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Showing 22 results for Prevalence

Bagher Larejani, Farzaneh Zahedi,
Volume 1, Issue 1 (7-2001)
Abstract

Diabetes mellitus is a common disease and its incidence and prevalence are increasing in most populations. The trend is particularly worrying in developing countries. The number of diabetic patients in Iran is estimated at 1.5 million. The distribution of diabetes in Iran has been the subject of several surveys. Disease prevalence rates, for all forms of diabetes, of 7–17% have been variously reported in several adult urban populations. Geographical prevalence is not uniform, however, and the prevalence of type 2 diabetes mellitus has been reported at 3-5% in rural communities. A screening program conducted at different locations of Iran revealed that nearly 50% of people with type 2 diabetes were unaware of their condition. Not surprisingly, therefore, that the incidence of complications for diabetes is high in Iran. A battle is being waged on all fronts at present to control the socio-economic scourge that is diabetes mellitus. A national program has been designed for the primary, secondary, and tertiary prevention of diabetes. The major strategies that it puts forwards are screening, the identification of high-risk groups, public education, and the training of specialist care providers. This article reviews the epidemiological features of diabetes in Iran.
Bagher Larijani, Ebrahim Osfouri,
Volume 1, Issue 2 (7-2002)
Abstract

Introduction: The prevalence of type 2 diabetes is increasing daily all around the world and is a serious threat to the well-being of the community in terms of renal failure, cardiovascular disease, blindness, and neuropathy. The assessment of difference screening approaches is of great importance in this disease. We compared ADA and WHO criteria for the diagnosis of type 2 diabetes.
Methods: 982 individuals (age range: 30 to 64 years), residents of the city of Bushehr, were chosen by systematic random sampling for this study, each providing a fasting blood sample for a standard oral glucose tolerance test. Plasma glucose was measured by the glucose oxidase-peroxidase method, using a Technikon RA1000 autoanalyser. Data was analysed with the Chi-squared and Student’s t tests and, when required, Fisher’s Exact test.
Results: 354 (36%) men and 628 (64%) women took part in this study. 42.9% were in the 30-39 age group. 69 (20 men and 49 women) of the 982, that is 7% of the sample, had known diabetes before recruitment into the study. The crude prevalence of type 2 diabetes and impaired glucose tolerance using WHO criteria was 13.6 and 15.6 percent, respectively. The crude prevalence of type 2 diabetes using ADA criteria was 13.4 percent. 51% of patients were already aware of their disease. The sensitivity of fasting blood glucose testing for detecting diabetes was 45.8% using WHO and 62.5% using ADA criteria. Both sets of criteria were equally specific.
Conclusion: Given the overall prevalence of glucose intolerance (impaired glucose tolerance and type 2 diabetes) in Bushehr, it should be considered as a high-prevalence area for diabetes. Accordingly, we recommend screening with fasting plasma glucose and oral glucose tolerance testing.
H Fakhrazadeh, R Pour-Ebrahim, M Nouri , R Heshmat, E Javadi, I Rahimi, B Larijani,
Volume 3, Issue 0 (7-2004)
Abstract

Introduction: Urbanization, establishment of sedentary life style and unhealthy diet in association with environmental stress has led the cardiovascular risk factors to prevail in the metropolitan city of Tehran. Survey of lifestyle related cardiovascular risk factors is one of the priorities of Tehran university population laboratory in the 17th zone of Tehran.
Methods:1573 inhabitants of 17th zone of Tehran were recruited by one stage cluster random sampling according to the model of WHO MONICA project.
Results: 58.6% of men and 64% of women had BMI ≥ 25 kg/m2. 41.7% of men and 37.6% of women had hypertension. 8.9% of men and 12.2% of women had diabetes. 34.4% of men and 44.6% of women had total cholesterol ≥ 200 mg/dl. 34.1% of men and 32.6% of women had triglyceride ≥ 200 mg/dl. 34.7% of men and 4.2% of women were regular smokers. 21% of participants had positive family history of cardiovascular disorders.
Conclusion: The prevalence of hypertension in this region is high, that of dyslipidemia relatively lower than the other studies performed in Iran. The prevalence of Diabetes and overweight /obesity is high and comparable to other Iranian studies. It seems that the population of this zone is at high risk for stroke and then coronary heart disease. This fact must be considered in the future interventional programs to control cardiovascular risk factors in the region.
Shahin Yarahmadi, Bagher Larijani, Ebrahim Javadi, Mohammad-Hassan Bastan Hagh, Mohammad Pajouhi, Reza Malekzadeh, Mahmood Mahmoudi, Aliereza Shafaei, Mohammad-Reza Mohajeri-Tehrani, Ali Rajabe, Mohammad Farshadi,
Volume 3, Issue 1 (5-2004)
Abstract

