Showing 2 results for Athari Nik Azm
S Athari Nik Azm, Mr Vafa, I Nourmohammadi, A Bidari, A Hoshyarrad, Sh Jazayeri, F Hoseini, M Fasihi Radmandi,
Volume 5, Issue 3 (20 2009)
Abstract
Background & Objectives: oxygen free radicals have been implicated as mediators of tissue damage in RA patients. This study was aimed to find the effects of vitamin A, C and zinc supplementations on oxidant–antioxidant, inflammatory and clinical indices in inactive RA patients.
Methods: We designed a randomized controlled trial. Forty nine (49) patients were randomly allocated in two groups group I received their conventional treatment plus 300 mg vitamin C, 5 mg Zinc daily and 25000 IU vitamin A every other day for 12 weeks, group II received their conventional treatment only for the same duration. Disease activity (using the rheumatoid arthritis disease activity index (RADAI) score), biochemical indices [malondialdehyde (MDA), total antioxidant capacity (TAC)] and inflammatory markers [erythrocyte sedimentation rate (ESR), c-reactive protein (CRP)] was evaluated before and after 12 weeks.
Results: Serum concentration of MDA and RADAI score (P<0.0001) and ESR (P=0.033) were significantly decreased and TAC levels (P<0.0001) were significantly increased in the first group in comparison to second group after 12 weeks. However, there were no statistically significant differences in serum CRP concentration of two groups (P>0.05).
Conclusions: This study indicates that adding antioxidants as supplementations with conventional medications in inactive RA patients plays an important role in improving oxidative stress and decreasing disease activity and inflammatory status.
H Sabour, A Norouzia Javidan, Mr Vafa, F Shidfar, M Nazari, S Athari Nik Azm, A Rahimi, H Emami Razavi, H Saberi,
Volume 7, Issue 1 (20 2011)
Abstract
Background & Objectives: Despite an increased risk of obesity and CHD in people with spinal cord injury (SCI),
there is little known about the dietary intake in this group, therefore the aim of this study was to examine nutrient
intake and body mass index (BMI) in the spinal cord injury (SCI) population according to level of injury and
related variables.
Methods: In this cross-sectional study, 162 patients with spinal cord injury participated from Brain and Spinal
Injury Repair research Center, Tehran, Iran. Dietary intakes were assessed by means of a semi quantitative food
frequency questionnaire.
Results: The mean age of study population was 34.1±0.6 years. Total energy and carbohydrate intake were
higher in men than women (P<0.001). Incomplete injured consumed more MUFA (P=0.03). The elderly were
consumed less total calorie, saturated fat, MUFA, cholesterol (P<0.01) and PUFA (P<0.05). Injured patients with
longer times had lower total calorie, carbohydrate (P<0.01), total fat and MUFA intake (P<0.05). Based on new
classification 60.5% were at the risk of obesity or obese. Central obesity was seen in 33.1%of man and 48.4%
of women. BMI of the paraplegia group was greater than that of the tetraplegia group (P= 0.009).
Conclusion: Macronutrients balance is moved towards higher saturated fat intake and less complex
carbohydrates and protein intake in SCI patient’s .The elderly and patients who had lived with SCI longer time
tended to maintain healthier diets.
