Showing 15 results for Ahmadi
Mehraban Falahati, Zeinab Ghasemi, Shirin Farehyar, Ebrahim Eskandari, Mahtab Ashrafi, Farzaneh Ahmadi, Gholamhossein Ghaffarpour,
Volume 3, Issue 2 (6-2012)
Abstract
Background and Aim: Onychomycosis is the fungal infection of nails. Patient’s immune system has an important role in initiation of onychomycosis. One of the causes of the increased prevalence of onychomycosis is the increasing number of patients with local or general immune system disorders. In hormonal disorders such as diabetes mellitus, Cushing's syndrome and hypothyroidism superficial vascular disorders and individuals with immune deficiency, onychomycosis prevalent. The aim of this study was to investigate onychomycosis in individuals with underlying diseases who referred to Razi hospital in Tehran.
Methods: In this cross-sectional study, nail specimens of 250 patients who have nail dystrophy with an underlying disease whom were referred to mycological laboratory of Razi hospital in 2010-11 were evaluated with direct microscopy and culture on Sabouraud dextrose agar and Sabouraud dextrose agar containing chloramphenicol and cyclohexamide. For differential diagnosis of fungi, complementary tests were used.
Results: Eighty-nine (35.6%) of 250 individuals with underlying diseases and nail dystrophy, were affected with onychomycosis. Among these pateints, 52 (58.4%) cases had yeast infection, 19 (21.3%) had dermatophyte infection, and 18 (20.2%) had saprophyte infection. Diabetes mellitus (37.1%), cardiovascular diseases (14.7%), pemphigus (9%), psoriasis (7.9%), hypothyroidism (6.7%) and chronic eczema (5.6%) were the most common underlying diseases observed in patients with onychomycosis.
Conclusion: Onychomycosis is common in hormonal disorders like diabetes mellitus and hypo-thyroidism superficial vascular disorders and individual who suffer immunodeficiency.
Lida Bahrami, Hamze Ahmadian, Gholamreza Eshghi,
Volume 5, Issue 3 (Volume 5, Number 3 2014)
Abstract
Background and Aim: Vitiligo is a common skin disease and it is important to recognize and manage its social and psychological consequences. The aim of this study was to investigate the relationship between illness perception, depression and quality of life among vitiligo patients referred to the skin clinic of Farshchian Hospital in Hamedan.
Methods: This cross sectional study was conducted on the patients with vitiligo referred to the skin clinic of Farshchian Hospital during the first quarter of 2014. The study sample consisted of 100 patients (32 male and 68 female patients) with vitiligo who were selected using convenience sampling. Measurement tools included the Revised Illness Perception Questionnaire (IPQ-R), World Health Organization Quality of Life-BREF (WHOQOL-BREF), and Beck Depression Inventory-II (BDI-II). The data were analyzed using Pearson's correlation test.
Results: Illness perception have significant relationship with depression and quality of life in vitiligo patients. There was a significant difference in positive (P=0.031) and negative (P=0.002) illness perception scores between male and female vitiligo patients. Also, environmental dimension of quality of life in vitiligo patients was significantly different between men and women (P=0.031).
Conclusion: Evaluation of quality of life and depression in patients with vitiligo to reduce the adverse consequences of the disesase on patients' lives is recommended.
Zeinab Ghasemi, Mehraban Falahati, Farideh Zaini, Gholam Hossein Ghaffarpour, Farzaneh Ahmadi, Seyed Ebrahim Eskandari,
Volume 6, Issue 2 (Volume 6, Number 2 2015)
Abstract
Background and Aim: Tinea unguium is a common disease with worldwide distribution most commonly seen in adult patients. Trichophyton rubrum and T. interdigital are the most common causes. The aim of this study was to investigate the frequency of tinea unguium causative agents in a referral dermatology hospital in Tehran, Iran.
Methods: This cross sectional study was conducted in 2010 and 2011 on clinically suspicious patients for tinea unguium referred to the Mycology Laboratory, Razi Hospital, Tehran, Iran. Samples from 700 patients were examined using direct smear microscopy and culture. Direct microscopic examination of the specimens was carried out using 20% potassium hydroxide solution. The specimens were cultured on Sabourad dextrose agar culture media containing chloramphenicol and cyclohexamid (Scc). For identifying the species of dermatophytes, complementary tests were used. Frequencies and relative frequencies were demonstrated in tables and chi-square and Fisher's exact tests were used to investigate any association between the categorical variables.
