Background and Objectives: Antibiotic residues in food, including eggs, are potentially risky to public health. The objective of this systematic review was to evaluate the relative frequency of antibiotic residues in eggs sold in Iran.
Methods: PubMed, Scopus, Web of Science, Google Scholar, MagIran, Scientific Information Database, and IranDoc were searched. Two independent reviewers screened the titles and abstracts based on the inclusion and exclusion criteria. The inclusion criteria were articles written in English or Persian investigating the relative frequency of antibiotic residues in eggs in Iran, and the exclusion criteria were articles without an available full text. Frequency data, publication year, diagnostic test type, and sampling location were extracted from relevant articles.
Results: Among the 217 identified results, 11 articles were included in the systematic review. ELISA (six articles) was the most frequently used diagnostic test. East Azerbaijan province accounted for the most significant number of studies (four articles) based on the geographical distribution of sampling locations. Seven classes of antibiotics and 12 types of antibiotics were estimated in terms of antibiotic residues, with tetracyclines (5 articles, 6 assessments) having the highest number of assessments. In addition, the highest reported relative frequencies were related to tetracycline residues (100%) in Isfahan and chloramphenicol (75%) in Tabriz.
Conclusion: Tetracycline and chloramphenicol residues had the most significant relative frequency in eggs across Iran.
