Showing 3 results for Amirian
Azizi A, Amirian F, Amirian M,
Volume 4, Issue 3 (20 2009)
Abstract
Background & Objectives: The youth group is more prone to HIV infection. Education is a cornerstone to prevention. This study was conducted to compare the efficacy of peer education and traditional lectureship and distribution of pamphlet on high school students.
Methods: 1500 female high school students, third graders, were selected based on stratified random sampling studying in 21 high schools in Kermanshah. In each high school, 73 third grades were selected as the sample of the study. We designed a questionnaire as an assessment tool for interventions. Peer education was done by 502 students, and AIDS awareness pamphlet was distributed on 500 students, and the rest of students were attended a one-day workshop which was ran by a female physician in their high school.
Results: The mean average age was 16.78 (SD= ± 0.7) years. The mean scores of pretest and post-test in each groups were statistically significant different (P=0.0001). Mean score of difference in workshop by female physician was greater than peer education group, 10.7 and 8.8, respectively. The group whome received their knowledge about AIDS by pamphlet obtained the least mean score than other groups and this was statistically significant (P=0.0001).
Conclusions: The findings of this study indicate that educating students by general practitioners is more effective way to increase students’ knowledge about prevention of AIDS.
M Amini, A Kazemnejad, F Zayeri, A Amirian, N Kariman,
Volume 16, Issue 1 (Vol.16, No.1 2020)
Abstract
Background and Objectives: Gestational diabetes mellitus (GDM) is a medical problem in pregnancy, and its late diagnosis can cause adverse effects in the mother and fetus. The purpose of this research was to estimate the accuracy parameters of a biomarker for early prediction of gestational diabetes in the absence of a perfect reference standard test.
Methods: This study was conducted in 523 pregnant women who presented to Mahdieh Hospital and Taleghani Hospital affiliated with Shahid Beheshti University of Medical Sciences, Tehran, Iran 2017-2018. As a predictor for detecting GDM, beta- human chorionic gonadotropin (β-hCG) measurements were recorded during 14-17th weeks’ gestation in a checklist. The Bayesian latent variable model was used to estimate the sensitivity, specificity, and area under receiver operating characteristic curve (AUC). Bayesian parameter estimation was calculated using the R2OpenBUGS package in R version 3.5.3.
Results: The median gestational age was 33 years. In the absence of a perfect reference test, the applied model had a sensitivity, specificity, and AUC of 78% (95% credible interval (CrI): 0.66-0.83), 83% (95% CrI: 0.74-0.89), and 0.72 (95% CrI: 0.64-0.88) for β-hCG, respectively.
Conclusion: According to the results of this study, β-hCG may be an acceptable biomarker for early diagnosis of diabetes in pregnant women in the absence of a perfect reference test.
Marzieh Gharanjiki, Abdolhalim Rajabi, Taghi Amiriani, Gholamreza Roshandel, Mohammadali Vakili,
Volume 21, Issue 2 (Vol.21, No.2, Summer 2025)
Abstract
Background and Objectives: Colorectal cancer is the most common gastrointestinal malignancy worldwide, and its incidence is increasing in Iran. Competing risk analysis offers a refined approach to identify factors influencing Colorectal cancer-specific mortality. Therefore, This study was designed and conducted to determine the survival of patients with colorectal cancer and its associated factors.
Methods: The study was a historical cohort. Data of patients diagnosed with colorectal cancer between 2013 and 2019 at Golestan University of Medical Sciences were collected, and patients were followed up until May 4, 2024. Patient survival was estimated, and the cumulative incidence function, as well as competing risk models of cause-specific hazards and subdistribution hazards, were applied for competing risk analysis. Model adequacy was assessed using the Akaike Information Criterion. Analyses were performed in STATA version 17 (α = 0.05).
Results: Of the 811 patients, 366 (45.13%) were women and the rest were men. The mean age and standard deviation were calculated as 58.54 ± 13.87 years. In the multivariable analysis of factors associated with colorectal cancer mortality in the presence of competing risks, variables including gender, age, literacy, ethnicity, and metastasis were statistically significant in both models. Findings indicated that the cause-specific hazard model provided a better fit for analyzing survival outcomes in colorectal cancer.
Conclusion: Competing risk analysis based on cause-specific hazards is recommended in the multivariable analysis of factors associated with colorectal cancer mortality, particularly in the presence of competing risks of death from other causes.
