N Khodakarami, Sj Hosseini, P Yavari, F Farzaneh, K Etemad, S Salehpour, M Sohanaki, N Broutet, P Jf Snijders, G Clifford, S Franceschi,
Volume 7, Issue 4 (16 2012)
Abstract
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Background & Objectives: Human papillomavirus (HPV) infection seems to be the
most common sexually transmitted infection. High-risk (HR) human papillomavirus
(HPV) prevalence has been shown to correlate well with cervical cancer
incidence rates. Since there is little known about the epidemiology of this
infection in Tehran, we designed to estimate the prevalence of HPV in some
areas in Tehran.
Methods: Cervical
specimens were obtained from 825 married women aged 21-59 years from the
general population of Tehran, Iran according to the standardised protocol of
the IARC International HPV surveys. HPV was detected using a GP5+/6+ PCR-based
assay.
Results: HPV
prevalence in the general population was 7.8% (5.1% of high-risk types), with
no statistically significant variations by age. Cervical intraepithelial
neoplasia was diagnosed in 4.1% of women, of whom 35.3% were HPV-positive.
HPV16 was confirmed as the most common type among women with both normal (1.8%)
and abnormal (8.8%) cytology. HPV positivity was significantly higher among divorced
women, women in polygamous marriages and those reporting husbands' extramarital
affairs.
Conclusion: However
the prevalence of HPV seems not high in comparison with other international
data, more molecular and seroepidemiological survey in national level needs to
have a better perspective.
Reza Dehnavyeh, Mohammad Jaafari Sirizi, Vahid Yazdi Feyzabadi, Farzaneh Yousefi, Parisa Dehghanian,
Volume 20, Issue 3 (Vol.20, No.3, Autumn 2024)
Abstract
Background and Objectives: Paying attention to future changes and preparing for them is one of the requirements of today's world. Personalized medicine as an emerging and expanding change will bring about changes in medical science. Family physicians as the first line of service delivery and health insurance as factors affecting the provision of services will face this issue. The aim of this study was to draw the space for applying this approach in the field of family physicians and the changes it will bring.
Methods: This study has three stages: preparing a presentation file about personalized medicine and formulating questions, holding a meeting with family physicians, completing the questions form as a group, presenting their opinions, and finally, analyzing and summarizing the views of the doctors by the research team.
Results: Implementing personalized medicine will positively affect each of the family physician's functions, including health management, comprehensiveness of services, continuity of service delivery, coordination, and research. However, like any new change in any field, implementing this approach in this part of the health system will be challenging. There are solutions to face these changes and the resulting challenges from the point of view of family doctors.
Conclusion: As one of the essential parts of facing the changes in the health field, family physicians and health insurance should monitor the issues of this field prospectively and prepare themselves to face them. Providing infrastructures according to possible challenges and considering the principles of change management can be a solution for effectively implementing this approach in this field.