Results: Of 700 dystrophic nail samples, 53 samples (7.6%) were positive according to both direct examination and culture. Thirty-eight patients were males. The most common clinical type was distal subungual onychomycosis which was observed in 79.2% of cases. The most frequent detected dermatophyte species. was T. interdigital (39.6%) followed by T. rubrum (37.7%). Forty-seven patients had tinea unguium on their toe nails, 4 patients on their finger nails, and 2 patients had it on both finger and toe nails. Nineteen patients had underlying diseases, and the most common underlying disease was cardiovascular disease (26.3%).
Conclusion: Tinea unguium is a disease with worldwide distribution and identifying the causative agents and predisposing factors are necessary for better management of the patients.
Shokoufeh Ahmadi Moghadam, Roghieh Jebreili, Masoumeh Yarjanli,
Volume 7, Issue 2 (Volume 7, Number 2 2016)
Abstract
Background and Aim: Hair loss is a common issue among men and women. Studies have shown that 1-25 (OH) vit D affects differentiation in normal follicles and hair growth, through effect on the translation of genes. The aim of this study was to assess vitamin D3 level in patients suffering from hair loss between the age of 18 to 50 years.
Methods: This cross sectional study was conducted on 100 patients including 27 men and 73 women suffering from hair loss. Cases were chosen from one of the educational hospitals of Islamic Azad University, Tehran Medical Branch. Blood samples were obtained from the patients and were sent to the laboratory for assessment of vitamin D3 serumic levels.
Results: The average of patients’ age was 29.5±8.5 years. The average serum level of vitamin D in patients was 17.26±14.5 ng/mL. Sixty-six percent of patients suffering from hair loss had vitamin D deficiency as well. The prevalence of vitamin D insufficiency in women was considerably more than men (P<0.001).
Conclusion: Prevalence of vitamin D deficiency among people suffeing from hair loss is noteworthy.
Narges Bidhendi, Hamidreza Ahmadi Ashtiani, Azin Ayatollahi, Somaye Yadangi, Orkideh Ghorban Dadras, Alireza Firooz,
Volume 7, Issue 4 (Volume 7, Number 4 2017)
Abstract
Background and Aim: Dandruff and seborrheic dermatitis (SD) are common chronic skin diseases. There are many chemical drugs for treating dandruff and SD. Prolonged use of them may cause side effects and drug resistance. The aim of this study was to compare the efficacy of a herbal extract lotion with clotrimazole 1% lotion in the treatment of SD.
Methods: Twenty volunteers (12 men and 8 women) aged 20 to 40 years, with seborrheic dermatitis were enrolled in this trial and were randomly allocated into two groups. One group was treated with a herbal extract lotion and the other group with clotrimazole lotion. The herbal extract contained common sage, thyme vulgaris, tea tree oil, lavender, willow, rosemary, and aloe vera. The patients were instructed to use the lotions three times a week for 4 weeks. We evaluated the patients by clinical assessment and measured the scalp sebum, pH, and dandruff number before two weeks, and four weeks after completed a treatment. At the end of the study, each participant satisfaction form.
Results: At the end of the study, the participants whom received the herbal extract lotion had a significantly greater reduction in scalp scaling, erythema, itching, and number of dandruff compared with those who received clotrimazole (P<0.05). The patient satisfaction score was also higher in the herbal extract group (60% versus 10%).
Conclusion: This study showed that herbal extracts lotion was effective in the treatment of dandruff and seborrheic dermatitiand can be an appropriate alternative to chemical agents.
Monireh Ensaf, Masoome Khanahmadi, Shahla Mirzaee,
Volume 9, Issue 1 (2018, Volume 9, Number 1 2018)
Abstract
Background and Aim: Shampoos are products that remove fat and dust from the hair and scalp. Cleansing and decontamination are the most important properties of a shampoo for its acceptance. To create a stable foam in shampoos, alkaloids are often used which are believed to be carcinogens due to production of nitrosamines. Hence, the main goal of this study was the production of shampoo by using medicinal plants.
