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Showing 12 results for Blood

Mr Aflatoonian,
Volume 3, Issue 1 (9-2007)
Abstract

Background & Objectives: Drug abuse and addiction is one of the four major crises in the world. The first step in combating any disease or social problem is proper organization. The aim of this case-control study was comparing the distribution of blood groups between healthy blood donors and clients of drug rehabilitation clinics in the city of Bam.
 Methods: In this case-control study, cases were 249 drug users attending the city's rehabilitation clinic. Controls included 360 healthy blood donors at the headquarters of the Blood Transfusion Organization in Bam. We extracted and analyzed data on demographic characteristics, blood group and RH, using the software package SPSS.
Results: This study showed that the AB blood type is more common in drug addicts than in healthy blood donors.
Conclusions: Many studies have reported that an association between ABO blood groups/ RH and various health outcomes such as infections and non-infectious diseases as well as mental and social problems. Our study showed that there is a significant relationship between drug addiction, AB blood type, and negative RH. It therefore seems that genes play a role in the tendency towards addiction. This investigation may be valuable in the sense that it may prompt further research in fields such as genetic, immunology and other related disciplines.
A Nasermoaddeli, M Sekine, S Kagamimori,
Volume 4, Issue 2 (9-2008)
Abstract

Background & Objectives: A strong sense of coherence (SOC) has been associated with a reduced risk of all causes and cardiovascular mortality, but the underlying mechanism remains less clear. This study investigated the association of sense of coherence (SOC) with years-long blood pressure change, in male and female subjects.
 Methods: In 2001 a questionnaire survey and BP measurement were conducted among 1760 Japanese civil servants (963 men and 797 women) aged 20 to 60 years, who did not have hypertension. Thereafter which their Blood pressure was measured annually for 4 consecutive years, till the year 2005. The generalized estimating equation method was used to analyze the data.
Results: The systolic and diastolic blood pressure of men in SOC quartile 3 (SOC score: ≥53~<58) was estimated to rise 5.00 and 3.52 mmHg less in 4 years (p<0.05) than the lowest quartile (SOC score: ≤46).
Conclusions: Results suggested that the health promotion effects of SOC on annual BP change in men follows a curvilinear pattern. Among men individuals with moderately high SOC might have lower risk of developing high blood pressure.
J Porolajal, R Majdzadeh,
Volume 4, Issue 3 (3-2009)
Abstract

Background and Objectives: Hepatitis B virus (HBV) infection is a major public health problem worldwide. Islamic Republic of Iran is located in mesoendemic region (prevalence 2%-7%). The aim of this study was to assess prevalence of chronic HBV in Iran according to demographic characteristics.
Methods: Medline, Embase, Science Citation Index Expanded, Ovid, Google Scholar, IranMedex, SID, Magiran and The Scientific Journal of Iran Blood Transfusion Organization (SJIBT) from 2000 till May 2008 were searched. Cross-sectional studies concerning prevalence of hepatitis B infection in Iran were included irrespective of language and date. The outcome of interest was prevalence of chronic HBV infection detected by blood specimen positive for HBsAg.
Results: We icluded 34 studies. The prevalence of chronic HBV infection was estimated about 1.7% or lower in general population 0.8% (95% CI: 0.6%-0.9%) in blood donors and 3.2% (95% CI: 2.3% - 4.1%) in intravenous drug users. Prevalence of chronic HBV infection in beta thalassemic patients varied from zero to 1.5%. Prevalence of chronic HBV infection was higher in middle aged and elders than children, adolescent and youth and was 25% higher in males than females.
Conclusions: Since mass vaccination of hepatitis B in 1993, prevalence of chronic HBV infection has being reduced among children and adolescents. These age groups comprise a large proportion of general population and reduction of HBV infection in this age group may impact on total prevalence of hepatitis B infection, so that now Iran may be considered a hypoendemic region for HBV infection.
R Nosratabadi , E Saneimoghadam , M Arababadi, S Khosravi , Gh Hassanshahi , R Vazirinegad ,
Volume 5, Issue 2 (9-2009)
Abstract

