Aa Akhlaghi, M Hosseini, M Mahmoodi, M Shamsipour, E Najafi,
Volume 8, Issue 2 (9-2012)
Abstract
Background & Objectives: Peritoneal
dialysis is one of the most common types of dialysis in patients with renal
failure. However multivariate analysis such as log- rank test and Cox have
usually used to evaluate association of risk factors in survival of this group
of patients, the aim of this study was to perform of Weibull, Gamma, Lognormal and
Logistic Mixture cure models in survival analysis of these patients.
Methods: Data
of 433 patients undergoing CAPD who registered in two centers in Tehran, Iran
between 1997 to 2009 were used in this analysis. We investigated center,
gender, age, cholesterol, Low Density Lipoprotein (LDL), High density
lipoprotein (HDL), triglyceride, albumin, hemoglobin, creatinine, Fasting Blood
Sugar (FBS), calcium and phosphorous as variables effect with Kaplan-Meier and
cure model. CUREREGR module was used for survival analysis.
Results: Comparison
of AIC (Akaike Information Criterion) of Weibull, Gama, Lognormal and Logistic
Mixture cure models showed that Weibull distribution AIC is lower for almost
all variables than other distributions. Weibull distribution has better fitness
for data than others. In the multivariate Weibull model, age and albumin
variables had significant effect on long-term survival of patients (P<0.01).
Triglycerides effect on long-term survival had borderline (P = 0.065). Also
HDL, FBS and calcium were significant on short term survival (P<0.01) but
significance of LDL was borderline (P=0.088).
Conclusion: Cure models have the ability to analyze
dialysis patients' survival data and can differentiate long-term survival from short-
term survival. The interpretation of survival data with these statistical
models could be more accurate and would help to make better prediction for
patients by health care professionals.
M Cheharazi, M Shamsipour, M Norouzi, F Jafari, F Ramazan Ali,
Volume 8, Issue 2 (9-2012)
Abstract
Background & Objectives: One of the problems of diagnostic accuracy studies is
verification bias. It occurs when standard test performed only for
non-representative subsample of study subjects that diagnostic test done for
them. In this study we extend a Bayesian method to correct this bias.
Methods: Patients
that have had at least twice repeated failures in cycles IVF ICSI were included
in this model. Patients were screened by using an ultrasonography and those
with polyps recommended for hysteroscopy. A logistic regression with binomial
outcome fit to predict the missing values (false and true negative),
sensitivity and specificity. Bayesian methods was applied with informative
prior on polyp prevalence. False and true negatives were estimated in Bayesian
framework.
Results: A
total of 238 patients were screened and 47 had polyps. Those with polyps are
strongly recommended to undergo hysteroscopy, 47/47 decided to have a
hysteroscopy and 37/47 were confirmed to have polyps. None of the 191 patients
with no polyps in ultrasonography had hysteroscopy. The false negative was
obtained 14 and true negative 177, so sensitivity and specificity was estimated
easily after estimating missing data. Sensitivity and specificity were equal to
74% and 94% respectively.
Conclusion: Bayesian analyses with
informative prior seem to be powerful tools in simulation experimental
A Saki Malehi, E Hajizadeh, R Fatemi,
Volume 8, Issue 2 (9-2012)
Abstract
Background
& Objectives: Identifying
the important influential factors is a great challenge in oncology studies.
Decision tree is one of methods that could be used to evaluate the prognostic
factors and classifying the patients' homogeneously. This method identifies the
main prognostic factors and then determines the subgroups of patients based on
those prognostic factors. The aim of this study was to assess the prognostic
factors and homogeneous subgroups of colorectal patient through survival tree.
Methods: Data collected from an observational
of 739 colorectal patients registered in the cancer registry affiliated to the
center of Research Center of Gastroenterology and Liver Disease (RCGLD), Shahid
Beheshti Medical University, Tehran, Iran. Death was the interested event and
the survival time was calculated from date of diagnosis until occurrence of
event (or censoring) in months. Finally we used decision tree based method for
classifying and analyzing the data.
Results: Based on our result, decision tree
identified four covariates as important prognostic factors in 0.05 significant
levels: general stage of cancer, age of diagnosis, histology of tumor and
morphology type of tumor. Also patients based on these prognostic factors
divided into five homogeneous subgroups. The greater values of measure of
separation (SEP) criterion support the appropriateness of this model for such
the data.
Conclusion:
Decision tree is powerful and intuitive method. It has a key feature that is in
addition to evaluate the prognostic factors, provides the homogeneous subgroups
for future analysis.
