Showing 7 results for Metabolism
Shahin Yarahmadi, Bagher Larijani, Mohammad-Hassan Bastan Hagh, Mohammad Pajouhi, Farzaneh Zahedi, Reza Baradar-Jalili, Mohammad Reza Amini, Kazem Zendehdel,
Volume 1, Issue 1 (7-2001)
Abstract
Background: Studies of the metabolic effects of Ramadan fasting on patients with type 2 diabetes mellitus are inconclusive.
Methods: Fifty-seven volunteers with type 2 diabetes underwent anthropometric and biochemical evaluation before and on the 14th and 28th days of Ramadan. Biochemical markers were measured by standard laboratory methods. Anthropometric measurements followed WHO criteria. Statistical analysis was by ANOVA for repeated measurements and Friedman’s two-way ANOVA, using SPSSv6 software.
Results: Daily cholesterol intake increased in all subjects (p<0.03). Body mass index increased (p<0.03) in women, but body mass index (BMI) and waist-to-hip ratio both decreased (p<0.01) in men. Blood pressure, fasting blood glucose and serum fructosamine did not change during the study. Plasma insulin (p<0.05), C-peptide (p<0.01) and insulin resistance (p<0.01) decreased only in men. Total and LDL cholesterol increased significantly in all subjects during the study.
Conclusion: Ramadan fasting does not alter carbohydrate metabolism or tissue insulin sensitivity in type 2 diabetes patients, given appropriate dietary education and rescheduling of oral hypoglycaemic medication. Lipid profile is unfavourably altered due to changes in both diet and biochemical response to starvation. Anthropometric indices improve in men but not women, possibly because of reduced physical activity in the latter.
Maryam Djamnezhad , Kurosh Djafarian, Mostafa Qorbani, Asal Ataie-Jafari, Saeed Hosseini,
Volume 14, Issue 1 (1-2015)
Abstract
Background: There is increasing interest about the relationship between metabolism, obesity and function of thyroid hormones in recent decades. This study aimed to determine the validity of a “thyroid and metabolism questionnaire” and its relationship with metabolism status and function of thyroid hormones.
Methods: It was a descriptive cross-sectional study on 164 people aged 20-64 years who were selected randomly from nutrition clinic. “Thyroid and Metabolism questionnaire” including 25 questions were completed for everyone. Biochemical parameters including serum level of T3, T4 and TSH were measured. Resting energy expenditure [REE] was measured by indirect calorimeter.
Results: The mean measured REE and calculated with Harris-Benedict formula were 1826.7 ± 475.34 and 2277.6 ± 454.54 kcal in men and 1410.8 ± 205.5 and 1670.73 ± 136.10 kcal in women respectively. The final score of this questionnaire had no significant association with measured REE. REE showed indirect relationship with serum level of T3, T4, T3/T4 and inverse relationship with TSH. Metabolism status of every participant was obtained via measuring and calculating REE with set and formula. The metabolism status of participants showed no agreements with metabolism status that predicted from “Thyroid and Metabolism” questionnaire. There was no significant association between metabolism status that was measured by indirect calorimeter and calculated from “Thyroid and Metabolism” questionnaire. From 25 questions of this questionnaire, only questions number 1, 4, 16 and 23 showed significant association with measured REE [P< 0.05].
Conclusion: Results of this study showed that “Thyroid and Metabolism” questionnaire had internal consistency, but not validity.
Mohammadreza Hamedinia, Tayebeh Amiriparsa,
Volume 17, Issue 2 (3-2018)
Abstract
Abstract: The purpose of the present study was the investigation of the published articles in sport and Persian peer- reviewed journals in the field of exercise metabolism during 2011 to 2015 years.
Methods: In this regard, 9 out of 27 published journals on sport sciences were selected and were extracted by referring to the related websites, Jahad Daneshgahi and the country Information Database for Articles. 766 articles were investigated during the process.
Results: According to measured indicators, 223 articles were placed in the field of exercise metabolism. The Most articles have been published in the Journal of Metabolism and Exercise. 53.57% of the published articles in this journal were in the field of exercise metabolism. The average number of authors for each paper was 3.28. State Universities’ share in the production of the articles was 78% alone and 17% in partnership with Azad University. The Most independent variables used in the studies, were aerobic training (endurance) which 29.09% of all variables used in the study were included. From of 223 investigated papers 89 papers have been investigated the responses to exercise and 134 papers have been investigated the adaptation to exercise Training. The most of the study subjects were students and mice, with 16.5 and 16.14%, respectively. The number of the study subjects used in each article was 23.62 people on average. Almost 60% of the articles did not investigate on any performance or physical indicators. Among the measured metabolic markers, the oxidant and antioxidant markers was in the first place (16.69%).
Conclusion: Regarding the above-mentioned results, coordination, prioritization and policy making in the field of exercise metabolic researches seems necessary.
Negin Chehrazi, Minoo Bassami, Sajad Ahmadizad,
Volume 17, Issue 5 (7-2018)
Abstract
Background: Prevalence of obesity and overweight in women increases the possibility of metabolic syndrome and diabetes. Based on the variety of the effects of different type of exercise and the differences in the upper and lower body muscle volume involved in the exercise, the effects of high intensity interval exercise with arm and leg ergometer on metabolism and insulin resistance might be different. The aim of this study was to compare the effect of upper and lower body interval exercise on carbohydrate metabolism and insulin resistance in obese women.
