Iranian Journal of

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Background & Objectives: Triglyceride/HDL-cholesterol ratio (TG/HDL-C) has been shown as an indicator for metabolic syndrome (MetS). This study aimed to detect the role of this ratio to predict coronary heart disease (CHD) outcome in an Iranian men population with high prevalence of MetS.
Methods: 1824 men ≥ 40 years old, free of clinical cardiovascular disease at baseline, were included in the study from February 1999 to August 2001. Serum level of total cholesterol (TC), HDL-C, TG, and risk factors of CHD including age, systolic blood pressure, diastolic blood pressure, body mass index, diabetes, smoking and family history of cardiovascular diseases were measured at initial phase of study.
Results: During a median follow up of 6.5 years until March 2007, a total of 163 new CHD events occurred. According to a Cox proportional hazard modeling, after adjustment for TC and other risk factors, men in the top quartile of TG/HDL-C relative to first quartile had a significant hazard ratio (HR) of 1.85 (95% CI, 1.07-3.17). Combined HR for TC and TG/HDL-C (men in the top quartiles of both TC and TG/HDL-C relative to first quartiles) after adjustment for other risk factors was 6.13 (95% CI, 2.37-15.86).
Conclusions: The evaluation of both TG/HDL-C ratio and TC should be considered for CHD risk prediction in Iranian male population.

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  Background and Objectives : Previous studies have reported contradictory results regarding the association of Shift Work (SW) and Blood Cholesterol (BC). In this paper, we studied the relationship between SW and BC.

  Methods: The data of this historical cohort study was extracted from annual observations of the workers of Esfahan’s Mobarakeh Steel Company selected through cluster random sampling between 1996 and 2011. In this research, we assessed the effect of SW on BC with controlling BMI, age, work experience, marital status, smoking, and educational status.

  Results : Five hundered and seventy four male workers participated in this study with a mean (SD) age of 41.89 (7.51) and mean (SD) work experience of 16.75 (7.16) years. In this study, after controlling confounding factors, we found no significant relationship between SW and BC.

  Conclusion: Because our study showed no relationship between SW and BC, we can state that this relationship does not exist with more certainty.