Mohamadiazar , Farshad Sharifi, Hossein Fakhrzadeh,
Volume 13, Issue 6 (9-2014)
Abstract
Background: Reducing in mortality rate due to improved health status in recent years has led to an
increased number of elderly people in the world. Therefore, this study aimed to determine the structure
of the home care plane in developed countries to provide practical implementations for Iran. This
paper is based on valid studies, library and internet searches in databases like science directly,
Springer, Proquest, and advanced search in Google to review the literature on the home care programs
in developed countries.
Results: Documents showed that developed countries have established the aimed, needs, priorities
programming of the elderly home care plan. Those groups of countries have designed the home care
services to care of older people in their homes respect to maintained of their function and ability as
independent individuals.
Conclusion: The investigations have been shown that community-based services and home care
programs that is not considered as a medical service component, could be eliminated the support
needs, and helped the elderly people to live independently and continue their life with quality.
Considering the significant role of home services in the prevention of hospital readmission in elderly
and to maintain of independency rate and also increasing the quality of life in elderly people, is a
necessary issue in Iran that makes to improve on the quality of life in Iranian seniors
Baharak Najafi, Fariborz Bakhtiyari, Azar Manavi, Mohammad Reza Soufinejad, Hossein Fakhrzadeh, Seyed Masoud Arzaghi, Mahtab Alizadeh, Neda Nazari, Shervan Shoaee, Farshad Sharifi,
Volume 13, Issue 6 (9-2014)
Abstract
Background: Because of various health problems, the risk of the death in the elderly is higher than adults. The purpose of this study was to investigate the causes of the death, and comparing the cause of death that recorded on the death certificates and those were extracted from the medical records review.
Methods: Variables included the demographic characteristics (age and sex), time of death and the cause of death were recorded in the death certifies and those were extracted from the medical records.
Results: The mean of death age was 83.8 (8.50) years and in women and men were 84.2 and 81.5 years, respectively, (P < 0.01).The most prevalent cause of death was sudden cardiac death based on both death certificates recorded and review of medical records were 42.5% and 25.9% respectively. Sudden cardiac death in both methods was higher in women than men. Using the kappa, the highest degree of correspondence about the cause of death between two method was about gastrointestinal bleeding (K = 0.76) and then the cancers (K = 0.71) and respiratory infections (K =0.67). Total Kappa of two methods for causes of mortality was 0.50. The most cases of death were reported during 12:00 – 13:59 and 8:00 – 9:59am, time period (16.2 % and 14.1% respectively).
Conclusion: the causes of deaths, which are recorded in the elderly nursing homes, do not have enough accuracy. Due to the high incidence of sudden cardiac death in elderly in nursing homes, resuscitation facilities and teams may be helping to reduce these types of death.
Fariborz Bakhtiyari, Mahshid Foroughan, Hossein Fakhrzadeh, Neda Nazari, Baharak Najafi, Mahtab Alizadeh, Seyed Masoud Arzaghi, Farshad Sharifi, Shervan Shoaee, Qorbani Mostafa ,
Volume 13, Issue 6 (9-2014)
Abstract
Background: One of the common problems of the elderly, which increase of its prevalence with aging is the dementia and the cognitive impairment. We can help the involved patients to have a better quality of life with early diagnosis of the cognitive impairment. The aim of this study was an assessment of the validity and reliability of the Persian version of the abbreviated mental test (AMT) among the older people in a nursing home setting.
Methods: 176 eligible elderly people aged ≥ 60 years living in KahrizakCharity Foundation (KCF), were selected randomly based on medical record number. Demographic information and past medical history of the participants were collected. Geriatric depression scale 15 (GDS-15), global deterioration scale (GDS) forms and also the Persian version of the abbreviated mental test (AMT) were administered. The participants were assigned to two groups the normal and impaired cognitive groups, based on DSM-IV diagnostic criteria. The GDS cut-points were used for assessment of validity, sensitivity and specificity of the Persian version of AMT.
Results: The mean age of the participants was 77.30 (7.94) years. The Persian version of AMT had good discriminated validity in diagnosis of normal and impaired cognitive participants (7.35 ± 2.33 and 5.99 ± 2.29, P < 0.01 respectively) and at cut-point AMT< 8,(based on GDS cut-point) it had a sensitivity and specificity 92.15 % and 81.50% respectively. The sensitivity and specificity based on theism IVcriteriawere 64.9% and 64.0% at cut-off point equal to 7, respectively. The internal consistency of the Persian version of AMT was acceptable (Cronbach’salpha coefficient =0. 76). As well as the external reliability (intra-rater) of this instrument was good inter-class correlation coefficient (ICC) = 0.89)
Conclusion: The Persian version of the AMT has appropriate validity and reliability in Iranian older people.