Methods: Twelve obese and overweight women (body mass index, 31.1±5.5 kg/m2) performed two interval exercise trials of 30-min on arm and leg ergometer with one week intervening. Interval exercise included 5 sets of 6 min in which 2- min activity at 85% VO2max and 4 min active rest at 45% VO2max was performed. Two blood samples were taken before and immediately after exercise for measuring glucose and insulin. VO2 and VCO2m were collected during exercise and used to calculate the amount of carbohydrate oxidation.
Result: Although interval exercise reduced the insulin concentration, responses of insulin to upper and lower body exercises were not significantly different (P>0.05). Glucose level reduced following interval exercise, and this reduction was significantly (P<0.05) higher following lower body interval exercise than upper body exercise. Similarly the reductions in HOMA-IR were significantly (P<0.05) higher following lower body interval exercise than upper body exercise. Interval exercise resulted in increases in oxidation of carbohydrate, though; responses to upper and lower exercises were not significantly different.
Conclusion: It could be concluded that interval exercise in obese women leads to changes in carbohydrate metabolism and insulin resistance, and that the changes in insulin resistance are related to type of exercise (upper and lower body), though carbohydrate oxidation is not.
Mahnaz Sanjari, Noushin Fahimfar, Fatemeh Hajivalizadeh, Safora Gharibzadeh, Kazem Khalaji, Zohreh Hosseinzadeh, Firozeh Hajipour, Kobra Gorgani, Afshin Ostovar,
Volume 20, Issue 1 (1-2021)
Abstract
Background: Osteoporosis is one of the most important health problems in the country due to fracture. Osteoporosis Research Center with more than 20 years of experience in this field tries to present achievements and activities of the management and treatment of osteoporosis in the country while introducing this center. This review aims to overview the osteoporosis research center activities on osteoporosis.
Methods: In these conventional review national and international databases were investigated on osteoporosis without any restriction on time and language. Also, other activities that are not reflected in the papers were obtained from the professional website and official reports.
Results: According to the strategic plan of the osteoporosis research center, the achievements of this center provided in in three areas of research (population-based studies, clinical studies, basic science studies and health system studies), technology (diagnostic, therapeutic technologies, service delivery models) and education (training students at different levels of education). Supplementary, patient education, general education, and service provider training).
Conclusion: Osteoporosis Research Center is recognized as the only specialized research center in the field of osteoporosis in the country. The center is trying to improve its position as a regional center in the field of osteoporosis by relying on its strategic and operational plan, in addition to maintaining its current position.
Fatemeh Bandarian, Nazli Namazi, Mohammad Pajouhi, Mohammadreza Amini, Neda Mehrdad, Bagher Larijani,
Volume 20, Issue 1 (1-2021)
Abstract
Endocrinology and Metabolism Research Institute (EMRI) was established in 1993. EMRI has progressed step by step from the beginning and has reached maturity in the last 25 years. EMRI has expanded, advanced in human resources and infrastructures (laboratories and new technologies) and gained first rank in endocrine research in various fields. It has also worked with regional and international organizations such as the World Health Organization (WHO), the International Osteoporosis Foundation (IOF), and the American Clinical Endocrine Society (AACE). This article provides an overview of EMRI activities over a quarter of a century.
Mr Mohsen Taimouri, Mr 2- khosro Jalali Dehkordi, Mehdi Kargarfard, Ms Farzaneh Taghian,
Volume 24, Issue 6 (2-2024)
Abstract
Materials and methods: In arandomized controlled clinical trial study, 56 older patientswith type 2 diabetic osteoporosis (age: 68.18±3.67 yr; weight: 78.13±7.65 kg, body mass index: 28.40±1.76 kg/m2) were randomly assigned to either the exercise+Full-body pulsed electromagnetic field (PEMF+Ex, n=18) exercise + placebo full-body PEMF (PPEMF+Ex, n=17) and a full-body PEMF alone (PEMF, n=21). PEMF was applied for the whole body using a full-body mat three times per week, 60 minutes for 12 weeks, with a multicomponentexercise protocol that includes flexibility, aerobic exercise, strengthening, weight-bearing, and balance exercises followed by whole-body vibration (WBV) training. The body composition, bone mineral density (BMD), bone metabolism markers (phosphorus, calcium, sclerostin, osteocalcin, Bone-specific alkaline phosphatase (BALP)) before and after the intervention. The data were analyzed using the dependent t test and the two-way repeated measures ANOVA at the level of less than 0.05. Results: After 12 weeks of intervention, there is a significant difference in the serum levels of bone mineral density and bone metabolism markers (phosphorus, calcium, sclerostin, BALP) between the groups (p < 0.05). However, the bonferoni post-test showed a increase in serum levels of BMD, phosphorus, sclerostin, BALP with a significant decrease in calcium in the PEMF+MCEx group in compared to alone PEMF group. Discussion: The findings showed that the PEMF rehabilitation method combined with multicomponent exercise is more effective and safe than exercise or PEMF only for improving BMD and bone metabolism markers in the type 2 diabetic population with osteoporosis.