Celiac disease and typel diabetes mellirus have been linked to the same HLA markers and chromosomal loci, which may account for the concurrence of the two disorders in a significant number of patients. This study was designed to investigate the frequency of anti-gliadin antibodies, a marker for celiac disease, in diabetic patients.
Methods: In this study, 182 diabetic patients (52 with typel and 130 with type2 diabetes) were screened for anti-gliadin IgG by indirect immunofluorescence. Age range was 3-29.5 and 42-65 years for type 1 and type 2 diabetes groups.
Results: Anti-gliadin IgG was found in 1.9% and 1.5% of patients with type land type 2 diabetes. In Tehran, 0.02% of healthy blood donors have been reported to be seropositivitive for anti-gliadin IgG.
Conclusion: The prevalence of anti-gliadin seropositivity in type 1 and type 2 diabetics, was respectively 30 and 24 times higher than the general population of Tehran. This concurs with other reports indicating higher occurrence of celiac disease in diabetic populations. The rather low sensitivity and specificity (both around 80%) of the antigliadin antibody test has made it a suboptimal diagnostic test. However, it is quick and inexpensive and can be suitable for screening programs. We recommend the test in all at-risk populations including diabetics.
Behzad Shamsi, Mahin Hashemipour, Sayed Hossein Saadat, Sayed Mohammad Hasan Emami, Zahra Abdyazdan, Akbar Hasanzadeh, Khosrow Khaibi, Sasan Haghighi, Silva Hovsepian,
Volume 3, Issue 1 (5-2004)
Abstract

Increased prevalence of Helicobacter Pylori (HP) infection is a common feature in diabetics, which is attributable to the presence of diverse predisposing factors. In this study, the prevalence of HP infection has been investigated in type 1 diabetic children.
Methods: In a cross-sectional study, anti-HP antibody (IgG) was measured in 75 type 1 diabetics (aged 2-18 years) and the results were compared with 75 healthy children who were matched for age, sex and socio-economic status. In seropositive diabetic patients with gastrointestinal (GI) symptoms, gastroduodenoscopy was performed to establish the diagnosis.
Results: Sera were positive for anti-HP in 22.7% of diabetics versus 17.3% in controls (P>0.05). No significant difference was observable between seropositive and seronegative diabetic groups as regard to age, sex, age at onset of diabetes, number of outpatient visits during the last 6 months, HbAlc and insulin requirements. Gastrointestinal symptoms were more common in diabetics than the healthy controls the prevalence of these symptoms, however, did not differ significantly between seropositive and seronegative diabetics.
Conclusion: The study indicated that type 1 diabetes is not associated with increased risk of HP infection. Further studies are required to investigate the impact of HP infection treatment on the glycemic control in diabetic children.
Ehia Garshaspi, Seied Mohsen Khoshniat Nikoo, Mariam Abbasian, Bita Radjabipour, Nader Fallah,
Volume 4, Issue 1 (7-2004)
Abstract

Background: Currently different criteria are used to diagnose Gestational Diabetes. ACOG (American college of obstetric and Gynecology) accepted NDDG's (criteria National Diabetes Data Group) Criteria and ADA (American Diabetes Association) accepted Carpenter Caustan’s. Although both of these criteria have been achieved by O Salivan and Mahan’s reaserches, the number of patients has been diagnosed are different .The aim of this study was to compare Gestational Diabetes prevalence according to Carpenter Caustan’s and NDDG’s Criteria.
Methods: 1200 pregnant women were screened in a prenatal care clinic. Patients with definite diabetes were excluded. According to universal GDM screening method, for all of the patients GCT and GTT (if GCT > 130) were preformed. The results evaluated according to Carpenter Caustan’s and NDDG’s criteria. Results: In this screening, 377 participants had positive GCT, according to Carpenter and Caustan’s criteria 83 women (6.9%), and according to NDDG criteria 50 women (3.6%) had Gestational Diabetes Mellitus. If the cut of point of GCT was 140 mg/dl instead of 130 mg/dl, according to Carpenter and Caustan’s criteria 16 women (18.1%), and according to NDDG 4 patients (9%) were missed.
Conclusion: Regarding the significant difference between two methods in diagnosis of gestational diabetes mellitus, assessment of each method value in improving prognosis and outcomes is necessary. According to the results the cut of point of 130mg/dl, as recommended in previous studies, has more accuracy for screening.
Azam Teimoury, Zhila Behrouz, Masoud Amini,
Volume 4, Issue 1 (7-2004)
Abstract

