Showing 5 results for Gastroenteritis
H Hatami, B Kalantari, Ar Farsar, A Asgari, S Karkhaneh,
Volume 11, Issue 4 (3-2016)
Abstract
Background and Objectives: Acute gastroenteritis is mainly caused by some viruses and often NoVs. In January 2014, an outbreak of gastroenteritis occurred in Pardis City, in Tehran and that made 5064 patients visit health centers. The purpose of this study was to investigate the epidemiology of the disease in this region.
Methods: This cross sectional study was done to evaluate the outbreak of gastroenteritis in Pardis City in January 2014. In this outbreak, the data of 1150 out of 5064 patient was collected by health centers. The inclusion criterion was residing in the location for at least ten days before its occurrence. The exclusion criterion was incomplete recorded data. A number of 126 human samples underwent laboratory investigation. The data collection tool was was line listings and data analysis was done with Excel 2010 and SPSS21 software.
Results: female and male patients comprised 57.8 and 42.2% of the study population and 59.7% of the subjects were under 27 years of age. The most prominent symptoms were vomiting (94.9%), diarrhea (37.7%), abdominal pain (18.8%), and fever (0.6%). The results showed that bacterial contamination, parasites, serologic tests for hepatitis E (IgM-HEV) and hepatitis A (IgM-HAV) and RT-PCR for hepatitis E and A were negative but 6 out of 9 fecal samples were positive for NoVs using molecular RT-PCR.
Conclusion: The results revealed the role of NoVs in Pardis City in 2014. Moreover, clinical and epidemiological characteristics of the population, season, and the environment of this diagnosis were confirmed.
S Holakouie Naieni , Sh Holakouie Naieni , K Holakouie Naieni ,
Volume 13, Issue 4 (3-2018)
Abstract
Background and Objectives: Food-borne diseases are serious problems in public health. Since the outbreaks can be prevented, we need to take action in the prevention of such infection. On 28 June, 2014 cases of gastroenteritis occurred in students living in dormitories of a medical university; therefore, this study aimed to investigate the outbreak of gastroenteritis to determine its risk factors.
Methods: This case - control study was performed to evaluate students. A total of 70 patients with gastroenteritis in the outbreak of 16 June 2014 were selected. A total of 70 students without any gastrointestinal complaints in the weeks before the outbreak were also selected as the control group using convenient sampling.
Results: The results of this study provided 4 main themes (challenges of access to the data of the surveillance system, challenges of access to the data of national surveys and ordered projects, challenges of access to the data of electronic health records, and challenges of access to confidential data) and 15 sub-themes.
Conclusion: According to the results, having lunch prepared by the university on 16 June was the likely cause of the outbreak on 17 June in student living in dormitories. Hygiene in cooking and food storage, especially in public places such as schools and universities are important in the prevention of food-borne outbreaks.
M Karami, A Doosty Irani, Sj Battaei, L Rafati, M Javaheri, M Kheir Andish , M Farhadi, M Hashemi, K Mozafari, A Akhlagh, M Shojaeian, Ar Maleki, R Rostam Abadi , Sh Torkshavand, M Khodabakhshi,
Volume 16, Issue 3 (11-2020)
Abstract
Background and Objectives: Water and foodborne diseases are major causes of mortality worldwide. The aim of this study was to investigate the factors affecting an gastroenteritis outbreak in Hamadan county in summer of 2019.
Methods: This study was performed based on the outbreak investigation process. After producing hypotheses based on preliminary field studies, a case-control study was conducted on 45 cases and 45 controls to investigate the factors associated with the outbreak. New cases of the disease were included according to the case definition. A logistic regression model was used to investigate potential risk factors.
Results: A total of 171 people were affected in this outbreak from 25 June 2019 to 01 July 2019. The at-risk population in this outbreak was 3410 individuals. The attack rate was 5.1%. Abdominal pain, vomiting, and nausea were the most common symptoms with a prevalence of 77.8%, 73.3% and 68.9%, respectively. The results of the case-control study showed that the consumption of tap and spring/well water increased the odds of disease by 4.63 and 4.13 times compared to boiled water, although these relationships were not statistically significant. The odds of diseases were significantly lower in people aged 30-45 years and 46-85 years compared people aged 15 years old and younger.
Conclusion: Based on the results of this study, the outbreak was related to contaminated water consumption. Therefore, regular monitoring of drinking water status is very important for the local health system.
H Amiri, Sh Salmanzadeh, F Safdari, A Shirali, E Azhdarinia, Kh Sarmadi, Sa Alavi, H Salehi, M Eskandari,
Volume 16, Issue 4 (3-2021)
Abstract
Background and Objectives: In June 2018 , 537 residents of a rural area in Khuzestan Province presented to the regional Comprehensive Health Service Center for gastroenteritis symptoms. This study was designed to determine the extent and cause of the outbreak.
Methods: A case-control study was performed after random selection of the case and control groups (80 cases and 88 controls). Clinical and water samples were analyzed for parasitic, bacterial and viral pathogens in local, provincial and national laboratories. Odds ratios with corresponding 95% confidence intervals were used to assess the relationship between disease and exposure.
Results: The odds ratio of rural plumbing water consumption as a risk factor was 3.3 (95% CI: 1.7-6.2). Using in vitro methods, Shigella sonnei was isolated in clinical samples and enterohemorrhagic Escherichia coli and enteropathogenic Escherichia coli were isolated from both clinical samples and water samples taken from the intake basin of water supply facilities.
Conclusion: Consumption of rural plumbing water Since 26 June 2018 as well as the water stored in domestic tanks at certain water-shut-off times is associated with gastroenteritis outbreak. To prevent similar outbreaks, continuous chlorination of drinking water during distribution through rural pipelines should be done. To prevent secondary outbreaks after the epidemic phase, educating and informing people about personal hygiene is essential.
Tina Fallah, Ameneh Elikaei, Roxana Mansour Ghanaie, Abdollah Karimi, Iraj Sedighi, Marjan Tariverdi, Arezu Amirali, Tayebe Nazari, Negin Nahanmoghadam, Alireza Nateghian, Seyed Hamidreza Monavari, Seyed Mohsen Zahraei, Sussan Mahmoudi, Masoud Alebouyeh,
Volume 19, Issue 1 (6-2023)
Abstract
Background and Objectives: Identification of rotavirus genotypes in children is clinically important. This study aimed to determine the spectrum of rotavirus genotypes and assess their correlation with demographic variables and clinical manifestations in hospitalized children.
Methods: To determine rotavirus genotypes, rotavirus positive stool samples of symptomatic children were included in the study between December 2019 and March 2020. RNA extraction and cDNA synthesis for VP7 and VP4 genes were performed following standard protocols. Genotypes were determined using specific primers. Validation of results was done through sequencing and bioinformatic analysis. Data were statistically analyzed using SPSS version 20 and GraphPad version 9.5.0.
Results: Among the infected patients, three genotypes emerged as dominant in the studied population. The study demonstrated a significant correlation between genotype frequency and seasonal variations (p-value=0.0077), as well as between genotypes, hospitalization, and severity of diarrhea. While significantly more types of rotavirus group A were identified with increasing age, no correlation was observed between the genotypes and gender (p-value=0.473). Furthermore, there was no significant association between genotype, dehydration rates, and the presence or absence of fever.
Conclusion: This study revealed a relatively high diversity of rotavirus genotypes in children. The findings suggest the need for further research to validate the identified correlations between certain genotypes and age groups, seasonal variations, clinical symptoms, and the efficacy of available vaccines.