Methods: In this study, herbal shampoos were prepared by using aqueous and hydro-alcoholic extracts of Yarrow, Cedar, Chubak and licorice as surfactants, and Katira as thickener. Then their physical and chemical properties were analyzed.
Results: After preparing the herbal base shampoo, the physical and chemical evaluation of the product was performed. We found that this formulation had cleansing power for foam formation, antimicrobial and antifungal properties, and also a high shelf life compared to the control sample (chemical shampoo). It also didn’t have any adverse effect on hair and scalp of consumers. The present formulation is also suitable for commercial shampoo production.
Conclusion: The herbal based shampoo had better qualitative properties than the chemical base, and the use of the aqueous extract of the aforementioned plants (compared to their hydro alcoholic extracts) had better performance and was economically feasible.
Rahele Ahmadi, Ilnaz Sajjadian, Fariba Jaffari,
Volume 10, Issue 1 (2019, Volume 10, Number 1 2019)
Abstract
Background and Aim: Vitiligo is a depigmenting skin disorder, which has a great impact on the psyches of patients. The present study aimed at investigating the effectiveness of compassion-based treatment on anxiety, depression, and suicidal ideation of women with vitiligo.
Methods: This study was designed as a pre-test and post-test semi-experimental with a one-month follow-up and control group. Thirty patients of all vitiligo women (n=80) referring to Skin Diseases and Leishmaniasis Research Center (SDLRC) during 2016-2017 (n=80) were selected for this study and randomized in 2 groups: all participants were assessed for anxiety and depression using Hospital Anxiety and Depression Scale (HADS), Zigmond and Smith (1983), suicidal through Beck Scale for Suicide Ideation (BSS), (1997) before intervention, at the end and one month after intervention. The experimental group attended in 8 consecutive 60-minute session group - based compassion - focused therapy (CFT, Gilbert and Neff therapeutic Package 2009) biweekly. Control group did not receive any intervention until the end of the follow-up phase. Repeated measure analysis of variance was used for data analysis.
Results: The results showed that compassion-focused therapy was effective on anxiety, depression, suicide ideation compared to control group.
Conclusion: According to the results of this research, compassion-based therapy has been effective in reducing anxiety, depression, and suicidal ideation.
Hamidreza Ahmadi Ashtiani, Alireza Firooz, Hossein Rastegar, Amirhosein Askaripour,
Volume 10, Issue 4 (Volume 10, No4 2020)
Abstract
A wound is described as any laceration in normal anatomic structure and functional integrity of the skin. Chronic wounds don’t progress through the normal wound healing process in 3 months leaving open laceration of different degrees of severity. Diabetic wound healing is an insurmountable process due to the chronic nature of diabetic wounds. For these complications, this has been a challenge in the health care system. By the appearance of regenerative medicine, advisedly stem cell-based therapies and ingredients have been gained the focus of researchers and professionals as well. As there is no definite cure for diabetic wounds and forasmuch as the appearance of regenerative medicine and cell-based therapies there is a big hope to find a definite treatment for diabetic wounds. In this article novel therapies based on stem cells were observed.
Hamidreza Ahmadi Ashtiani, Amirreza Noori Garmroodi, Alireza Firooz,
Volume 11, Issue 2 (Volume 11, No2 2020)
Abstract
Wounds are any type of tissue dehiscence which can occur on skin, mucosae or connective tissue. After the wound has created, inflammatory process, the immune system changes as well as the skin repair cascade will be activated. To provide a product that can direct the above processes in a desirable repair mechanism will be useful. Studies have shown that aloe vera products, with effects such as increased collagen production, antioxidant and water retaining properties, are good options.
Aloe vera grows mainly in arid regions and this fact can be welcomed in many parts of the world. The use of medicinal herbs also reduces the cost for the health systems. Aloe vera is a plant that does not require much cost for plant and harvest. Besides, the compatibility of aloe vera products with a variety of formulations encourages formulators to use it in the pharmaceutical and cosmetic industries.
In this review, the use of aloe vera in wound management and some skin diseases will be discussed.
