M Amini, A Kazemnejad, F Zayeri, A Amirian, N Kariman,
Volume 16, Issue 1 (Vol.16, No.1 2020)
Abstract
Background and Objectives: Gestational diabetes mellitus (GDM) is a medical problem in pregnancy, and its late diagnosis can cause adverse effects in the mother and fetus. The purpose of this research was to estimate the accuracy parameters of a biomarker for early prediction of gestational diabetes in the absence of a perfect reference standard test.
Methods: This study was conducted in 523 pregnant women who presented to Mahdieh Hospital and Taleghani Hospital affiliated with Shahid Beheshti University of Medical Sciences, Tehran, Iran 2017-2018. As a predictor for detecting GDM, beta- human chorionic gonadotropin (β-hCG) measurements were recorded during 14-17th weeks’ gestation in a checklist. The Bayesian latent variable model was used to estimate the sensitivity, specificity, and area under receiver operating characteristic curve (AUC). Bayesian parameter estimation was calculated using the R2OpenBUGS package in R version 3.5.3.
Results: The median gestational age was 33 years. In the absence of a perfect reference test, the applied model had a sensitivity, specificity, and AUC of 78% (95% credible interval (CrI): 0.66-0.83), 83% (95% CrI: 0.74-0.89), and 0.72 (95% CrI: 0.64-0.88) for β-hCG, respectively.
Conclusion: According to the results of this study, β-hCG may be an acceptable biomarker for early diagnosis of diabetes in pregnant women in the absence of a perfect reference test.
F Rashidi Fakari, Fa Rahnemaei, Z Kiani, F Rashidi Fakari, M Ghazanfarpour, N Kariman,
Volume 17, Issue 4 (Vol.17, No.4, Winter 2022 2022)
Abstract
Background and Objectives: In most parts of the world, pelvic girdle and lower back pain are one of the most common musculoskeletal disorders, but its prevalence has been reported differently in studies around the world. were performed to investigate the-analysis Therefore, the present meta prevalence of pelvic girdle and lower back pain in pregnant women.
Methods: all articles published from 2005 to May 2020 using the keywords Pelvic Girdle Pain, Low back pain, Cross-Sectional, Prevalence, Epidemiology, Survey in Scopus, PubMed, Web of Science Core Collection,Science Direct and SID collected and reviewed. Munn et al. tools were used to evaluate the quality of studies and methodology.
Results: 26 studies with a sample size of 13430 showed that, the overall prevalence of pelvic girdle and low back pain in pregnant women is 50% (95% CI: 43-58%, I2: 98.9%) and in primigravida women 44% (95% CI: 35-54%, I2: 97.9). Also, the prevalence of pelvic girdle and low back pain was using the questionnaire 57% (95% CI: 47-68, I2: 99.04%), using a combination of methods 53% (95% confidence interval: 37-70, I2: 96.12%), using a VAS Scale 38%(95% confidence interval: 23-52, I2: 99.08%).
Conclusion: The results of the present study indicate a 50% prevalence of pelvic girdle and low back pain in pregnant women. Due to the high prevalence and effects of pain on the quality of life of pregnant women, it seems necessary to plan, policy and design effective interventions in this field by the treatment team.