Background: Hypertension and dyslipidemia are common in patients with type 2 diabetes mellitus. The high prevalence of cardiovascular disease in diabetic patients is, in part, related to these two risk factors. This study was performed to determine the prevalence of hypertension and dyslipidemia in newly diagnosed patients with type 2 diabetes mellitus in Isfahan.
Methods : In this cross – sectional study during 2001 – 2003, 310 newly diagnosed type 2 diabetic patients, in Isfahan endocrine and metabolism research center, were studied. Height, weight, blood pressure, Plasma lipid and lipoproteins, and HbA1c were determined for all subjects.
Results: Mean age at presentation was 489.83 years, and mean BMI was 28.44.62 Kg/m2. Hypertension was present in 32.9%, hypercholesterolaemia in 61.3%, hypertriglyceridaemia in 61.6%, high LDL in 77.3%, and low HDL in 67.8% of these patietns. The mean systolic and diastolic blood pressure were 119.0816.59 and 70.0214.02mmHg, respectively. The mean for total cholestrol was 216.1043.65, for triglyceride 207.46105.67, for LDL 124.7331.45, and for HDL 43.119.29 mg/dl.
Conclusion: Hypertension and dyslipidemia are common in newly diagnosed type 2 diabetic patients. This fact demonstrates the importance of early interventions for proper diagnosis and treatment of these two risk factors in diabetic patients.
Bagher Larijani, Farid Abolhasani, Mohammad Reza Mohajeri-Tehrani, Ozra Tabtabaie,
Volume 4, Issue 3 (5-2005)
Abstract

Background: Diabetes mellitus is one of the chronic metabolic diseases with several organ damages that dearese life span. Prevalence of known diabetes appears to be increasing in most countries, presumably due to increasing the prevalence of risk factors such as obesity, lower physical activity and improved diagnosis. WHO expect the number of adults (20 years and older) with diabetes rises up to 300 millions in 2025. In view of the worldwide geographic differences in diabetes and lack of documented informations about prevalence of diabetes in Iran, we assigned this study.
Methods: The base of our study for assessment of prevalence of diabetes in Iran was results of ״Health and Disease Study in Iran, 1999״. We used epidemiologic model (DisMod) for estimating the incidence of diabetes in Iran. Results: The prevalence of diabetes in over 20 years of Iranian population in 2000, was 1.6 million or 4.67%. Also it is estimated up to 100000 persons have been affected by type II diabetes.
Conclusion: The true limitation of our study was limitations of documents about estimated of proportion of true prevalence to prevalence of known diabetes.
Hassan Safaei, Masoud Amini, Jila Behroz, Azam Teimori,
Volume 5, Issue 3 (5-2006)
Abstract

Background: Retinopathy is one of the microvascular complications of diabetes which is strongly related to the glycemic control and duration of the disease. According to results of other studies, the prevalence of retinopathy has been reported 5-30% in newly diagnosed patients whit type 2 diabetes (T2DM). The aim of this study was to determine the prevalence of idabeteic retinopathy among newly diagnosed T2DM patients in Isfahan, Iran.
Methods: From july 2001 to March 2004, 710 newly diagnosed patients with T2DM were recruited in this study. Patients with duration of diabetes less than 1 year were considered as newly diagnosed ones. Along with physical examination and laboratory measurment for FBS, HbA1c, lipid profile, urea, Creatinin, and 24 houre urin examniation for albumin, retinoscopy was performed by an experienced ophttalmologist.
Results: In this study, 286 men and 424 women were investigated. The mean age of patients at presentation and the mean duration time of diabetes were 48.8 ±9.8 years (range 31-72years) and 8.6±5.4 months respectively. The prevalence of retinopathy was 9 % (9/8% in males and 8.5% in females). Logistic regression analysis revealed that BMI, diastolic blood pressure and 24 hour urine albumin, were independent risk factors for developing retinopathy.
Conclusion: Nevertheless of relatively moderate prevalence of diabetic retinopathy in our study as compared with other studies, it is necessary to perform retinal examination in newly diagnosed T2DM patients in order to prevent the sight-threatening outcomes of diabetic retinopathy.
Negar Horri, Mahboubeh Farmani, Sasan Haghighi, Goshtasb Sattari, Zahra Pournaghshband, Masoud Amini,
Volume 5, Issue 3 (5-2006)
Abstract