, , , , , , , ,
Volume 13, Issue 6 (9-2014)
Abstract
Background: The world population is aging and it is expected that in 2020 more than one billion people in the world be elderly. The aim of this study was the evaluation of socioeconomic and physical health of elderly people in Ilam province in 2011.
Methods: This study was a cross - sectional study in which 1012 elderly people residing in the city of Ilam and eight townships participated by proportional allocation methods. Data collected by using a standard questionnaire and the Data were analyzed by using SPSS statistical software.
Results: The mean age of the study population was 70/1 ± 8/02 years. The differences between employment status and job type of elderly in each township was Significant. Mean systolic and diastolic blood pressure in subjects was 133/03±28/38 and 11/76±8/02 excursively, and mean body of BMI was 25/72±4/48. 36/1% of the elderly had a history of heart disease, 15% are living with diabetes, and 22/5% had respiratory problems. 45/3% have surgery history, 72/8% experienced joint pain, 64/6% experienced musculoskeletal pain and 12/6% had a history of stroke. 23/8% had problems of knowing the time, 22/8% had problems recognizing the place, 22/2% had problems recognizing people and 25/9 % Shake hands and head.
Conclusion: Common problems with physical health problems reported by elderly of Ilam the same in the rest of the country and major differences in socioeconomic status. Due to lower per capita income in Islam compared to other provinces of Iran, the health status of the elderly has been lowered in Ilam rather to another province.
, , , , , , , , ,
Volume 13, Issue 6 (9-2014)
Abstract
Background: Oral health is an important issue in elders’ life in both food consumption style and their self-esteem. The aim of this study was to survey the oral health among aged people in Gorgan city.
Methods: In a cross sectional study and through a standard questionnaire, the data of 869 aged people who were resident in the areas where were covered by 4th and 5th Health Station of Gorgan Health Center, has been analyzed. Participants (over 60 years old persons) entered in the study through a census method are asked about their oral health by trained persons. Data analyzed by descriptive statistics and Chi-Square test. Alpha level set at 0.05.
Results: Complete toothless was 54.3 percent in male and 62.6 percent in female. Totally teeth preservation rate was 6.4 percent in male and 1.5 percent in female. The mean and standard deviation of tooth loss were 22.5±12.4 in male and 24.4±11.2 in female. The Complete toothless significantly was high in single people compared with married one. Completely toothless was low among aged people with less than or equal to four children and was low among aged people in the worst status of economic situation.
Conclusion: Oral health among the study population was in a bad situation. For preservation of teeth till adult age, appropriate planning and interventions is necessary.
Maryam Sadat Daneshpour, Bahareh Sedaghatikhayat, Mehdi Hedayati, Fereidoun Azizi,
Volume 14, Issue 4 (5-2015)
Abstract
Background: The prevalence of non-communicable disorders such as metabolic syndrome (MetS) is high in developing countries. Metabolic syndrome is a disorder of energy utilization and storage, diagnosed by a co-occurrence of three out of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density cholesterol (HDL) levels. The present review aims to discover the genetic variant reported in association with MetS. Methods: The database for genotypes and phenotypes (dbGaP) and the database for genetic associations and human genome (HuGE navigator) were utilized in order to search for genes and their corresponding polymorphisms related to MetS. Additionally, an electronic literature search for other Iranian studies and the genetic aspect of TLGS was completed using PubMed. Results: For phenotype selection in PheGenI, 30 traits were chosen and after the analysis, 21 of them were in common results with MetS. After finding the common variation between traits and MetS, omitting the repeated SNPs, 173 variations were remained. Finally, results distinguished six of the most important genetic regions found to have strong association with MetS. Conclusion: Identifying major genes that are responsible for the metabolic syndrome may improve the medical care for treating individuals with metabolic syndrome, and eventually may lead to personalized medicine in which treatment is tailored genetically to the patient’s needs. The present candidate regions is a respectable start to replicate genetic studies in large affected Iranian individual which we hope leads us to improve our medical care in this field.
