Reza Omidi Ghanbari, Rahman Soori, Ahmad Hemmatfar,
Volume 18, Issue 5 (7-2019)
Abstract
Background: Adropin is a peptide hormone playing a role in energy homeostasis and prevention of obesity. The aim of this study was to investigate the effects of aerobic exercise with low intensity on serum adropin levels and insulin resistance index (HOMA-IR) in obese sedentary adolescent boys.
Methods: This study was carried out in a quasi-experimental design. 26 obese adolescent boys were recruited (Mean ± SD: 13.4±0.81 yr; weight: 85.44±8.51kg) and were randomly assigned into two groups: aerobic exercise and control group. The training group performed running with intensity of 50-65% of maximal heart rate, three times a week for 10 weeks. Before and after intervention, blood sampling for measurement of serum adropin, fasting insulin and glucose was carried out. Data were analyzed by paired t-test and independent t-test at significant levels of P≤0.05.
Results: Weight (P=0.001) and body fat percent (P=0.017) showed significant reduction in aerobic group in posttest compared to pretest and control group. Serum adropin levels were increased significantly in aerobic exercise group compared to pretest and control group (P=0.0001). Significant correlation was seen between changes of adropin with changes of weight, body fat percent and HOMA-IR (P≤0.05).
Conclusion: According to the relationship between adropin with body composition and insulin resistance and also, its influence from aerobic exercise, adropin may play a special role in weight and obesity management.
Mahmood Darvishi, Vahid Valipour Dehnou, Rasoul Eslami,
Volume 26, Issue 1 (4-2026)
Abstract
Background: Childhood obesity is linked to adult obesity and chronic diseases. Therefore, this study investigates the effects of High-intensity functional training (HIFT) and High-intensity interval training (HIIT) on physiological variables and functional capacity in overweight and obese, untrained adolescents.
Methods: Thirty overweight and obese adolescents were randomly assigned to three equal groups: control [14.30 ± 0.82 years, body mass index (BMI)= 30.23 ± 2.11], HIIT (14.10 ± 0.87 years, BMI= 29.17 ± 2.51), and HIFT (13.40 ± 0.82 years, BMI= 29.42 ± 2.56). Participants in the experimental groups followed an HIIT and HIFT training protocol for six weeks. Before and after the intervention, anthropometric indices and serum levels of leptin and omentin were measured. Data were analyzed using mixed ANOVA and Tukey’s post hoc tests.
Results: HIFT significantly reduced body weight and BMI compared to the control group (P< 0.05), while HIIT showed no significant effect (P> 0.05). Serum leptin levels were significantly lower in both experimental groups compared to the control group (P< 0.01). Notably, only HIFT significantly increased omentin levels compared to the control group (P< 0.001). No significant effect was observed on the waist-to-hip ratio (P> 0.05).
Conclusion: The present study demonstrates that both HIFT and HIIT can lead to improvements in anthropometric indices and serum levels of omentin and leptin in overweight and obese adolescents. However, HIFT appears to be a more effective intervention.