A Kassani, M Gohari, M Mousavi, M Asadi Lari, M Rohani, M Shoja,
Volume 8, Issue 2 (9-2012)
Abstract
Background and Objectives: Social capital consists of
individuals' communicational networks, social norms such as mutual trust and
cooperation in social networks. The aim of this study was to develop a model to
assess the implication of different determinants such as age, gender,
occupational status, mental and physical health on social capital components to
draw a correlation network for social capital determinants.
Methods: For the purpose of this study, data
was used from ‘social capital' section of Urban HEART-1 survey, which included
22,500 households from all 22 districts of Tehran, who were approached in a
randomized multistage cluster sampling method. Path analysis is a statistical
method to test hypothetical causal models, which requires various causal (path)
diagrams. To demonstrate the causal models of social capital, the hypothetical
paths of various components were developed and the final model of social
capital was drawn using multiple regression analyses.
Results: Path analysis indicated that social
capital components are influenced by various variables: A) Individual trust, by
occupational status, marital status, and physical component of health-related
quality of life B) Cohesion and social support, by education, age, and marital
status C) Collective trust and associative relation, by family size, age and
physical health. Direct effect of these variables on social capital components
was more than their indirect effects (through mental health and physical
health).
Conclusion: Social capital components
are directly affected by occupational, marital, educational status, family
size, physical health and duration of local residency. Planning to improve
educational and occupational status, strengthening family bonds and provision
of local facilities, may improve social capital.
N Mahdavi, M Movahedi, A Khosravi, Y Mehrabi, M Karami, ,
Volume 8, Issue 3 (12-2012)
Abstract
Background and Objectives: Due to the importance of mortality
statistics for planning, setting priorities and equal allocation of health
services in population it is essential to assess quality of reporting
mortality data in health systems. The aim of this study was to evaluate the
completeness and accuracy of the Iranian Vital Horoscope reports for maternal
and the under-five mortality (U5M) in rural areas through its comparison with
other data sources in Iran.
Methods: The mortality data of Vital
Horoscope reported from 30 selected cities over country was compared with the
related data obtained from other data sources including Vital Horoscope's
Fieldwork reports, Death Registration System and Maternal Mortality
Surveillance System of Ministry of Health and Medical Education.
Results: Overall completeness of Vital
Horoscope's Fieldwork reports for U5M in rural areas was about % 62.1. In terms
of cause of death in children under-five,estimated sensitivity values were %
47.2 (95% CI: 22.9-72.2), % 66.6(95% CI: 22.7-95.7), %78.2 (95% CI: 64.3-89.3)for respiratory
infections, diarrhea and vomiting, and injuries-burning and poisoning respectively.
The vital horoscope reports had 12.5% misclassification in determining the cause of maternal death.
Conclusion: Our findings indicate the Vital Horoscope's data might
need some corrections because of underestimating of the mortality indicators.
The comparison of this source with Death Registration System report for causes
of death in children under-five (reported by Vital Horoscope) suggests that the
vital horoscope might have suboptimal quality.
Normal
0
false
false
false
EN-US
X-NONE
AR-SA
N Mahdavi, M Movahedi, A Khosravi, Y Mehrabi, M Karami,
Volume 8, Issue 3 (12-2012)
Abstract
Background and Objectives: Due to the importance of mortality statistics for planning, setting priorities and equal allocation of health services in population it is essential to assess quality of reporting mortality data in health systems. The aim of this study was to evaluate the completeness and accuracy of the Iranian Vital Horoscope reports for maternal and the under-five mortality (U5M) in rural areas through its comparison with other data sources in Iran.
Methods: The mortality data of Vital Horoscope reported from 30 selected cities over country was compared with the related data obtained from other data sources including Vital Horoscope's Fieldwork reports, Death Registration System and Maternal Mortality Surveillance System of Ministry of Health and Medical Education.
Results: Overall completeness of Vital Horoscope's Fieldwork reports for U5M in rural areas was about % 62.1. In terms of cause of death in children under-five,estimated sensitivity values were % 47.2 (95% CI: 22.9-72.2), % 66.6(95% CI: 22.7-95.7), %78.2 (95% CI: 64.3-89.3)for respiratory infections, diarrhea and vomiting, and injuries-burning and poisoning respectively. The vital horoscope reports had 12.5% misclassification in determining the cause of maternal death.
