Showing 46 results for Cancer
Ma Soleimani, N Dalvand, S Zarabadi Pour , Z Alimoradi, A Görgülü, N Bahrami,
Volume 17, Issue 1 (5-2021)
Abstract
Background and Objectives: Accurate assessment of patients' death depression requires a specific tool that is appropriate to the culture of each community. Therefore, the aim of this study was to evaluate the psychometric properties of the Death Depression Scale in women with breast cancer.
Methods: In this methodological study, 246 breast cancer patients presenting to Qazvin Provincial Hospital completed the 17-item Templar Death Depression Scale. Psychometric properties of this scale were evaluated by exploratory and confirmatory factor analysis. Reliability was also assessed using Cronbach's alpha, omega and composite reliability.
Results: Exploratory factor analysis showed that six items in the Persian version did not acquire the required loading factor, and were omitted. The remaining eleven items as a single factor accounted for 66.91% of the variance of this concept. In confirmatory factor analysis, 11 items had appropriate fit indices (χ2 = 97.664, p <.001, χ2 / df = 2.504, GFI = .932, CFI = .972, IFI = .973, TLI = .961, SRMR = .030, and RMSEA = .079). A Cronbach's alpha coefficient of 0.95, Omega coefficient of 0.95, and composite reliability coefficient of 0.96 indicated the acceptable reliability of the 11-item version.
Conclusion: The results of this study showed that the 11-item Death Depression Scale was valid and reliable in Iranian patients with breast cancer. Given the appropriate psychometric parameters, this scale can be used to assess death depression in future studies.
Malihe Safari, Salman Khazaei, , Mohammad Abbasi, Ghodratollah Roshanaei,
Volume 17, Issue 2 (9-2021)
Abstract
Background and Objectives: The incidence of rectal cancer is increasing in developing societies, especially in younger age groups. The aim of this study was to evaluate the factors affecting the survival of patients with rectal cancer in the presence of competing risks.
Methods: In this retrospective cohort study, the data of 121 patients with rectal cancer during 2001-2017 were studied. Death related to cancer progression was considered as the interest outcome and other causes of death were considered as competing risks. Cause-specific and sub-distribution hazard models were used to investigate the factors affecting patient survival in the presence of competing risk.
Results: The mean (SD) age of the patients was 53.4 (13.9) years and 68 patients (56.2%) were male. The results of log-rank test showed that sex, age, metastasis, type of first treatment, rate of penetration into intestinal wall, tumor location, number of lymphomas involved and tumor size had significant effects on the patient survival (P<0.05). Based on cause-specific and sub-distribution hazard models, tumor stage, lymph node metastasis, and tumor grade had significant effects on death hazard due to the cancer progression (P<0.05).
Conclusion: Due to the need to consider competing risks, the results of both competing risk methods showed that tumor grade, lymph node metastasis and stage increased the instantaneous hazard and hazard of cancer death. Therefore, to determine the specific risk factors for each cause of death in the survival analysis, competing risk methods should be used if there is more than one cause of death.
A Naghi Pour, A Moghimbeigi, N Shirmohamadi, A Soltanian, S Khazaei, Sh Nick Ceiar,
Volume 17, Issue 4 (3-2022)
Abstract
Background and Objectives: Breast cancer has the highest incidence in the Iranian women.
Methods: A cross-sectional study was conducted. All female with breast cancer during 2008-2015 were enrolled. Breast cancer registration is based on the pathology method in Iran. The information about female with breast cancer was collected from their files in the cancer registry department of Hamadan Health Center. The samples were divided into four groups according to age (<50 and> 50) and location (city, village). GeoBUGS was used to generate a map of high-risk areas in Hamedan Province based on the adjusted relative risk estimate (RR*) in OpenBUGS v 3.2.3 software.
Results: This study included 1316 females with breast cancer. The mean age of the patients was 50.38±12.98 years. The results of the study showed that high-risk areas of breast cancer for were Assadabad urban females aged over 50 years (RR*(i)=1.32, CI= 0.99,1.79) and Tuyserkan (RR*(i)=1.09, CI= 1.08,1.38) and Razan (RR*(i)=1.09, CI= 0.85,1.40) for females below 50 years. In addition, Razan for rural females over 50 years old (RR*(i)=1.18, CI=0.82,1.73) and Malayer for females below 50 years old (RR*(i)=1.08, CI= 0.81,1.45) were high risk areas for breast cancer in Hamadan Province.