Aniseh Samadi, Hasti Ahmadianyazdi, Maryam Ahmadi, Atefeh Naeimifar, Saman Ahmadnasrollahi, Alireza Firooz,
Volume 12, Issue 4 (Volume 12, No 4 2022)
Abstract
Background and Aim: Although several commercial moisturizers are available in the market, continued role of pharmaceutical compounding have been still felt in dry skin management. This study aimed to evaluate the effect of a two urea- based compounded moisturizers on barrier function, compared to similar commercial product. 15 volunteers (14 females and one male) age 36.15 ±9.55 years old (range 21-56 years old) with non-pathologic dry skin, recruited to the study applied 5% urea containing hydrophilic petrolatum and 10% urea containing hydrophilic petrolatum during two following phases.
Methods: Upper parts of right and left forearms randomly were assigned for twice a day application of commercial or compounded products. Biophysical assessments including trans epidermal water loss (TEWL), skin hydration, friction co efficient, pH and surface lipids, performed before intervention, 1, 4 after single application and at 24 hours and one week twice daily application.
Results: In both phases, commercial and compounded moisturizers showed appropriate and comparable effect on skin barrier function compared to the baseline. However commercial products, led to better improvement in TEWL, 4 hours after single application in both phases (P=0.04). The rate of increase in skin hydration was also significantly higher for commercial emollient, compared to compounding product (57.48±11.23 vs. 50.59±11.42, P=0.01).
Conclusion: Commercial formulation led to higher acceptability and better improvement on skin barrier function after single application, probably due to influence of excipients. Present study did not find sufficient added value for pharmacy product relative to commercial one and suggest to be replaced in similar condition.
Akram Miraminmohammadi, Minoo Tasbihi, Seyedebrahim Eskandari, Maryam Ahmadi,
Volume 12, Issue 4 (Volume 12, No 4 2022)
Abstract
Leishmaniasis is a neglected disease caused by different Leishmania species and transmitted by various sand flies. Iran is endemic to both visceral and cutaneous form of the diseases. The aim of this study was to investigate the epidemiological factors of leishmaniasis in patients referred to the Center for Research and Training Skin Disease and Leprosy from 1399-1400. The present study is a cross-sectional study in which every patient with suspected cutaneous leishmaniasis lesion(s) referred to the center during 1399-1400 were included. The results showed a higher number of patients with leishmaniasis are in the age group of 10 to 19 years. Among the mentioned jobs, a higher percentage was assigned to housewives in the affected women and workers in the affected men. According to the results, autumn is the most common season for cutaneous leishmaniasis. The average time from beginning to the diagnosis of leishmaniasis was 1.5-3 months and most patients showed a history of traveling to rural areas. The number of wet type lesions were higher than dry type and most of the lesions were in the hands. Most cases were reported from Isfahan province.
Seyedebrahim Eskandari, Ali Khamesipour, Alireza Firooz, Minoo Tasbihi, Akram Miraminmohammadi, Khadijeh Tavakoli, Maryam Ahmadi,
Volume 13, Issue 2 (Volume 13, No 2 2022)
Abstract
Background and Aim: Leishmaniasis is a parasitic disease transmitted by sandflies and is one of the endemic diseases of Iran. With the spread of the Covid-19 epidemic worldwide, the virus will interface with endemic infectious diseases in different regions. In this study, coronavirus disease was evaluated in patients with a history of leishmaniasis referred to the Center of Research and Training in Skin Diseases and Leprosy.
Methods: A total of 91 patients with a history of leishmaniasis were studied for possible SARS-CoV-2 infection. The number of patients referred to the Center of Research and Training in Skin Diseases and Leprosy during the coronavirus epidemic was also compared with the same period before the epidemic
Results: A total of 60% of patients with leishmaniasis
did not report coronavirus disease. Twenty-one percent of cases had a mild corona disease, 13% had a moderate and 3% had severe corona disease. Only a single death was reported in corona patients with a history of cutaneous leishmaniasis. The number of referrals before the beginning of the corona epidemic was twice as high as during the epidemic.
