A review of the efficacy of oral hydrolyzed collagen supplementation on skin aging

Zamani, Erfan; Zamani, Shayan; Nassiri Kashani, Mansour; Firooz, Alireza

Volume 15, Issue 3 (Volume 15, No3 2024) jdc 2024, 15(3): 215-226 | Back to browse issues page

Mendeley

Zotero

RefWorks

Zamani E, Zamani S, Nassiri Kashani M, Firooz A. A review of the efficacy of oral hydrolyzed collagen supplementation on skin aging. jdc 2024; 15 (3) :215-226
URL: http://jdc.tums.ac.ir/article-1-5749-en.html

A review of the efficacy of oral hydrolyzed collagen supplementation on skin aging

Erfan Zamani¹

, Shayan Zamani²

, Mansour Nassiri Kashani²

, Alireza Firooz ^*

1- Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran, Iran * School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2- Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran, Iran
3- Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran, Iran , firozali@tums.ac.ir

Abstract: (58 Views)

This review study examines the effects of oral collagen supplementation on various biophysical properties of the skin, including hydration, elasticity, and wrinkle reduction. Collagen, as the most abundant structural protein in the skin, plays a vital role in maintaining its firmness, elasticity, and moisture. With aging, collagen production declines, leading to visible signs of aging such as wrinkles, sagging, and dryness of the skin. Additionally, factors like UV radiation and environmental pollutants accelerate collagen degradation, contributing to premature skin aging. In recent years, oral supplements containing hydrolyzed collagen, particularly collagen peptides, have gained significant popularity due to their potential ability to stimulate collagen production and improve skin quality. Various studies indicate that regular consumption of these supplements can significantly increase skin hydration, enhance elasticity, and reduce the depth and number of wrinkles. However, there are notable limitations in the existing studies, including variations in dosage, intervention duration, and collagen sources. Moreover, many of these studies have small sample sizes and short intervention periods, which limit the validity of the results. Additionally, the presence of other ingredients, such as vitamin C and hyaluronic acid in some supplements, makes it challenging to isolate the direct effects of collagen. Despite these challenges, the existing evidence suggests that oral collagen supplementation holds high potential as an effective approach for addressing skin aging. However, further long-term studies with larger sample sizes and more diverse populations are necessary to determine the precise mechanisms and optimal dosage, thereby providing more definitive scientific recommendations.

Keywords: skin aging, skin wrinkling, collagen, dietary supplements

Full-Text [PDF 705 kb] (43 Downloads)

Type of Study: Review | Subject: General
Received: 2024/12/29 | Accepted: 2024/11/5 | Published: 2024/11/5