Showing 3 results for Myocardial Infarction
Hossein Fakhrzadeh, Iraj Nabepoor, Mohammad Rayani, Ali-Reza Vassigh,
Volume 2, Issue 1 (5-2003)
Abstract
Background: We estimated the prevalence of angina pectoris (AP) and myocardial infarction (MI) in the hyperlipidaemic population of Bushehr using the ROSE questionnaire and ECG changes using the Minnesota code.
Methods: 1036 residents of Bushehr (in southern Iran), aged 30-64 years, were enrolled as part of a 2-year cross-sectional prevalence study of diabetes mellitus and other risk factors for coronary heart disease. All participants completed a ROSE questionnaire and underwent 12-lead electrocardiography. ECG strips were interpreted according to the Minnesota code. The criteria for diagnosing AP was grade 1 or 2 on the angina pectoris diagnostic scale, and for MI, code 1.1 of the Minnesota code or a history of myocardial infarction. Results: The crude prevalence of hypercholesterolaemia was 47.6%, and its age-adjusted prevalence 50.3% in women and 43.9% in men. Mean serum cholesterol was 204.2±49.5mg/dl in women and 195.0±46.1 in men (p=0.003). The prevalence of AP was 4.9%, which, after adjustment for age, came to 5.6% in men and 4.6% in women. The prevalence of AP was 6.3% in subjects with high cholesterol and 3.6% in subjects with normal cholesterol levels (p<0.05). There was a strong association between AP and hypercholesterolaemia in men (p<0.0005). The crude prevalence of MI was 4.1% in subjects with hypercholesterolaemia and 0.9% in subjects with normal cholesterol (p<0.05). In multivariate analysis, MI was correlated with hypercholesterolaemia in both sexes (p<0.05). Similarly, MI in both men and women was associated with diabetes, and in men alone with hypertension (p<0.05). Conclusion: It is imperative to reduce the average cholesterol level of the population of Bushehr in order to decrease the incidence of AP and, ultimately, MI. Interventions to improve people s lifestyle are of one of the effective measures that may be used in this regard.
Mohammad Alidousti, Gholamreza Davoodi,
Volume 4, Issue 1 (7-2004)
Abstract
Background: Obesity is associated with many metabolic and cardiovascular diseases, for example, a direct and indirect relation has been established between obesity and diabetes, dyslipidemia, hypertension and atherosclerosis. But whether regional fat distribution contributes independently to risk remained unclear. This study was designed to determine relation between central obesity and acute myocardial infarction (AMI).
Methods: In this case-control study, body mass index (BMI) and waist to hip ratio (WHR) were calculated in 420 participants (140 cases and 280 controls). BMI and WHR means were evaluated in subgroups according to age, sex and cardiac risk factors. Odds ratio (95% CI) of the MI incidence in obese participants (BMI≥27 and/or WHR≥0.85) were compared with non obese subjects in each subgroups.
Results: Mean BMI mean in the case group (27.9±4.9) was more than control group (25.8±4.9) P≤0.05). The obese individuals had more chance of AMI (OR=3.2 CI=3-3.3). This chance increased with central obesity (OR=3.4 CI=3.2-3.6). Risk of AMI in younger obese participants (OR=4.3 CI=2.8-6.8) was more frequent than older ones (OR=2.1 CI=1.7-2.4). Central obesity increased risk of AMI in women (OR=3.6 CI=3.1-4.4) more than men (OR=2.2 CI=1.7-2.5).The excess risk of AMI in obese participants in associated with major cardiac risk factors was as following: hypertension (OR=18.4 CI=9.8-22.1), diabetes (OR=9 CI=4.2-14.1), hyperlipidemia (OR=6 CI=2.1-8.4), positive familial history (OR=2.6 CI=2.1-3.4) and smoking (OR=1.2 CI=0.9-1.7).
Conclusion: There is a strong association between BMI, WHR and risk of AMI. Central obesity comparing with general obesity has stronger relation with AMI incidence especially in women and younger subjects. In addition, cardiac risk factors except smoking aggravated correlation between obesity and AMI.
Reza Rajabian, Mohammad Khajedeluee, Afsoon Fazlinejad, Javad Rezazadeh,
Volume 4, Issue 4 (6-2005)
Abstract
Background: Myocardial infarction is the most important cause of mortality all over the world. Complications may increase with some risk factors including stress hyperglycemia. The aim of this study was to evaluate the correlation and importance of hyperglycemia in acute intrahospital complications after AMI.
Methods: Prevalence of stress hyperglycemia among 160 patients with acute myocardial infarction (Q wave MI) was determined. These patients were divided into normoglycemic and stress hyperglycemic groups. These were compared according to complications such as heart failure, cardiogenic shock and mortality.
Results: 61% were normoglycemic and 7.5% had stress hyperglycemia. 25% had history of diabetes and 4.4% were not aware of diabetes. Among 18 patients with stress hyperglycemia, 6 patient (50%) and among 101 normoglycemic patients 18 (17.8%) were affiliated with cardiac failure that the difference were significant (P=0.02 and χ 2= 6.25). There were no cases of cardiogenic shock in both groups. Three patients died during first hours of admission (2.97%). They hadn't have history of diabetes. We could not assign them to normoglycemic or stress hyperglycemic groups since blood sampling had not been done yet.
Conclusion: Stress hyperglycemia can increase complications of AMI, significantly stress hyperglycemia caused increased incidence of heart failure in this study.
