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S Masudi, Y Mehrabi, D Khalili, P Yavari,
Volume 11, Issue 4 (Vol 11, No.4, Winter 2016 2016)
Abstract

In epidemiologic studies, the measurement of characteristics of interest is almost always subject to random measurement error. This error and its effects are usually overlooked by researchers. One of its effects is a widespread statistical phenomenon that is well known as regression to the mean. This phenomenon occurs whenever an extreme group of people is selected from a population based on their measurements of a variable. If a second measurement is taken in this group, the mean of the second measurement will be closer to the mean of the population.  In interventional studies, this increase (decrease) might be regarded as the effect of intervention, when in fact it has had no effect. Ignoring regression to the mean will lead to the erroneous conclusions and interpretation of the results of epidemiologic studies and affects the decisions in evidence-based medicine and planning for preventive and public health measures. This paper highlights the importance of this problem and its effects in epidemiologic studies and the ways to avoid it.


Fatemeh Rostampour, Hamid Reza Khalkhali, Sima Masudi,
Volume 19, Issue 3 (Vol.19, No.3, Autumn 2023)
Abstract

Background and Objectives: Animal bites are one of the most important public health problems that cause rabies. This study aimed to investigate the preventive measures taken for animal bite cases that occurred in West Azerbaijan province during 2012 to 2019.
Methods: This cross-sectional study involved the review data from all animal bite cases referred to rabies care centers in West Azerbaijan province. Information regarding prophylactic measures to prevent rabies, including post-bite procedures (washing, disinfection, dressing, stitches and receiving antibiotics), anti-rabies vaccine status (referral delay, vaccine dose received, vaccination history, anti-rabies serum, tetanus vaccination history) was analyzed using descriptive statistics. The relationship between delay in referral and the measures taken was investigated using the Chi-square test.
Results: Over the studied years, there were 47131 cases of animal bites. Among these, 63.9% were referred without delay, while 36.1% experienced a delay in referral. Notably, 99.6% of wounds were washed with soap and water, 94.5% were disinfected, and 31.3% received antibiotics. The proportion of individuals receiving antibiotics was significantly higher among those with delayed referrals. Regarding rabies vaccination, 77.3% had received all three initial doses, 15.4% had completed five doses, and 1.1% had not received any vaccine.
Conclusion: While prophylaxis measures for animal bite cases are commendable, there is a critical need for timely administration of rabies vaccine in rabies care centers. Implementing educational programs for general population to encourage prompt treatment-seeking in the event of animal bites is essential.


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