Background and Objectives: Anaphylactic reaction is one of the most important transfusion anaphylactic reactions in medicine. During transfusion if Individuals with IgA deficiency take blood which containing IgA, they would suffer from severe allergic reaction. Since there is a little known about this in different ethnic groups in Iran we have decided to evaluate this issue in Sistan & Baluchestan province in Iran. Methods: During one year, blood samples were collected from 3837 volunteer blood donors. Then the serum samples were tested for IgA titer by nephlometry and SRID techniques.
Results: According to our results only, one donor (0.026%) was found to have IgA less than 5mg/dl and 34(0.9%) cases had IgA: 5-30 mg/dl while 3798(99%) had IgA more than 30mg/dl.
Conclusions: With regards to very low prevalence of IgA deficiency in blood donors in Southeast part of Iran, it seems that anaphylactic reactions most likely be due to other factors in the individuals that receive blood products.
N Esmailnasab, A Afkhamzadeh, A Ebrahimi ,
Volume 6, Issue 1 (6-2010)
Abstract

Background & Objectives: According on surveys in Iran more than two million persons have non insulin diabetes mellitus. There are evidences that good glycemic control reduces the risk of diabetic complications. This study was designed to evaluat the glycemic control by using fasting blood sugar and hemoglobin A1C estimation and their relation with some variables.
Methods: This cross sectional study carried out on 411 people with type 2 diabetes who referred to Tawhid diabetes center in Sanandaj. Demographic and other variables were gathered by a deigned questionnaire. Univariate analysis and multivariate analysis (logistic regression) were used. Results: In Univariate analysis FBS showed a significant relationship with education, job and referral style and HgA1c was statistically significant with sex, age, education, and job. But logistic regression showed other
Results: in final model FBS and HgA1c were associated with body mass index and referral style and HgA1c had association with only body mass index and referral style. Correlation confidence between FBS and glycated hemoglobin was (r = 0.54).
Conclusions: It is concluded that BMI and referral style have association with diabetes control.
M Akhavan Sepahi, Sh Hejazi, A Koopai, K Eshagh Hoseini, A Belbasi,
Volume 8, Issue 1 (7-2012)
Abstract

Background & Objectives:
Nowadays the performance of hospital blood banks is assessed by cross-match to transfused unit ratio which it is recommended to be less than 2.0. The aim of this study was to evaluate the most common indications for blood transfusion in Qum University hospitals.
Methods: In this retrospective study 4370 blood order forms from March 2010 till April 2011 were assessed. To calculate C/T ratio, the number of cross-matched units was divided by the number of transfused units.
Results: Of total 4370 blood order, 57.1% were male. From all blood order forms, 16.42% (C/T : 1.196) were not transfused. The highest rate of blood orders pertained to surgery emergency and trauma (23.3%), hematology and oncology (14%), gynecology (11.3%), internal ward and nephrology (8%), infectious ward (6.9%), burn ward (5.9%), general surgery (4.4%), orthopedics (3.2%), ICU (2.3%) and pediatrics (8.6%).         Packed cell was the product with the highest order rate of 78.7% in Qom teaching hospitals however, out of this rate 44% remained untransfused.
Conclusion: According to the findings of this study the rate of non-transfused ordered blood components in Qom teaching hospitals seems very high. Thus, it is recommended to employ the international and/or national guidelines in order to reach to optimal rate.