Background : Women with polycystic overy syndrome (PCOS) are sussceptible for developing type 2 diabetes (T2DM) and cardiovascular diseases. In view increased prevalence of T2DM in patients with PCOS and priority of prescription agents capable to decrease insulin resistances for them, It is important to diagnose PCOS in T2DM patients. The aim of this study was to evaluate the prevalence of PCOS in T2DM women.
Methods : Using ‘1990 National Institute of Child Health and Human Development Conference of PCOS’ criteria, 157 premenopausal women with T2DM were assigned into PCOS and non – PCOS groups after they were examined for the evidences of clinical PCOS. A questionnaire on reproductive history was completed and the waist circumference, weight, height and BP were measured for each participant. Biochemical tests were performed in both groups, but hormonal measurements were requested only for PCOS group.
Results : The prevalence of PCOS was high (about 8%) among subjects. Patients with PCOS had significantly lower age at the onset of diabetes, higher BMI and waist circumference. The differences in BP, serum TG, HDL, LDL, cholesterol and HbA1c were non – significant between 2 groups and insulin resistance is more.
Conclusion : PCOS is prevalent in diabetic women and Insulin resistance is more likely in those with both PCOS and T2DM resistant than whom with diabetes alone. Emphasis on reducing insulin resistance may be of benefit to achieve a better diabetes control in these patients.
Mohammad Jafar Mahmoudi, Hooryye Saghafi, Hossein Fakhrzadeh, Ramin Heshmat, Alireza Shafaei, Bagher Larijani, ,
Volume 5, Issue 3 (5-2006)
Abstract

Background: Dyslipidemia accounts as a major risk factor for cardiovascular diseases. The aim of this survey was to determine the prevalence of dyslipidemia among relatives of patients with premature coronary artery disease (PCAD).
Methods: As a cross-sectional study 232 first degree relatives of patients with PCAD were recruited. A questionnaire was filled out by all of the participants all of them undergone physical examination and blood sampling. Lipid profile was categorized according to the NCEP: ATPIII criteria.
Results: Total Cholesterol>200 in 29.7%, LDL>160 in 10.3%, HDL<40 in 12.9%, TG>200 in 32.8%, ApoB100>130 in 14.2%, Apo A1<90 in 1.7% and LP(a)>30 in 47% of participants were seen. Serum levels of TG were significantly higher in men than women levels of HDL and ApoA1 were lower in men than women. The Prevalence of dyslipidemia among relatives was 59.6%.
Conclusion: In view of high prevalence of Dyslipidemia among relatives of PACD patients, active interventions in order to primary prevention of cardiovascular diseases via exact screening is recommended.
Fereshteh Kalantari, Silva Hovsepian, Sasan Haghighi, Masoud Amini,
Volume 6, Issue 3 (5-2007)
Abstract

Background: The aim of this study was to determine the prevalence of cardiovascular disease (CVD) risk factors among type 1 diabetic patients referring to Isfahan Endocrine & Metabolism Research Center.

Methods: In this cross-sectional study, the prevalence of CVD risk factors including dyslipidemia, smoking and hypertension was determined in type 1 diabetic patients aged 15-30 years.  Serum cholesterol <170 mg/dl, LDL<100 mg/dl , HDL>35 mg/dl , TG<150 mg/dl, systolic blood pressure<120 mmHg and diastolic blood pressure<80 mmHg were considered as optimal control levels.

