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Showing 2 results for Metabolic Disorder

Reza Ghadimi, Sadat Hoseini Seiyedi, Hasan Ashrafian Amiri, Seiyed Davoud Nasrollahpour Shirvani,
Volume 15, Issue 5 (7-2016)
Abstract

Background: In recent years, waist and hip circumference measurements simultaneously used as anthropometric factors to determine the prevalence of overweight and obesity in adults, in addition to Body Mass Index. Some studies have confirmed the relationship between the above mentioned factors and the hematological parameters of cardiometabolic disorders. This study aimed to determine the association between anthropometric factors and hematological factors in 25-60 years old couples of Babol, Mazandaran.

Methods: This cross-sectional descriptive study was conducted in spring 2014, on research population of 25-60 year old couples who were selected by random cluster. Data collected through a researcher-made questionnaire containing about demographic variables, underlying factors, dependent variables; its validity and reliability were confirmed. The collected data were analyzed by SPSS18 software.

Results: Men’s BMI had significant direct relationship with systolic and diastolic blood pressure, fasting blood sugar, cholesterol and triglycerides (p<0.05). Women’s BMI had a significant direct relations with systole and diastole blood pressure, fasting blood sugar and triglycerides (p<0.05). There was a significant direct relationship between men’s and women’s Waist/Hip Ratio (WHR) with systole and diastole blood pressure, fasting blood sugar, cholesterol and triglycerides (p<0.05). There was a significant direct relationship between men’s and women’s anthropometric indices (apart from the BMI) associated with serum biomarkers of cardiometabolic disorders (p<0.05).

Conclusion: The results showed that increased BMI and WHR in couples, increases the amount of cardiometabolic serum biomarkers and may directly and indirectly cause the risk of chronic diseases.


Mousa Khalafi, Marzieh Faramarzi, Kayvan Sharifmoradi,
Volume 23, Issue 2 (5-2023)
Abstract

Background: CTRP3 is known to be an adipose tissue-derived anti-inflammatory hormone that leads to improved insulin resistance. However, the effects of exercise training on this adipokine are poorly understood. Therefore, the aim of the present meta-analysis was to investigate the effect of exercise training on circulating CTRP3 levels in adults with metabolic disorders.
Methods: A comprehensive search was conducted in PubMed and Web of Science databases through October 2022 using the keywords "exercise training" and "CTRP3". The inclusion criteria for the current research included human studies with metabolic disorders, exercise training intervention, and circulating CTRP3 values. Standardized mean difference (SMD) and 95% confidence interval were calculated using random method.
Results: A total of 9 studies including 12 intervention arms and 365 participants with metabolic disorders were included in the meta-analysis. The results of data analysis showed that exercise training led to a significant increase in CTRP3 [0.57, (CI: 1.10 to 0.03) P=0.03]. Also, the results of the I2 test showed that there is a high and significant heterogeneity (I2 =84.59, P=0.001) and the results of the Egger test showed a significant publication bias (P=0.001).
Conclusion: Exercise training with a moderate effect size leads to a significant increase in circulating CTRP3 levels in individual with metabolic and cardiovascular diseases, which may be a mediator of the beneficial effects of exercise training.

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