Showing 6 results for Meta-Analysis
Esmat Mosayebi, Maryam Sharifi, Mahgol Tavakoli,
Volume 13, Issue 5 (7-2014)
Abstract
Background: One of the important indicators of diabetes treatment and control is enhancement of quality of life in patients with diabetes. Therefore, in recent years, quality of life in these patients regarded by therapists and researchers and increased studies in this field. The aim of this study was collection and integration of these studies results to investigate the effect size of sport and psychological interventions on quality of life in patients with type 2 diabetes by meta-analysis method.
Methods: For this purpose, 25 acceptable studies (15 psychological interventions, 10 sport interventions) in terms of methodology (hypothesis, research method, statistic population, volume of sample, sampling method, instrument measure & statistic analysis method) selected, and meta-analysis performed on them. Research instrument was checklist of meta-analysis.
Results: The study findings showed that the rate of effect size of psychological interventions on quality of life in patients with type 2 diabetes was d=0.95 (p<0.00001) and the effect size of sport interventions on quality of life in this patients was d=2.2(p<0.00001). According to Cohen’s chart both effect sizes of sport and psychological interventions were high.
Conclusion: psychological and sport interventions can be effective on improvement of quality of life in patient with 2 diabetes.
Masoud Rahmati , Zohreh Ahmadi , Rahim Mirnasoori , Mohammad Fathi ,
Volume 15, Issue 3 (2-2016)
Abstract
Background: In the last few years several polymorphisms variants with significant association to power and sprint performance of elite athletes have been verified. Meantime, the IL-6 gene was introduced as a proper candidate to imply a person alteration into an elite athlete. Therefore, the goal of the present study is to examine the association between IL6 gene polymorphism and power sport using meta-analysis to gather further evidence compared to individual reports.
Methods: Science direct, Google Scholar and Pub Med databases have been searched until March 2015. Articles were studied based on key word IL6 accompanied with polymorphism, mutation, variant and power sport were studied. Statistical software STATA was used to analyze the data.
Results: Ten articles included into the final meta-analysis and Systematic review. The survey of the obtained data from the articles revealed that 292 persons were as an entire group of athletes and 559 people were as a control group. For the allele G vs. C 1.43odds ratio (95% confidence interval: 1.03 -1.99), for the allele GG vs. GC 1.74odds ratio (95% confidence interval: 1.28- 2.36), for the allele GG vs. GC + CC 1.71 odds ratio (95% confidence interval: 1.24 -2.36) and GG + GC vs. CC allele model 0.96 odds (95% confidence interval: 0.77-1.20) was revealed. The relationship between the polymorphism 1800795GG genotype and exercise can be statistically significant (P<0.05).
Conclusion: Generally, the result of the present study indicates that the IL6-174 G/C polymorphism is associated with better performance of elite athletes in power sports. The findings suggest that the genetic profiles might influence human physical performance. Therefore, it is recommended that researcher use IL6-174G/C polymorphism as one of the selected factor for Sports talent.
Kourosh Sayehmiri, Abbass Sheykhi, Forghan Rabiei Fakhr , Alireza Yadegarazadi, Milad Azami,
Volume 15, Issue 4 (5-2016)
Abstract
Background: Patients with type 2 diabetes mellitus are more prone to depression. Prevalence of depression in the Iranian results of studies is different. Therefore, the present study aims to study the prevalence of depression in Iranian patients with type II diabetes mellitus.
Methods: This study is a systematic review based on PRISMA guideline for systematic reviews and meta-analyses study. Literature searches of, Scopus, MEDLINE, PubMed, Science Direct, Cochrane, EMBASE, Web of Science, Springer, Online Library Wiley, Google Scholar search engine and Iranians database for publications in Persian and English were conducted up to December 2015. Searches were performed by two researchers independently using standard keywords. Reviewers extracted data and assessed methodological quality in duplicate. Meta-analysis was performed using STATA, version 11.1 to combine data through Random Effects Model.
Results: Sixteen studies and 3,284 subjects with a mean age of 48.6 years were included in the analysis. The prevalence of depression in Iranian patients with type II diabetes was estimated 54.8% (95% CI: 43.5- 66.1). This range for males and females were calculated 32.2 %( 95% CI: 16.3-48.1) and 60% (95% CI: 46.4-73.7), respectively. The highest prevalence of depression was in the center of Iran (60%) and the lowest rate was in the west of Iran (38%).
Conclusion: Regarding to high prevalence of depression in patients with type II diabetes, Implementation of screening program for psychiatric disorders, especially depression as well as conducted psychiatric consultation routinely for diagnosis and treatment of depression in these patients it seems necessary.
