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Showing 2 results for Guideline
Designing an Iran FRAX Model and Defining Intervention and Assessment Thresholds for Osteoporosis
P Khashayar, A Keshtkar, A Ostovar, B Larijani, H Johansson, N Harvey, M Lorentzon, U Mc Closkey , J A Kanis,
Volume 16, Issue 4 (3-2021)
Abstract
Background and Objectives: The purpose of this study was to adopt and calibrate the fracture risk assessment algorithm FRAX® for the Iranian population and to provide the required guidance on how to apply it in clinical practice. 
 
Methods: The age-specific ten-year probability of major osteoporotic fractures was calculated in women with an average BMI to determine the fracture probability at two potential intervention thresholds. The first threshold was the age-specific fracture probability associated with a femoral neck T-score of -2.5 SD and the other was age-specific fracture probability in women with a history of fracture without BMD. Current Iranian guidelines were used to define these thresholds. The effect of adding BMD values to the assessment of these thresholds was also evaluated separately.
 
Results: Similar to women with a previous fracture, the 10-year probability of a major osteoporotic fracture increased from 4.9% at the age of 50 years to 17% at the age of 80 years. When using a BMD T-score of ≤−2.5 SD as the intervention threshold, the FRAX probability was twice as high in women aged 50 years as in women of the same age with an average BMD and no risk factor. The FRAX probability increased with age but a T-score of -2.5 SD was actually protective after 80 years or age.
 
Conclusion: Intervention thresholds based on BMD alone cannot effectively identify high-risk women for fracture, particularly in advanced ages. Using fracture probability based on ‘fracture threshold’ can help to improve the identification of these women.
Introducing Rapid Assessment and Response Approach in High-Risk Populations: A Review of Widely Used Guidelines
Faezeh Joghataei, Payam Roshanfekr, Meroe Vameghi, Zahra Jorjoran Shushtari, Neda Soleimanvandiazar, Peimaneh Shirin Bayan, Gholamreza Ghaedamini Harouni,
Volume 19, Issue 4 (3-2024)
Abstract
Background and Objectives: Rapid Assessment and Response (RAR) is an approach that has been used in health research since the 1990s, and several guidelines have been designed for it. This study examines and compares different guidelines in this field.
Methods: This review study was conducted on the 6 guidelines published in PubMed and Scopus databases. After the initial review, the main dimensions of these guidelines, including the definition and target group, methods used, steps to conduct the research, and time planning were extracted in the form of a comparative table.
Results: In six guidelines, the RAR approach has been defined in relation to the comprehensive and rapid investigation of a health-related problem. There are differences in terms of the number of 'steps' of rapid assessment and response, as well as in 'time planning'; a period of 12 to 16 weeks is considered. Among the methods used in the reviewed guides, the following can be mentioned: reviewing available information, conducting interviews (open, structured, and semi-structured), focused group discussions, and other methods such as observation, surveys, narrative methods, and mapping.
Conclusion: The rapid assessment and response (RAR) can be used as an approach, with high flexibility and consideration of scientific and practical aspects, to assess health problems and high-risk behaviors in hard-to-reach groups.

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