Conclusion: In these participants, mortality and side effects of COVID-19 were significantly less reported. However, further studies are needed to evaluate the immune system and cutaneous leishmaniasis protection against COVID-19. Various factors can be effective in reducing patients during the epidemic, including not going to medical centers, reducing the number of trips, and observance of health issues.
Hasti Ahmadian Yazdi Ahmadian Yazdi, Alireza Firooz, Maryam Movafegh, Faegheh Kazemi, Saman Ahmadnasrollahi, Aniseh Samadi,
Volume 13, Issue 4 (Volume 13, No 4 2023)
Abstract
Background and Aim: Oral hydrolyzed collagen is one of the newest and most popular systemic supplementations for skin rejuvenation. However, there are limited information in case of Middle Eastern consumers. The purpose of this study was to evaluate the tolerability and efficacy of an oral collagen supplement for improvement of skin elasticity, hydration and roughness.
Methods: It was a 12-week, before-after clinical study, conducted on 20 participants (18 women and two men) aged 44.15±5.36 years with skin type III-IV. Skin elasticity parameters (R0, R2, R5 and R7), skin hydration and friction, as well as the thickness and echo density of the dermis, were measured after six and 12 weeks daily intake of the study product, as well as four weeks after stopping its use (week 16). Participants’ satisfaction was assessed on the basis of their answers to the standard questionnaire, and tolerability of the product was assessed by monitoring the adverse effects.
Results: A significant improvement was detected in R2, R5 and skin friction at week 12 (P<0.041, P<0.012 and P<0.01, respectively). At week 16, the values remained at an increased level, which indicates the stability of the results. The increase of dermis density in week 16 was also significant (P=0.03). Moderate overall satisfaction was reported with the treatment, and a few gastrointestinal complications were reported.
Conclusion: The study demonstrated that oral collagen peptides could significantly improve the skin elasticity, roughness, and dermis echo density, and they also proved to be safe and well-tolerated.
Hatam Ahmadi, Arina Nikkhah,
Volume 14, Issue 1 (Volume 14, No 1 2023)
Abstract
The human face is the main source of information transmission for many non-verbal messages, including the emotional state of a person. Botox or botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum that grows and reproduces in canned foods. There are 8 serotypes of this toxin, the B type is mainly used clinically to treat a wide range of disorders and diseases, and the A type is used for cosmetic purposes. Repeated injections of Botox are necessary to maintain its therapeutic effects. Botox injection in the muscles located under the wrinkles of the face causes them to relax and as a result the skin of that part becomes smooth. Botox injection in therapeutic or cosmetic cases is relatively safe and can be an alternative method to the use of drugs or surgery. Although the frequency of serious side effects for the use of Botox in medical cases is much higher than in cases of cosmetic use. However, the use of Botox in beauty may also have side effects that can be avoided by following different techniques.
Hasti Ahmadian Yazdi, Alireza Firooz, Mohsen Rezaeian Vaghar, Elahe Kashani, Aniseh Samadi,
Volume 14, Issue 2 (Volume 14, No 2 2023)
Abstract
Background and Aim: In order to overcome the local side effects of the conventional treatments for atopic dermatitis, a new attitude regarding alternative treatments would be needed, which herbal medicines are promising approachs in this case.
Methods: It was a 4-week, before-after clinical study, conducted on 20 participants (16 women and 4 men) aged 39.95±11.04 years. The severity scoring of atopic dermatitis was determined based on total & local SCORAD. skin biophisical parameters including TEWL ,skin hydration, pH, temperature, sebum and skin erythema were also measured after 2 and 4 weeks application of the study product. Participants’ satisfaction as well as tolerability of the product were assessed by monitoring the adverse effects.
Results: A significant improvement was detected in LOCAL and TOTAL SCORAD at weeks 2 and 4 (P<0.01). The intensity of burning and pruritus also showed a significant decrease at weeks 2 and 4 (P<0.01). A significant increase in the skin hydration was shown at weeks 2 and 4 after treatment (P<0.01). 84.1% and 78.9% of participants described their skin lesions as "improved" or "much improved", 2 and 4 weeks after treatment respectively.
Conclusion: The test cream containing oats and chamomile extract is considered a safe and effective product for improving mild to moderate lesions of atopic dermatitis.