Normal

M Gholami Fesharaki , A Kazemnejad, F Zayeri, J Sanati, H Akbari,
Volume 8, Issue 4 (3-2013)
Abstract

Background and Objectives: Since there is inconsistency reports in relationship between shift work (SW) and blood pressure (BP), therefore we aimed to show any association between SW and BP by using of Bayesian Multilevel Modeling, which is a reliable method for this type of analysis.
 Methods: The profiles of 4145 workers in Polydactyl Iran Corporation were examined in historical cohort between 1996 until 2008. All relevant analysis was performed by Win Bugs software.
Results: Approximately 98 percent of study population was male. Of total 1886 (45.5%), 307(7.4%), 1952 (47.1%) of participation were day worker, two rotation shift worker and three rotation shift worker respectively. After controlling confounding factors, there was no significant relationship with Systolic BP (P=0.911) and Diastolic BP (P=0.278).
Conclusion: In general, the results of our historical cohort study do not support a relationship between SW and BP. We suggest multi center and prospective cohort studies with controlling more confounding factors in this area.
H Safabakhsh, F Tehranian, B Tehranian, H Hatami, G Karimi, M Shahabi,
Volume 9, Issue 1 (5-2013)
Abstract

Background & Objectives: Prevalence of cytomegalovirus (CMV) infection varies is highly prevalent in different societies. CMV infection in susceptible patients is associated with serious morbidity and a high mortality and is a matter of concern for blood bank professionals and blood transfusion recipients, especially in cases of transfusions to neonates and immunocompromised patients. Thus, the present study aimed to determine the prevalence rate of anti-CMV antibodies among the blood donors of Mashhad Blood Transfusion Center.
 Methods: This seroepidemiology study carried out on 1008 samples from blood donors in Mashhad Blood Transfusion Center and the prevalence rate of anti-CMV antibodies (IgM, IgG) was estimated by ELISA method in the samples
Results: Out Of 1008 serum samples from donors, 1000 persons (99.2%) had anti-CMV IgG and 16 donors (1.6%) had anti-CMV IgM in their sera. Eight (8) persons had no anti-CMV IgG and IgM in their sera.
Conclusion: The high rate of prevalence of CMV in this study region indicating blood component screening strategies for blood transfusions require particular attention among healthcare professionals as part of the actions for prevention and reduction of primary infections caused by CMV.
A Biderafsh, M Karami, J Faradmal, J Poorolajal, N Esmailnasab,
Volume 10, Issue 3 (12-2014)
Abstract

  Background & Objectives : Considering the high prevalence of hypertension and its increasing trend in Iran as the most important known modifiable risk factor of stroke, this study was performed to determine the pattern of hypertension and the related population attributable fraction (PAF) of stroke in Hamadan Province.

  Methods: Blood pressure data of over-19-year-old population of Hamadan Province from 2005 to 2009 was extracted from the non-communicable diseases risk factors surveillance system . The point prevalence and 95% confidence interval (95% CI) of hypertension was reported in the study population according to sex and age groups. The trend of hypertension was depicted using a line plot. To calculate PAF, the data of the prevalence of hypertension in 2009 was used. Corresponding hazard ratio was obtained from the available literature.

  Results : The prevalence of hypertension was 9.4 (8.2 – 10.6) in 2005, 7.5 (5.9 – 9.3) in 2006, 14.2
(12.1 – 16.5) in 2007, 13.8 (11.7 – 16.1) in 2008, and 12.2 (10.3- 14.5) in 2009. The mean and standard deviation of systolic blood pressure was 120.88 (19.73) and 124.19 (19.24) in the participants in 2005 and 2009, respectively. The study results showed that 19.84% of the strokes in Hamadan Province were due to hypertension .

  Conclusion: The results of this study confirmed the considerable contribution of hypertension to stroke in Hamadan Province. Accordingly, policy makers are strongly recommended to consider controlling and preventive strategies for hypertension as a priority .


S Akbarpour, Y Jahangiri-Noudeh, M Lotfaliany , N Zafari, D Khalili, M Tohidi, Ma Mansournia, F Azizi, F Hadaegh,
Volume 11, Issue 2 (9-2015)
Abstract

Background & Objectives: Considering the importance of CVD risk factors in diabetic and non-diabetic populations and the high prevalence of diabetes and cardiovascular risk factors, we studied the trend of anthropometric indexes, blood pressure, smoking and lipids in diabetic and non-diabetic populations.