Conclusion: The distribution of breast cancer is different at different ages and in the cities of Hamadan Province. Asadabad, Tuyserkan, Razan and Malayer were high risk areas for breast cancer in Hamadan Province.
N Zanjari, M Sasanipour,
Volume 18, Issue 1 (5-2022)
Abstract
Background and Objectives: The rate of the increase in life expectancy has slowed down during the last two or three decades in Iran. In this study, we examined the role of change in thecause of death older adults in increasing life expectancy in Iran between 2006 and 2016.
Methods: Death data by age, sex, and cause in Iran between 2006 and 2016 were obtained from the death registration and classification system of the Ministry of Health and Medical Education. Using the Brass-Trussell and generalized Benett-Horiuchi method, underreporting of child and adult death registration was corrected. Then, using the Arriaga decomposition method, the role of age groups and causes of death of Iranian older adults in increasing life expectancy at birth was calculated.
Results: Men’s life expectancy at birth increased by 3.7 years during 2006 to 2016, and the contribution of older adult’s death changes on this increase was estimated at 2 years. Out of the total increase of 3.1 years in women’s life expectancy, 1.57 years was related to changes in the older adults’ cause of death. Furthermore, 74% and 57% of the role of change in the cause of death among older men and women in increasing the life expectancy was related to cardiovascular diseases.
Conclusion: Considering the transition of age structure in the coming decades, transition of death trend to older ages is expected to continue. The results of this study showed that it is necessary to pay more attention to diseases that affect older people in policy priorities.
Zahra Jafarabadi, Farid Abolhasani, Mohammad Hassan Lotfi, Hossein Fallahzadeh,
Volume 18, Issue 2 (9-2022)
Abstract
Background and Objectives: Colorectal cancer is the second and fourth most common cancer in Iranian women and men, respectively. This cancer ranks fourth and fifth in men and women, respectively, among Yazd population. This study aimed to estimate the burden of colorectal cancer in Yazd province in 2016.
Methods: This descriptive cross-sectional study was performed on the population of Yazd province in 2016. CanMod software was used to calculate the burden of colorectal cancer. The required information included the population of Yazd province, the incidence of colorectal cancer, the death rate due to colorectal cancer, the death rate due to all causes and the survival rate of patients; The Cancer Registration System, the Provincial Death Registration System and the opinions of provincial experts were collected and included, respectively.
Results: The total burden of colorectal cancer in Yazd province was 632 years (382 years in men and 250 years in women); The YLL and YLD of colorectal cancer in both genders were 478 years and 154 years, respectively. The burden of colorectal cancer in men was 65 years and in women 45 years (per 100,000 population). The peak age of disease burden was estimated in the age group over 60.
Conclusion: Due to the high incidence and treatment in the early stages of the disease, screening and diagnosis in the early stages can be one of the health priorities of the province. However, the final judgment is made when the burden of other diseases and injuries is calculated in the province.
Mohammadreza Balooch Hasankhani, Aliakbar Haghdoost, Yunes Jahani,
Volume 19, Issue 2 (9-2023)
Abstract
Background and Objectives: Time trend analysis of factors such as disease and mortality rates is a crucial component of health planning for any community. It allows for a more accurate interpretation of changes over time. This study was conducted to examine the performance of the Joinpoint regression model in analyzing time trends.
Methods: This study aims to first provide a simplified understanding of the Joinpoint regression model and then demonstrate its application on data regarding the 30-year trends of liver cancer mortality due to alcohol consumption in Iran.
Results: The results of the time trend analysis indicate that the age-standardized mortality rate of liver cancer due to alcohol use consumption has decreased by an average of 0.8% per year over the 30-year period in Iran (1990 to 2019). The projections also suggest that this declining trend will continue.
Conclusion: In general, the main advantage of the Joinpoint regression model over other models is its ability to identify periods where significant changes in trends have occurred. Based on the results, the mortality rate of liver cancer due to alcohol use consumption over the 30-year period in Iran can be divided into five periods with different rates of change.