Results: Among 219 studied diabetic patients (mean age=22.5±10.3, female/male=120/99), the mean cholesterol and HDL-C level was higher in women (176±34.9, 46.4±34.1) than men (162.9±32.4 vs. 41.5±10.1) (P<0.05). The prevalence of smoking, hypercholesterolemia, LDL>100 mg/dl, HDL<35 mg/dl, hypertriglyceridemia and hypertension was 6.9% (n=15), 47.4% (n=104), 53.5% (n=117), 22.8% (n=50), 18.3% (n=40) and 7.7% (n=17), respectively. HDL<35 mg/dl was more prevalent among men as compared with women but cholesterol> 170 was more frequently detected in women (P<0.05).

Conclusion: Considering the rather high prevalence of CVD risk factors in type 1 diabetic patients in Isfahan, and in view of modifiability of these risk factors, educating patients on appropriate glycemic control and increasing physical activity is necessary as well as close monitoring of these risk factors.


Farzad Hadaegh, Azadeh Zabetian, Fereidoun Azizi,
Volume 6, Issue 4 (6-2007)
Abstract

In April 2005, the International Diabetes Federation (IDF) has formulated a new worldwide definition of the metabolic syndrome in a global consensus statement built on earlier WHO, the ATPIII definitions. The aim of this study was to estimate the prevalence of this syndrome using the IDF definition among Iranian adults and to compare it with the prevalence estimated using the two other definitions. 

Methods: The prevalence of the MES was determined according to the three different definitions in 10368 men and women aged≥20 years participated in the cross-sectional phase of the Tehran Lipid and Glucose Study (TLGS). To assess the degree of agreement between different MES definitions, the k test was used. 

Results: The prevalence of MES (95% confidence interval) was 32.1% (31.2-33.0) by the IDF definition, 33.2% (32.3-34.1) by the ATPIII and 18.4% (17.6-19.2) according to the WHO definition. The sensitivity, specificity and concordance of the IDF definition for detecting MES were 91%, 89% for the ATPIII definitions and 73%, 77% for the WHO definition, respectively. The k statistics for the agreement of the IDF definition was 66.3±0.01 with the ATPIII and 39.5±0 with the WHO definition.

Conclusion: In the Iranian population, the IDF definition for MES has a good concordance with the ATP III definition and a low concordance with the WHO definition.


Adel Jahed, Farhad Hosseinpanah, Fereidoun Azizi,
Volume 7, Issue 1 (7-2007)
Abstract

Background: LADA is a subgroup of type 1 diabetes mellitus characterized by its age at diagnosis being more than 30 years, presence of Glutamic Acid Decarboxylase65 (GAD65) autoantibody, and insulin independency in the first 6 months of diagnosis. Our aim was to determine the prevalence and predictors of LADA in a large population-based drug naïve newly diagnosed adult diabetics of Tehran urban population.

Methods: In this cross-sectional study, all newly diagnosed diabetics of Tehran Lipid and Glucose Study aged more than 30 years who were not initialy treated with insulin were tested for GAD antibody titer. Thirty two GAD antibody positive (LADA) and 556 GAD antidody negative patients (type 2 diabetics) were found and compared for anthropometric, clinical and laboratory features.

Results: Mean age of all 588 cases was 54.2±11.6. The prevalence of LADA was %5.44 (CI %95: %3.6-%7.3). Age, sex, BMI, family history of diabetes, diastolic blood pressure, glucose and lipid profile and the prevalence of metabolic syndrome were similar between LADA and type 2 diabetics. Systolic blood pressure were greater in type 2 diabetics than in LADA group. No model could predict the result of GAD antibody measurement.

Conclusion: autoimmune process is present in early stages of diabetes in %5.4 of newly diagnosed adult diabetics assumed to suffer type 2 diabetes mellitus. Using clinical and laboratory features, no model could reliably screen these cases. It seems reasonable to test GAD antibody in all such cases to early find persons more probable to have a more rapid process toward pancreas insufficiency.


Sommayeh Rashid Shomali, Vahideh Montazeri, Seyed Mohammad Akrami, Ramin Heshmat, Bagher Larijani,
Volume 7, Issue 1 (7-2007)
Abstract

Background: High prevalence of consanguineous marriages has been reported in Iran. Since this pattern of marriage may increase the prevalence of diseases with autosomal recessive pattern of expression, the study was assigned to determine this among patients referred to diabetes and osteoporosis clinics of Dr Shariati hospital, Tehran, Iran.   

Methods: The consanguineous marriage was studied among 1789 couples of three successive generations via Questionnaire.