Conclusion: Our findings indicate the Vital Horoscope's data might need some corrections because of underestimating of the mortality indicators. The comparison of this source with Death Registration System report for causes of death in children under-five (reported by Vital Horoscope) suggests that the vital horoscope might have suboptimal quality.
M Karami, H Soori, Y Mehrabi, Aa Haghdoost, Mm Gouya,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: Knowledge of the presence of seasonal trends and other explainable patterns in the prediagnostic data sources and removing such patterns before applying outbreak detection methods seem very important. This study aimed to detect and remove the explainable patterns such as seasonality, day-of-week (DOW) and holiday effects of the daily counts of suspected cases of measles in Iran.Methods: Data on daily counts of suspected cases of measles as a pre-diagnostic data source were obtained from Iranian national surveillance system between 21 March 2008 and 20 March 2011. We used lines plot, moving average chart, autocorrelation and partial autocorrelation functions for detecting explainable patterns. Moving average (MA) and Holt- Winters (HW) exponential smoothing method are used for removing explainable patterns.
Results: Our findings indicate the presence of seasonality, DOW effect, holidays and weekend effects in the daily counts of suspected cases of measles. The good performance of HW exponential smoothing technique in removing seasonal patterns is evident. MA technique showed better performance regarding assumption violation on outbreak detection methods.
Conclusion: Because of the presence of explainable patterns in the daily counts of suspected cases of measles, considering such patterns before applying outbreak detection algorithms is very important. Implementing both MA (7 days) techniques for its simplicity as a pre- processing method and HW method for its efficacy in removing seasonal patterns is recommended.
M Karami, H Soori, Y Mehrabi, Aa Haghdoost, Mm Gouya,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: Evaluating the performance of outbreak detection methods using real data testing provide the highest degree of validity. The aim of this study was to determine the performance of the Exponentially Weighted Moving Average (EWMA) in real time detection of two local outbreaks in Iran.
Methods: The EWMA algorithm (both ƛ= 0.3 and 0.6) applied on daily counts of suspected cases of measles to detect local outbreaks which had been occurred in Mashhad and Bandar Abbas cities during 2010. The performance of The EWMA algorithms were evaluated using real data testing approach and reported by correlation analysis.
Results: Mashhad outbreak was detected with a delay of about 2 to 7 days using EWMA algorithms as outbreak detection method while the utility of EWMA algorithms in real time detection of Bandar Abbas’ outbreak were on time good optimal. Maximum correlation value for EWMA 2 in relation to Mashhad outbreak was 0.60 at lag 2.
Conclusion: Applying the EWMA algorithm as an outbreak detection method at local levels is not suggested. However the characteristics of data are determinant of the performance of such detection methods.
M Karami, F Khosravi Shadmani , F Najafi,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: Knowledge of the magnitude of attributable burden of cardiovascular diseases (CVDs) due to diabetes is necessary for health policy, priority setting and preventing CVD deaths. Our study aimed at estimating the attribute of proportion of diabetes to the burden of cardiovascular diseases in Kermanshah, West of Iran.
Methods: World Health Organization Comparative Risk Assessment methodology was used to calculating Potential Impact Fraction (PIF). Data on the Prevalence of newly diagnosed diabetes mellitus (People who have fasting plasma glucose (FPG) equal or greater than 126 mg/dl) were obtained from 3rd Iranian surveillance of risk factors of non- communicable diseases and data on corresponding measures of effect were derived from a national- specific study with age and multivariate adjusted hazard ratios.
Results: Based on multivariate- adjusted hazard ratios, by reducing the percent of women with diabetes from 8.1 percent to the zero level and the feasible minimum risk level i.e. 4 percent, 11.2% and 5.7% of attributable Disability Adjusted Life Years (DALYs) to CVD are avoidable, respectively. The corresponding value for men at the theoretical (zero level) and feasible minimum risk level (3 percent) were 5.6% and 2.9%, respectively.
Conclusion: To better planning, decision making and priority setting, PIF should be applied to updated and revised burden of CVDs in Iranian Health system.
Gr Kheirabadi, Sj Hashemi, S Akbaripour, M Salehi, Mr Maracy,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: The rate of suicide varies amongst different parts of Iran. Since there is little knowledge about the risk factors for suicide attempts we carried out this study to determine the status of psychiatric disorders and risk factors of repeated attempted suicide in suicide attempters whom admitted to poisoning emergency in Isfahan, Iran.
Methods: Patients with having attempt to suicide, admitted to emergency ward in Khorshid Hospital in Isfahan and were interviewed by a trained psychiatrist during 2009 year. Interview was based on DSM-IV.
