S Mehdipour, F Zolala, M Hoseinnejad, R Zahedi, E Najafi, M , N Farrokhnia, M Fathi,
Volume 14, Issue 2 (Vol.14, No.2, 2018)
Abstract
Background and Objectives: Evidence suggests that underlying diseases increase the severity of influenza and lead to hospitalization or death. This study was conducted to determine the risk factors associated with hospitalization of patients in Afzalipour Hospital, Kerman, Iran during an outbreak of H1N1 influenza in December 2015.
Methods: In this case-control study, the case group comprised 85 patients who were hospitalized for influenza and the control group included 51 patients who had influenza symptoms and were discharged after required evaluations and check-up. The data were collected from both groups on a daily basis for two weeks. For data analysis, descriptive analysis, logistic regression analysis, Lasso Regression, and likelihood ratio were used. Analysis was performed using the Stata version 12 and R software.
Results: Among the variables examined, after removal of additional variables, 12 variables were introduced into the multivariate regression. The history of pulmonary disease and diabetes increased the odds of hospitalization following influenza by more than 11 (OR = 11.6, P. value = 0.003) and 9 times (OR = 9, P. value = 0.01), respectively.
Conclusion: Underlying disease and factors play a major role in exacerbating the disease. Therefore, the health system should take the necessary preventive measures when outbreaks occur.
Ali Esmaeilpour, Parya Jangipour Afshar, Nouzar Nakhaee, Mehrdad Farrokhnia, Aliakbar Haghdoost,
Volume 20, Issue 1 (Vol.20, No.1, Spring 2024)
Abstract
Background and Objectives: This study aimed to evaluate the relationship between the COVID-19 severity and lifestyle among hospitalized patients at Afzali Pour Hospital, Kerman, Iran.
Methods: A total of 289 patients with severe COVID-19 infection (with ICU admission or death) and 293 patients with non-severe type (discharged with no need for hospitalization in ICU) were selected in 2020-2021, and their lifestyle was compared in the last year before the hospitalization.
Results: The adjusted odds ratio (AOR) for severe disease was 1.83 (95% CI: 1.24-2.69) in males compared to females, and 4.35 (95% CI:2.20- 8.59) for people older than 60 years compared to age less than 60. The linear effect of average hours of sleeping during a day was 1.21 (95% CI: 1.08-1.36). The ORs of people who had considerable physical activity at work and people with little activity compared to people who mostly sit in a fixed place were 0.35 (95% CI:0.19-0.65) and 0.44 (95% CI:0.23-0.83), respectively. The use of opioids, traditional remedies, and supplements such as vitamin C raised the risk of severe disease, but the use of vitamin D supplements reduced the risk of severe disease, although this was not statistically significant.
Conclusion: It seems that some aspects of lifestyle, such as lack of physical activity, excessive sleep, and consumption of certain substances, such as opioids, might increase the risk of contracting severe and deadly forms of COVID-19.