Results: The prevalence of consanguineous marriages in three successive generations was 9%, 17% and 19%, respectively with an increasing pattern of prevalence. Overall the prevalence of first cousins marriage was 10% with 69% among consanguineous marriage group. The higher the level of education, the lower the prevalence of consanguineous marriage.

Conclusion: In view of the increasing prevalence of consanguineous marriage that may be followed by some trouble consequences about disease expression, it seems necessary to provide facilities for genetic counseling before marriage for youth.


Azadeh Zabetian, Farzad Hadaegh, Maryam Tohidi, Farhad Sheikholeslami, Feridoun Azizi,
Volume 7, Issue 1 (7-2007)
Abstract

Background: The aim of this study was to examine the prevalence of the metabolic syndrome (MetS) and its association with coronary heart disease (CHD) in Iranian older individuals.

Methods: In this cross-sectional study, the prevalence of the MetS was determined according to the Third Adult Treatment Panel (ATPIII), the World Health Organization (WHO) and the International Diabetes Federation (IDF) definitions in 720 men and women aged≥65 years. Logistic regression analysis was used to estimate the Odds Ratio (OR) of developing CHD in model 1 an age adjusted model, in model 2 adjusted for age, smoking status, premature history of CHD and LDL cholesterol and in model 3 adjusted for mentioned variables in model 2 plus the components of the MetS according to each definition.

Results: The prevalence of MetS was 50.8%, 41.9% and 41.8% by ATPIII, IDF and the WHO definitions, respectively. IDF had high agreement with the ATPIII definition. In model 2, the ATPIII and the WHO definitions of MetS were associated with CHD by the odds ratio of 1.6 (1.1-2.2) and 1.7 (1.9-2.4), respectively. In model 3, obesity (WHO definition) and high blood pressure (ATPIII and WHO definitions) were associated with CHD.

Conclusion: As defined by the ATPIII and WHO definitions, the MetS was associated with CHD even after adjustment for the conventional CHD risks, but after further adjustment for their components none of these definitions showed association with CHD.


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Volume 13, Issue 6 (9-2014)
Abstract

Background: Oral health is an important issue in elders’ life in both food consumption style and their self-esteem. The aim of this study was to survey the oral health among aged people in Gorgan city. Methods: In a cross sectional study and through a standard questionnaire, the data of 869 aged people who were resident in the areas where were covered by 4th and 5th Health Station of Gorgan Health Center, has been analyzed. Participants (over 60 years old persons) entered in the study through a census method are asked about their oral health by trained persons. Data analyzed by descriptive statistics and Chi-Square test. Alpha level set at 0.05. Results: Complete toothless was 54.3 percent in male and 62.6 percent in female. Totally teeth preservation rate was 6.4 percent in male and 1.5 percent in female. The mean and standard deviation of tooth loss were 22.5±12.4 in male and 24.4±11.2 in female. The Complete toothless significantly was high in single people compared with married one. Completely toothless was low among aged people with less than or equal to four children and was low among aged people in the worst status of economic situation. Conclusion: Oral health among the study population was in a bad situation. For preservation of teeth till adult age, appropriate planning and interventions is necessary.
Habibeh Taghavi Kojidi, Farshad Farzadfar, Niloofar Peykari, Bagher Larijani, Shadi Rahimzadeh, Ehsan Rezaei-Darzi, Sahar Saeedi Moghaddam,
Volume 15, Issue 2 (1-2016)
Abstract

Background: Thyroid cancer is the most common form of endocrine cancer. The age and gender-adjusted incidence of thyroid cancer has increased faster than that of any other malignancy in recent years, with the increased incidence seen in both genders, all ethnic backgrounds and all sizes of thyroid cancer. It appears that the rise in thyroid cancer incidence is not only due to medical surveillance and improved disease detection. In Iran, also scattered studies had been accomplished in different provinces and requirement to more attention and planning for thyroid cancer. Thyroid cancer’s control and prevention requires to the evidence–based strategies in different population groups based on national and provincial comprehensive studies on the prevalence and incidence. Thus we aimed to provide the comprehensive information about thyroid cancer prevalence and trend in national, provincial levels among Iranian population.

Methods: In this study we used some steps respectively to show how thyroid cancer prevalence changes in 1990 to 2010 between different provinces. We aggregate cancer registry data set by province, age categorized, gender and merge with other national covariates that were gathered in Iran. Then, linear regression model and logistic regression model were used to modeling and predicting for other provinces and years.