Results: Participants consisted of 703 individuals (424 of them were female) with mean age of 25.9±9.7. One hundred twenty five (125) had positive family history of suicide attempt, 501 people were first time suicide attempters, 106 second, 58 third, and the others were forth time or more suicide attempters. Bipolar spectrum disorders, unipolar depression and adjustment disorders were the more frequents psychiatric disorders respectively. Age, family history of suicide, kind of diagnosed psychiatric disorder and method of attempted suicide were meaningfully related to mean of attempt suicide frequency.
Conclusion: Bipolar spectrum disorders, especially recurrent depressive episodes is the major risk of repeated suicide attempt and co-morbidity of another psychiatric disorders increase highly the risk of suicide reattempt.
A Nassi, M Mehrabizade Honarmand, M Shehni Yailagh, S Bassaknejad, A Talebpour,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: One of the most common anxiety disorders in children is separation anxiety disorder (SAD). The purpose of the present study was to investigate the epidemiology of separation anxiety disorder in Isfahan primary school male student.
Methods: The present study was a descriptive study. The statistical population was all the male students from 7 to 9 years old, studying in second and third grades in primary schools of Isfahan. The sample of study consisted of 1514 male student, who were selected randomly by multi-stage sampling method. The instruments of this study consisted of the Separation Anxiety Disorder Scale, Spence Children's Anxiety Scale and Clinical Interview.
Data obtained were analyzed by using descriptive statistics and chi-square and logistic regression.
Results: The findings showed that the rate of separation anxiety disorder in male (7 to 9 year- old student) was %6/93. SAD were more common in 7 years old (7.4%). Children having record of hospitalization, immigration, single-parent households and close relatives of mortality had a higher rate of separation anxiety disorder.
Conclusion: This study shows that separation anxiety disorder among primary school male students is significantly high. Therefore it is important to consider the potential utility of early anxiety prevention/intervention programs, especially for children at this age group.
N Khanjani , L Ranadeh Kalankesh , F Mansouri ,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: The effects of air pollutants on respiratory mortality and morbidity are among the major concerns today. Few studies have been published on the association between mortality and air pollution in Iran.
Methods: This study was undertaken in Kerman, Iran. Mortality data was inquired from the Kerman City Health Authority (from March 2006 till Sept 2010) and air pollution data was requested from the Kerman Province Environmental Protection Agency (EPA). The Kerman Province EPA collects daily data on 7 air pollutants which are SO2, NO2, NO, NOx, PM10, CO and O3 by its urban measurement station.
Results: The relation between respiratory disease mortality and air pollution was determined by negative binomial regression. The daily mean of PM10 in Kerman was above 150 μgr/m³(unhealthy) on some days of the year. The results showed a significant relationship between increased male respiratory mortality and increase in ambient dust (p=0.03), O3 (p=0.004) and SO2 (p=0.03), but did not show a significant increase in female mortality death for any pollutant.
Conclusion: As there seems to be a significant relationship between increased ambient dust, O3, SO2 and respiratory mortality, susceptible people and those with background respiratory diseases should practice caution in case of increases in these air pollutants.
Hr Koohestani , N Baghcheghi ,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: Despite the extensive interest shown in depression occurring in stroke patients, little attention has been paid focus on depression of caregivers of stroke survivors particularly in Iran therefore this study was designed to assess the prevalence of depressive symptoms among caregivers of stroke survivors and to determine putative risk factors.
Methods: This cross-sectional analytic study was carried out among 140 caregiver's stroke patients were admitted in Valiasr Hospital affiliated to Arak University of Medical Sciences. The caregivers were interviewed before discharge, at 1 month and 3 months after that. Depression was evaluated with the Beck Depression Inventory. The ability of the person with a stroke to perform their activities of daily living was measured using the Modified Barthel Index (MBI).
Results: Most of the caregivers were the spouse of the patient (70.71% n= 95). The mean age of them was 57.1 (SD=11.2) years old. A total of 33.57% to 42.16% of all caregivers were depressed during the follow-up. During the follow-up, caregivers’ scores for depression statistically significant were increased. Caregiver depression was associated with stroke modified barthel index score and age of the patient.
Conclusion: The depressive symptoms of caregivers seem to have high rate. This suggests that assessment of caregivers' social, and emotional needs should be included as part of the general rehabilitation plan of the stroke patient.