Habibeh Taghavi Kojidi, Farshad Farzadfar, Niloofar Peykari, Bagher Larijani, Shadi Rahimzadeh, Ehsan Rezaei-Darzi, Sahar Saeedi Moghaddam,
Volume 15, Issue 2 (1-2016)
Abstract
Background: Thyroid cancer is the most common form of endocrine cancer. The age and gender-adjusted incidence of thyroid cancer has increased faster than that of any other malignancy in recent years, with the increased incidence seen in both genders, all ethnic backgrounds and all sizes of thyroid cancer. It appears that the rise in thyroid cancer incidence is not only due to medical surveillance and improved disease detection. In Iran, also scattered studies had been accomplished in different provinces and requirement to more attention and planning for thyroid cancer. Thyroid cancer’s control and prevention requires to the evidence–based strategies in different population groups based on national and provincial comprehensive studies on the prevalence and incidence. Thus we aimed to provide the comprehensive information about thyroid cancer prevalence and trend in national, provincial levels among Iranian population.
Methods: In this study we used some steps respectively to show how thyroid cancer prevalence changes in 1990 to 2010 between different provinces. We aggregate cancer registry data set by province, age categorized, gender and merge with other national covariates that were gathered in Iran. Then, linear regression model and logistic regression model were used to modeling and predicting for other provinces and years.
Results: Mean of thyroid cancer prevalence displayed that prevalence increased with increase in years especially more rapidly from 2002-2010 the prevalence rates were estimated to be (0.0-0.25) and (4.2-13.7) per 100000 in 1990 and 2010 respectively and increased in both females and males. Female to male ratio was 2.5. Highest prevalence thyroid cancer were in four provinces of Iran, Isfahan (mean rate 4.3 per 100000), Yazd (mean rate 4.1 per 100000), Tehran (mean rate 4 per 100000) and Qazvin (mean rate 3.1 per 100000) respectively.
Conclusion: Iran map displayed with increase in years, thyroid cancer prevalence become larger. Additional research on the risk factors for thyroid cancer is needed to explain the difference of thyroid cancer prevalence between provinces.
Zeinab Alizade, Leila Azadbakht,
Volume 15, Issue 3 (2-2016)
Abstract
Background: The clustering of cardiovascular risk factors , known as the metabolic syndrome , greatly increases the risk of developing diabetes and cardiovascular disease .individuals with the metabolic syndrome are also at increased risk for premature death from cardiovascular disease or all–cause mortality . Although is a particular importance, its epidemiology in Iran has not been studied systematically. Aim of this review of published data was to describe epidemiology of metabolic syndrome in Iran.
Methods: We searched MEDLINE, sid, magiran, iranmedex, and irandoc databases through 2014, and examined the reference lists of pertinent articles, limited to studies in humans.
Results: Total 45 studies were eligible (25 English and 20 Farsi). The findings show the high prevalence of metabolic syndrome in both sexes according to three criteria. The prevalence of metabolic syndrome was more in women than men. We found that differences in screening programs and diagnostic criteria or various ethnic groups make it difficult to compare frequencies of metabolic syndrome among various populations. Nevertheless, factors that increase risk of metabolic syndrome were age, sex, body mass index, low HDL and high triglyceride.
Conclusion: High prevalence of metabolic syndrome and relevant risk factors suggest the identification of the risk factors should be attempted to prevent syndrome acquisition.
Kourosh Sayehmiri, Abbass Sheykhi, Forghan Rabiei Fakhr , Alireza Yadegarazadi, Milad Azami,
Volume 15, Issue 4 (5-2016)
Abstract
Background: Patients with type 2 diabetes mellitus are more prone to depression. Prevalence of depression in the Iranian results of studies is different. Therefore, the present study aims to study the prevalence of depression in Iranian patients with type II diabetes mellitus.
Methods: This study is a systematic review based on PRISMA guideline for systematic reviews and meta-analyses study. Literature searches of, Scopus, MEDLINE, PubMed, Science Direct, Cochrane, EMBASE, Web of Science, Springer, Online Library Wiley, Google Scholar search engine and Iranians database for publications in Persian and English were conducted up to December 2015. Searches were performed by two researchers independently using standard keywords. Reviewers extracted data and assessed methodological quality in duplicate. Meta-analysis was performed using STATA, version 11.1 to combine data through Random Effects Model.
Results: Sixteen studies and 3,284 subjects with a mean age of 48.6 years were included in the analysis. The prevalence of depression in Iranian patients with type II diabetes was estimated 54.8% (95% CI: 43.5- 66.1). This range for males and females were calculated 32.2 %( 95% CI: 16.3-48.1) and 60% (95% CI: 46.4-73.7), respectively. The highest prevalence of depression was in the center of Iran (60%) and the lowest rate was in the west of Iran (38%).
Conclusion: Regarding to high prevalence of depression in patients with type II diabetes, Implementation of screening program for psychiatric disorders, especially depression as well as conducted psychiatric consultation routinely for diagnosis and treatment of depression in these patients it seems necessary.
