A Mahmoudlou, P Yavari, F Abolhasani, A Khosravi, R Ramazani,
Volume 9, Issue 4 (3-2014)
Abstract
Background and Objectives: Colorectal cancer, as the third common cancer, is one of the main health problems in Iran. We assessed the burden of colorectal cancer, as one of the high-priority indices, in this cross-sectional study in Iran in 2008.
Methods: CANMOD software was used for calculation. The input data included the population of Iran, all-cause and colorectal cancer mortality rates, and incidence rate of colorectal cancer, which were all obtained from the Iran Statistic Center, Mortality Registry System, and Cancer Registry System.
Results: The total burden of colorectal cancer according to DALY in Iran in 2008 was 52534 years in the total population. Years of lost life (YLL) amongst males and females were 26455 and 19887 years, respectively. Years lived with disability (YLD) were 3473 and 2719 years for males and females, respectively. The burden of colorectal cancer per 1000 population was 75.4 years for males and 65.7 years for females. The peak age of colorectal cancer burden rate was in the age group 45-79 years.
Conclusion: The burden of the colorectal cancer in Iran has increased compared to the last study (2003) which is due to the increase in its incidence and the related mortality during this period. Due to the possibility of prevention and effective intervention, this cancer should be a priority in the health care system. However, the final judgment should be made after calculation of the burden of other cancers, diseases, and damages at the country level and their respective rankings.
T Rezagholi, P Yavari, F Abolhasani, K Etemad, A Khosravi, Ss Hashemi Nazari , A Mahmoudlou,
Volume 10, Issue 4 (Vol 10, No 4 2015)
Abstract
Background and Objectives : Breast cancer is the second most common cancer among Iranian women. The peak age of breast cancer in Iran is one decade lower than the global estimates. The aim of this cross-sectional study was to estimate the burden of breast cancer in Iranian women in the country level.
Methods: In this study, the CANMOD software was used for the calculation of DALYs as the sum of YLL and YLD. The required data was the population of the Iranian women, mortality due to breast cancer, incidence cases of breast cancer, and mean time of the stages of breast cancer that was obtained from the Mortality Registry System, Cancer Registry System, and expert panel views .
Results : In this study, the total burden of breast cancer in Iranian women was 75811 years in 2009. Moreover, the years of life lost (YLL) was 54938 years while years lived with disability (YLD) was estimated 20873 years. The rate of DALYs per 100000 female population was 220.9 years. The peak age of breast cancer burden was in the age group 45-59 years. The incidence to mortality ratio was 3/2.
Conclusion: The incidence rate, mortality rate, and the burden of breast cancer in Iranian women increased in 2009 when compared to a previous study in 2003. The findings of this study may provide Iranian health managers with some information on the determinants of the burden of breast cancer in order to design preventive measures as well as screening programs for early detection of breast cancer.
Mohammad Zare, Zahra Tagharrobi, Khadijeh Sharifi, Zahra Sooki, Javad Abolhasani,
Volume 17, Issue 2 (Vol 17,No.2, Summer 2021 2021)
Abstract
Background and Objectives: Valid, reliable, short, sensitive and accurate tool is needed to diagnose pain in dementia patients. This study aimed to determine the psychometric properties and diagnostic accuracy of short-form Persian version of Doloplus-2 (P-Doloshort) in pain assessment in elderly with dementia.
Methods: In this cross-sectional study, 100 elderly were selected using convenient sampling from private clinics and nursing homes in Kashan in 2018-19. Construct validity was determined by exploratory factor analysis, known-groups approach and convergent validity. Also, reliability was evaluated by internal consistency, equivalence, and stability. P-Doloplus-2 and P-Doloshort were used as the reference standard and the index test, respectively. Data were analyzed by SPSS-v16 using independent T-Test, linear regression, Pearson and intra-class correlation coefficients (ICC), Cronbach's alpha, ROC curve, and diagnostic test parameters.
Results: Factor analysis identified the tool as a single-factor; it was able to explain 65.851% of total variance. P-Doloshort was able to differentiate between two groups with and without painful underlying diseases (P<0.0001). There was a positive and significant correlation between P-Doloshort score with P-Doloplus-2 score (r=0.975, P<0.0001) and PACSLAC-II-IR score (r=0.0001, P<0.0001). Cronbach's alpha, ICC and standard error of measurement were 0.898, 0.891 and ±1.183, respectively. The relative frequency of minimum and maximum possible score was less than 15%. At the cut-off point of 2.5, area under ROC curve, sensitivity, specificity, and overall diagnostic accuracy were estimated 0.985, 0.956, 1.000 and 0.970, respectively.
Conclusion: P-Doloshort can be used as a valid, reliable, sensitive and accurate tool for pain assessment in elderly with dementia.
Zahra Jafarabadi, Farid Abolhasani, Mohammad Hassan Lotfi, Hossein Fallahzadeh,
Volume 18, Issue 2 (Vol.18, No.2, Summer 2022 2022)
Abstract
Background and Objectives: Colorectal cancer is the second and fourth most common cancer in Iranian women and men, respectively. This cancer ranks fourth and fifth in men and women, respectively, among Yazd population. This study aimed to estimate the burden of colorectal cancer in Yazd province in 2016.
Methods: This descriptive cross-sectional study was performed on the population of Yazd province in 2016. CanMod software was used to calculate the burden of colorectal cancer. The required information included the population of Yazd province, the incidence of colorectal cancer, the death rate due to colorectal cancer, the death rate due to all causes and the survival rate of patients; The Cancer Registration System, the Provincial Death Registration System and the opinions of provincial experts were collected and included, respectively.
Results: The total burden of colorectal cancer in Yazd province was 632 years (382 years in men and 250 years in women); The YLL and YLD of colorectal cancer in both genders were 478 years and 154 years, respectively. The burden of colorectal cancer in men was 65 years and in women 45 years (per 100,000 population). The peak age of disease burden was estimated in the age group over 60.
Conclusion: Due to the high incidence and treatment in the early stages of the disease, screening and diagnosis in the early stages can be one of the health priorities of the province. However, the final judgment is made when the burden of other diseases and injuries is calculated in the province.