Gh Yadegarfar, T Alinia, R Hassannezhad, M Fayaz, R Hosseini, J Sanati, J Harandi, V Haj Noroozali, Mr Baghi, E Mirzavand,
Volume 8, Issue 3 (12-2012)
Abstract
Background & Objectives: To be able to measure the extent of job stress, it is essential to use a standardized tool based on a standard theoretical model. The study aims to test the psychometric properties and criterion validity of the Farsi version of the Effort Reward Imbalance (F-ERI) questionnaire.
Methods: The Farsi version of the ERI Questionnaire was distributed to 227 male employees in Isfahan Polyacryle Company. Internal consistency, reliability, discriminative validity, and factorial structure were evaluated.
The relationship between scales and depression was measured assessed by using logistic regression to criterion validity. Data were analysed by SPSS 18 and LIZREL 8.5.
Results: Mean score of effort, reward, and overcommitment were 10.7, 41.4, and 14.2 respectively Cronbach’s alpha coefficients were 0.61, 0.85 and 0.67 and split-half coefficients were 0.53, 0.85, and 0.65. All of item-total correlations were more than 0.20 correlation between each item and its scale were more than 0.4 except for one item. Effort and overcommitement had a good fit for construct validity.
Conclusion: Current study results indicated the Farsiversion of the Effort Reward Imbalance (F-ERI) questionnaire is a reliable and valid tool to measure psychosocial stress at work among Farsi-speaking employees. It is advisable to evaluate the tool in longitudinal studies and other industries which included female employees. We refer the investigators to see the longitudinal results of current project which is under publication.
M Gholami Fesharaki , A Kazemnejad, F Zayeri, J Sanati, H Akbari,
Volume 8, Issue 4 (3-2013)
Abstract
Background and Objectives: Since there is inconsistency reports in relationship between shift work (SW) and blood pressure (BP), therefore we aimed to show any association between SW and BP by using of Bayesian Multilevel Modeling, which is a reliable method for this type of analysis.
Methods: The profiles of 4145 workers in Polydactyl Iran Corporation were examined in historical cohort between 1996 until 2008. All relevant analysis was performed by Win Bugs software.
Results: Approximately 98 percent of study population was male. Of total 1886 (45.5%), 307(7.4%), 1952 (47.1%) of participation were day worker, two rotation shift worker and three rotation shift worker respectively. After controlling confounding factors, there was no significant relationship with Systolic BP (P=0.911) and Diastolic BP (P=0.278).
Conclusion: In general, the results of our historical cohort study do not support a relationship between SW and BP. We suggest multi center and prospective cohort studies with controlling more confounding factors in this area.
Kh Isazadehfar , L Eslami , M Entezariasl,
Volume 8, Issue 4 (3-2013)
Abstract
Background & Objectives: The scorpionism is one of the important public health problem in several parts of the world
becauseeither incidence or severity of envenomations is high and managed with difficulty by health services. The
aim of this study was to describe the epidemiological and demographic information among humans stung by
scorpion in Ramhormoz, Iran.
Methods: In this analytic-descriptive study relevant information were gathered from Imam Khomeini hospital in
Ramhormoz, from April 2007 to April 2008.
Results: There were 3799 scorpion victims, 56% were from rural areas. Approximately 20 percent of the sting
cases occurred in the month of July (the height temperature in this region). Near 50 percent of victims were
between 11-30 years. Most of the stings were seen in exposed extremities (78.4%) mainly in the lower limbs
(40.5%). Stings mainly occurred at night between 6 p.m. and 6 a.m (44.3%). The scorpions’ spices were, 53.9%
yellow, 12.5% black and 34.6% unknown colors, respectively. The median time from sting to admission to the
emergency room (patient delay) was 1.5 hour.
Conclusion: It is suggested that informing people with educational campaign about the importance of receiving
prompt attention following a scorpion sting has potential value in reducing complications in the emergency room.
We would advise that public awareness and physician readiness combined with the availability of effective
antivenom significantly reduced lethality in this region.
F Khosravi Shadmani , H Soori, M Karmi, F Zayeri, Mr Mehmandar,
Volume 8, Issue 4 (3-2013)
Abstract
Background & Objectives: In the chain of vehicles, human and environment, the human factors are the most complex element in the causes of road traffic injuries (RTIs). Unauthorized speeding and overtaking are considered as the main human factors resulting RTIs. This study estimated the population attributablefraction of two human factors, the most common risk factors of rural roads, of RTIs.
Methods: To calculate the population attributable risk, the prevalence of unauthorized speeding and overtaking registered in Police data was employed. Effect size related to odds ratio was employed using Logistic regression. Joint effect of related risk factors also calculated and reported. Dasta were taken from national traffic police using the KAM 114 froms.