Baharak Najafi, Parisa Taheri Tanjani, Farshad Sharifi, Hosein Fakhrzad, Mahtab Alizadeh, Masoud Arzaghi, Mehdi Varmaghani, Mahdi Ebrahimi,
Volume 16, Issue 5 (10-2017)
Abstract
Background: The aging of the population is a great challenge of the public health in this century. The health promotion of the elderly people requires a comprehensive and accurate understanding of their health status.
Methods: This cross-sectional study has assessed the health status of 191 old people ≥ 60 in Sistan and Balouchestan province that selected by a multi-level cluster random sampling. General health data was collected using SF-36 questionnaire, nutrition status was assessed using Mini Nutritional Assessment (MNA), depression status was detected by the geriatric depression scale-15 (GDS-15), functional status was assessed using the activity daily living (ADL) and instrumental activity daily living (IADL) questionnaires, as well as, the information about demographic, history of diseases, vaccination, participation in social activities, and the utilization of elderly care services were evaluated by an approved questionnaire. History of hypertension was asked from the participants. Moreover the blood pressures of them were twice measured.
Results: The mean age of the participants was 69.81 (8.32) years. The health status was reported excellent and bad by 4.2% and 9.4% of the participants, respectively. The prevalence of fall in recent year, memory disorder, hearing and visual impairment, and malnutrition were 35.3%, 15.6%, 30.3%, 56.6%, and 8.9%, respectively. The prevalence of dependency in "activity of daily living" and "instrumental activity of daily living" were 25.8% and 58.2%, respectively.
Conclusion: It seems that the prevalence of malnutrition, impaired ADL and IADL, and memory impairment in the older population of Sistan and Baluchestan are above the national and global averages.
Afshin Mousavi Chalak, Aref Riahi,
Volume 17, Issue 5 (7-2018)
Abstract
Background: Determine of position and role of each country on scientific production in different subject areas shows level of capacity and performance of the country to help and improve this subject area. The aim of this study is to quantitative and qualitative examine of scientific production of Islamic Republic of Iran in the field of Diabetes and determine its regional and international position.
Methods: This is Survey-Descriptive Study and use Scientometrics approach. Statistical populations include 2291 scientific articles and papers which have been published by Iranian authors in the field of Diabetes in Scopus Database during 2 last decades. We used SPSS, NodeXL and VOSviewer to draw graphs and analysis data.
Results: Findings show that Iranian scientific outputs in the field of Diabetes increased from 5 in 1996 to 299 in 2015. Tehran University of Medical Science, United States and Dr Freedom Azizi Respectively founded as the most important producer Center, Partner country and high producer Author. Also place of Islamic Republic of Iran upgraded in the period study and stay on second position in region and twenty first position in the word.
Conclusion: Although Iranian scientific production in the field of Diabetes have been increased in a quantitative factors, but share of the Islamic Republic of Iran among all world production in the field of diabetes was so low. Also most of scientific papers and articles published in internal journals which haven’t good and high quality. Making planning and tacking decision by Medical Universities and Government of Health seems necessary to increase number of researches in diabetes and promote quality and quantity of scientific papers.
Amir Akbari, Hamid Mohebbi, Elma Tabari,
Volume 19, Issue 2 (1-2020)
Abstract
Background: The aim of this study was to investigate the effects of high fat diet-induced obesity and interval and continuous exercise training on visceral fat SIRT1 and insulin resistance in male rats.
Method: Forty male rats were divided into two groups: high-fat diet (HFD; n=32) and standard diet (C; n=8). After 10 weeks inducing obesity, eight rats from the HFD and C groups were sacrificed, and rest of obese rats were randomly divided into three groups: obesity control (OC), moderate intensity continuous training (MICT) and high intensity interval training (HIIT). The HIIT and MICT protocols were performed for 12 weeks and 5 sessions per week. Visceral fat samples were collected to measure protein levels of SIRT1 by western.
Results: Induction of obesity was associated with a significant decrease in visceral fat SIRT1 and an increase in insulin resistance (P˂0.05). In contrast, both HIIT and MICT significantly increased visceral fat SIRT1 protein levels (P˂0.05), whereas HIIT effects were significantly higher (P˂0.05). Also, both HIIT and MICT protocols improved insulin resistance (P˂0.05).
Conclusion: Exercise training is likely to play an important role in regulation of visceral fat SIRT1 and because of that may be effective in improving insulin resistance. The increase in SIRT1 also appears to be dependent on the intensity of exercise training.
