Nanomedicine delivery by microneedle: an emerging technology for disease treatment

Asghari Hosori, Negar; Bagheri, Zeinab

Volume 15, Issue 2 (Volume 15, No 2 2024) jdc 2024, 15(2): 133-144 | Back to browse issues page

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Asghari Hosori N, Bagheri Z. Nanomedicine delivery by microneedle: an emerging technology for disease treatment. jdc 2024; 15 (2) :133-144
URL: http://jdc.tums.ac.ir/article-1-5730-en.html

Nanomedicine delivery by microneedle: an emerging technology for disease treatment

Negar Asghari Hosori¹

, Zeinab Bagheri ^*

1- Department of Cell and Molecular Biology, School of Life Science and Biotechnology, Shahid Beheshti University, Tehran, Iran
2- Department of Cell and Molecular Biology, School of Life Science and Biotechnology, Shahid Beheshti University, Tehran, Iran , ze_bagheri@sbu.ac.ir

Abstract: (254 Views)

The limitations of common needles in drug delivery, such as pain, infection, and side effects, have become a stimulus to search for more efficient alternatives. Meanwhile, microneedles have brought new hope in skin drug delivery. These microstructures are temporarily placed in the upper layers of the skin and provide a painless and non-invasive way for drugs to pass through the skin barrier. Diversity in the design and ingredients of microneedles allows the release of a wide range of drugs with high efficiency and low side effects. On the other hand, nanomedicines are proposed as an ideal alternative due to the limitations of traditional drugs and the need for more targeted and less detrimental options. Nanomedicines are new drug delivery systems that are designed and produced in nanometer dimensions. These small particles can carry and release drugs directly to the target cells with high precision and efficiency. By reducing side effects and increasing the effectiveness of treatment, nanomedicines can play a key role in improving the quality of treatment for various diseases. Considering the unique advantages of the combination of microneedles and nanomedicines, it is an important issue to investigate different strategies for using these new systems in drug release. In this article, this issue has been investigated as well as the applications of nanomedicine transfer by microneedle in the treatment of diseases and the upcoming challenges of this emerging technology.

Keywords: microneedle, nanomedicine, diabetes, cancer, psoriasis

Full-Text [PDF 315 kb] (107 Downloads)

Type of Study: Review | Subject: General
Received: 2024/10/5 | Accepted: 2024/08/5 | Published: 2024/08/5