Esmat Mosayebi, Maryam Sharifi, Ahmad Abedi,
Volume 15, Issue 4 (5-2016)
Abstract
Background: Diabetes is a chronic and prevalent disease. In recent years, its prevalence has increased because of lifestyle changes, immobility and subsequent obesity. The increase in diabetes prevalence has provoked multiple and scattered interventions by specialists and health care providers in order to control and regulate blood sugar and its related factors. The purpose of this study was to collect and integrate the results of these interventions in two fields of psychological and sport interventions and to investigate the impact of them on control of Glycosylated haemoglonin (HbA1c) in patients with diabetes by meta-analysis method.
Methods: For this purpose 38 acceptable studies (19 sport interventions and 19 psychological interventions), in terms of methodology, were selected and meta-analysis performed on them. This study is based on 38 effect sizes and research instrument is checklist of meta-analysis.
Results: The study findings showed that the effect size of psychological interventions on control of Glycosylated haemoglonbin is 0.67 (p<0.00001) and the effect size of sport interventions is 0.79 (p<0.00001).
Conclusion: according to Cohen’s chart, the effect size of both psychological and sport intervention on control of Glycosylated haemoglonin in patients with diabetes is medium. However, the effectiveness of sport interventions have been obtained more than the psychological intervention
Nasim Azari, Masoud Rahmati, Mohammad Fathi,
Volume 17, Issue 2 (3-2018)
Abstract
Background: There are many research have been done so far about the effect of exercise training on diabetic type 2 related risk factors. But in this regard there is no study performed in Iran. So, the aim of the present study was to investigate the effect of endurance exercise training on some diabetic type 2 dependent variables in the form of systematic review and meta-analysis of studies that were performed in Iran.
Methods: In this research PubMed, Embase, Cochran, Scopus, ISI, Google Scholar, Science direct, Sid and Magiran databases were searched for Persian sources. Data analysis were done using STATA software version 12.0.
Results: Generally, 242 articles were founded in primary search, which 24 articles were included in this research. Finally research were evaluated 592 Iranian's peoples which 294 peoples as a control group (96 male and 198 women) and 298 peoples as a training group (97 male and 201 women).The results indicate that there were significant association between endurance exercise and blood glucose levels (P=0.0001,-1.016,-0.656;95%CI), insulin (P=0.0001,-1.042,-0.682;95%CI), insulin resistance (P=0.0001;-0.563,-0.217;95%CI).
Conclusion: Generally, this systematic review and meta-analysis study was demonstrated endurance exercise could be related with decrease diabetes type 2 related risk factors. So, it is recommended that sport and medicine experts use endurance exercise as a non- pharmacological intervention for treatment of diabetes type 2 patients.
Zahra Hajhashemy, Elham Moslemi, Parvane Saneei,
Volume 21, Issue 2 (7-2021)
Abstract
Background: Although the relation of serum vitamin D levels with abdominal obesity has been investigated by previous observational studies, the results are inconsistent. In the current study, a dose-response meta-analysis was conducted on epidemiologic studies that evaluated this association in adults.
Methods: We performed a systematic search of all published articles, up to May 2020, in five electronic databases. A total of 41 observational studies that reported odds ratios (ORs) or relative risks (RRs) with 95% confidence intervals (CIs) for abdominal obesity in relation to serum vitamin D levels in adults were found.
Results: Meta-analysis on 36 cross-sectional studies (combining 44 effect sizes) with 257699 participants, illustrated that the highest serum vitamin D level in comparison with the lowest serum vitamin D level was significantly related to 23% decreased odds of central obesity (OR=0.77; 95%CI:0.71-0.83). This inverse association was also significant in almost all subgroups based on different covariates. Based on dose-response analysis, each 25 nmol/l increase in serum vitamin D levels, was related to 8% reduced risk of central obesity (OR=0.92;95%CI:0.85,0.99). After limiting the analysis to 23 effect sizes from 17 studies with representative population (242135 participants), the same results were obtained (OR=0.79; 95%CI: 0.71-0.87). Based on dose-response analysis on studies with representative populations, each 25 nmol/l increase in blood vitamin D levels was linked to 10% decreased central adiposity risk(OR=0.90; 95%CI: 0.82, 0.99).
Conclusion: In this meta-analysis of epidemiologic studies, we demonstrated an inverse significant relation between serum vitamin D levels and risk of central obesity in adults, in a dose-response manner. The same findings were obtained in representative populations.