Results: The percentage of population attributable risk of unauthorized speeding for deaths at crash scene was 20.9 and for injured cases was 16.6. These values were 13.5 and 13.4 for unauthorized overtaking respectively. Corresponding for joint effects the population attributable risk was 31.6 for deaths and 27.8 for injuries.
Conclusion: The results illustrate the importance of speed control and unauthorized overtaking as a priority of RTIs in Iran. It is recommended that related laws and legislations should be pursued more seriously, and followed by more effectively.
E Masoudnia,
Volume 8, Issue 4 (3-2013)
Abstract
Background & Objectives: The etiology of adolescent’s depression is very complex one of variables that has been paid more attention in recent years is using modern communication technology particularly internet. The aim of this study was to determine the relationship between problematic cyberspace use and adolescent's depression disorder in Yazd city.
Methods: A total of 535 (218 male and 317 female) high school students were recruited. Internet Addiction Test (IAT) and Child Depression Inventory (CDI) were used to evaluate the presence and severity of problematic internet use and also depression.
Results: Approximately twenty-two percent adolescents (21.7%) met the criteria for problematic cyberspace use. The presence of problematic cyberspace use was significantly associated withdepression, generally
(P < 0.01) and its components: Sadness/Somatic Worries (P < 0.01) Negative Self-Image/ pessimism
(P < 0.01) self-blame (P < 0.01) lethargy (P < 0.01) and isolation (P < 0.01). Hierarchical multiple linear regression analysis showed that problematic cyber use, explained for 23.7% of the variance of depression.
Conclusion: Problematic cyber use is a powerful risk factor for adolescent's mood health and increase the risk of depression disorder among adolescents. Therefore, in order to prevention of negative effects of problematic cyber use on adolescents mood health, behavioral and cognitive interventions to change cyberspace use pattern is seems necessary.
Ar Bahonar, K Amiri, Hd Akbarin, N Rasoli Beirami, Hr Amiri, F Imani Tabar, Sh Khajeh Nasiri , S Arab Zadeh, V Iranian Veterinary Organization, As Makenali,
Volume 8, Issue 4 (3-2013)
Abstract
Background & Objectives: Prevention and control of brucellosis in animals is the main route of its prevention in human. After detecting a brucellosis outbreak in an industrial dairy cattle farm in Isfahan province in Iran, an epidemiological investigation was carried out to determine prevalence of seropositive cows and incidence rate inorder to eliminate positive couws.
Methods: This study was carried out to determine abortion rates in caws. RBPT, SAT and 2ME serologic tests were used for detecting infected cows and Brucella agar for isolation of bacteria. Data analysis was performed by Chi-square test and calculation of cumulative incidence ratio.
Results: Of total 1395 female cows above 4 months age, 706 infected animals were found during investigation (March-December 2011). Incidence of abortion in infected cows was significantly higher than no infected
(34% versus 14%, P<0.05). Culture for 47 milk samples was positive for brucella out of 100 milk samples.
Conclusion: Attention to using reduce dose of RB51 vaccine, controlling of import animal in farm besides biosecurity are the main factors for prevention of similar outbreaks in dairy farms.
E Pourbakhtyaran, Mh Sowlat, A Rashidian, P Pasalar, N Rastkari, M Yunesian,
Volume 8, Issue 4 (3-2013)
Abstract
Background & Objectives: In the last decade, there have been some claims about hazards of Sodium bicarbonate in bread, in public and scientific sites. Currently, the use of sodium bicarbonate in bread processing is forbidden in Iran. Therefore, the present study sought to assess the current evidence on the adverse effects of sodium bicarbonate use from oral route on public health.
Methods: Different databases, including Scopus, Pubmed, and Ovid were searched for hazards of sodium bicarbonate in baking.
Results: Based on this systematic review, there was no study showing any adverse effects of Sodium bicarbonate when used in producing bread. However, we found many studies about the use and medical application of it. The reported adverse effects mostly included gastrointestinal and electrolytes implications at medical doses which are significantly higher than those used in bakery, or some complications due to accidental or excessive oral ingestion of sodium bicarbonate.
Conclusion: Not only was there no evidence on the adverse effects of sodium bicarbonate on public health, but at medical doses, many useful effects were also reported in clinical trial studies. Therefore, it is assumed that the use of Sodium bicarbonate at normal doses does not have any adverse effects on human and can be used for bakery in Iran.
