Trust is one of the most important aspects of human relationships, providing the foundation for participation and cooperation among individuals. It is also one of the most valuable social assets within the healthcare system. If trust is disrupted, it can impose significant costs on the system. The purpose of this study is to measure the level of patients' trust in doctors and its impact on the treatment process at Shahid Beheshti Hospital, Kashan. In this study, 325 patients referred to the emergency department of Shahid Beheshti Hospital in Kashan were selected. After applying the inclusion and exclusion criteria, 310 participants remained in the study. The General Trust Instrument was used for this research. This questionnaire consists of 33 questions covering six dimensions: patient-centered care (6 questions), macro-level patient care policies (6 questions), provider expertise (4 questions), quality of care (9 questions), communication and information provision (6 questions), and quality of collaboration between providers (2 questions). Scores ranged from 0 to 100, categorized as follows: 0–20 indicates very low trust, 20–40 low trust, 40–60 moderate trust, 60–80 high trust, and 80–100 very high trust in healthcare. Out of the 310 participants, 157 (50.6%) were male, and 153 (49.4%) were female. The mean age of the patients was 56.6 ± 20.6 years. Among the patients, 178 (57.4%) had acute illnesses, while 132 (42.6%) had chronic illnesses. The mean and standard deviation of the total score for the General Trust Questionnaire was 95.59 ± 13.8. This study demonstrated that the general trust score of patients in the doctors at this center is high. In delivering healthcare, interventions alone are insufficient; improving the quality of services is essential to enhance patient trust and satisfaction.