Results: Mean of thyroid cancer prevalence displayed that prevalence increased with increase in years especially more rapidly from 2002-2010 the prevalence rates were estimated to be (0.0-0.25) and (4.2-13.7) per 100000 in 1990 and 2010 respectively and increased in both females and males. Female to male ratio was 2.5. Highest prevalence thyroid cancer were in four provinces of Iran, Isfahan (mean rate 4.3 per 100000), Yazd (mean rate 4.1 per 100000), Tehran (mean rate 4 per 100000) and Qazvin (mean rate 3.1 per 100000) respectively.

Conclusion: Iran map displayed with increase in years, thyroid cancer prevalence become larger. Additional research on the risk factors for thyroid cancer is needed to explain the difference of thyroid cancer prevalence between provinces.


Kourosh Sayehmiri, Abbass Sheykhi, Forghan Rabiei Fakhr , Alireza Yadegarazadi, Milad Azami,
Volume 15, Issue 4 (5-2016)
Abstract

Background: Patients with type 2 diabetes mellitus are more prone to depression. Prevalence of depression in the Iranian results of studies is different. Therefore, the present study aims to study the prevalence of depression in Iranian patients with type II diabetes mellitus.

Methods: This study is a systematic review based on PRISMA guideline for systematic reviews and meta-analyses study. Literature searches of, Scopus, MEDLINE, PubMed, Science Direct, Cochrane, EMBASE, Web of Science, Springer, Online Library Wiley, Google Scholar search engine and Iranians database for publications in Persian and English were conducted up to December 2015. Searches were performed by two researchers independently using standard keywords. Reviewers extracted data and assessed methodological quality in duplicate.  Meta-analysis was performed using STATA, version 11.1 to combine data through Random Effects Model.

Results: Sixteen studies and 3,284 subjects with a mean age of 48.6 years were included in the analysis.  The prevalence of depression in Iranian patients with type II diabetes was estimated 54.8% (95% CI: 43.5- 66.1). This range for males and females were calculated 32.2 %( 95% CI: 16.3-48.1) and 60% (95% CI: 46.4-73.7), respectively. The highest prevalence of depression was in the center of Iran (60%) and the lowest rate was in the west of Iran (38%).

Conclusion: Regarding to high prevalence of depression in patients with type II diabetes, Implementation of screening program for psychiatric disorders, especially depression as well as conducted psychiatric consultation routinely for diagnosis and treatment of depression in these patients it seems necessary.


Maryam Zangeneh, Nahid Mohamadi, Tahereh Kolahi, Ghodratolah Roshanei, Masood Khodaveisi, Arezoo Shayan,
Volume 17, Issue 3 (3-2018)
Abstract

Background: Gestational diabetes is one of the most common metabolic disorders during pregnancy. The purpose of this study was to determine Prevalence of Gestational Diabetes Mellitus in Pregnant Women Referred to Therapeutic and Health Centers in Hamadan Town.
Methods: This descriptive-sectional study was done in the year2014 on 620 pregnant women Referred to The health Centers in Hamadan Town. The necessary information was collected by means of a self-made
Questionnaire. The scientific validity of the questionnaire Comments 15 members of the faculty of nursing and midwifery. The necessary amendments were made. To determine the reliability question a pilot study on 10 patients was performed twice with an interval of 10 days and offer 0/91 reliability was confirmed Then the data was analyzed by using SPSS software, independent Fisher test, Chi-square and a=0.05 was taken as the significant level.
Results: 110 of the 620 cases studied (almost 17.1%) suffered from gestational diabetes mellitus and 38 cases of all (almost 6.1%) had overt diabetes. Mean age of the pregnant women was30.6±5 and BMI25.3±4.1 their mean number of pergment was 1.6±0.8. Increasing the hours of mother's work at home, body mass index, household size, number and history of abortion, number of pregnancies and delivery, and the history of diabetes in the family, the chance of having diabetes also significantly increases (P<0.05).
Conclusion: Regarding the great importance of gestational diabetes and its complications on the fetus, diabetes preventive practices demand special attention to pregnant women Regarding the trend of increasing the incidence of pregnant women to gestational diabetes mellitus and the effect of demographic and obstetric factors on its development, screening for women before admission for diabetes and healthy lifestyle education is recommended.

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