Methods: The data of Tehran Lipid and Glucose Study was used in this investigation. The study population comprised 1045 diabetic and 5136 non-diabetic subjects. To investigate the secular longitudinal trends, the Generalized Estimation Equation method was employed. All statistical models were adjusted for age to eliminate the potential confounding effect of age. The interaction between the diabetes status and each phase of the study was checked in a separate model in GEE.

Results: Over a decade, the serum levels of TC, TGs, LDL-C and non HDL-C decreased although about 60% of the diabetic population did not reach the therapeutic goals of non-HDL-C and LDL-C levels until 2011. Control of hypertension was more successful in females, but about 60% of both males and females with diabetes were still hypertensive at the end of follow-up period. Smoking increased during the follow-up.

Conclusion: This study showed that among CVD risk factors, healthcare professionals paid more attention to hypercholesterolemia neglecting other risk factors including hypertension and central obesity.


Y Madmoli, Sm Akhaghi Dezfuli, R Beiranvand, B Saberi Pour, M Azami, M Madmoli,
Volume 13, Issue 2 (9-2017)
Abstract

Background and Objectives: Regular blood transfusions in patients with hereditary hemolytic anemia, especially thalassemia, increase the survival of most patients but also may result in infection with viruses like hepatitis. In order to identify these diseases and other complications in people with thalassemia, this study aimed to investigate epidemiological and clinical findings in patients with thalassemia in Dezful in 2015.
Methods: In this descriptive-analytic study, data were collected from medical records in Dezful thalassemia Clinic by the census method. The collected data included gender, age, location, ethnicity, blood type, transfused blood type, time between blood transfusions, medications, vaccinations, underlying diseases, and operations and their time.
Results: The records of 174 thalassemia patients with a mean age of 23.60 years were evaluated. Of these, 23 patients (13.2%) had thalassemia intermediate and 151 (86.8%) had thalassemia major. The last mean serum ferritin was 2760.60. Independent T test showed a significant relationship between the type of thalassemia and age at diagnosis (P=0.000). There was a significant positive correlation between age and blood transfusion intervals so that the intervals increased with age (P=0.004) (r=0.21).
Conclusion: The high mean age in the center compared to other studies as well as the low frequency of side effects indicate the effectiveness of new treatments and increased survival of these patients.
Tahereh Tiemori, Marjan Ajami, Sareh Shakerian, Morteza Abdollahi,
Volume 20, Issue 2 (9-2024)
Abstract

Background and Objectives: Evidence shows that blood lipid disorders in people are influenced by their unhealthy diet. This study was conducted with the aim of investigating the dietary pattern of people with lipid disorders and the status of non-communicable diseases in the studied population.
Methods: A cross-sectional study was conducted on 300 patients with lipid disorders. The participants were selected among people with lipids who referred to comprehensive health service centers in Alvand city by multistage sampling method. The data were collected using a semi-quantitative food frequency questionnaire (FFQ). The findings were analyzed by SPSS software.
Results: Three dietary patterns including healthy, unhealthy and average were identified in the research participants. Most people (66.3%) followed a moderate dietary pattern. Also, 85% of people were overweight or obese. The results of the logistic regression analysis showed that an unhealthy eating pattern increases the likelihood of developing diseases by 2.267 times compared to a healthy eating pattern. It also showed that with increasing age, the probability of contracting the disease increases by 1.093. Also, there was a significant relationship between food pattern and education level (P<0.05). In this study, there was no significant relationship between age, marital status of people and their food pattern (P>0.05).
Conclusion: The results showed that people who follow an unhealthy food pattern have more non-communicable diseases. Therefore, it seems that modifying the food pattern through nutrition education is appropriate and can be effective in preventing other non-communicable diseases in the future.


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