Journal of

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Hair loss can be viewed a problem from different perspectives: as a disease, a disorder which affects appearance of an individual, and its psychological effects. Therefore, it is crucial to determine the causes and types of hair loss. This review summarized hair loss evaluation methods with significant emphasis on their clinical aspects. According to relevant literature reviews, the major approaches to hair loss are taking medical history, primary investigations and detailed hair examination. Although several invasive and non-invasive, clinical and paraclinical examinations can be used for hair loss assessment, it is generally accepted that using clinical evaluation methods and physical examinations are more efficient. In conclusion, diagnosing hair loss is complex and sometimes time-consuming process. However, precise hair examination may lead to the suspicion of an endocrine disorder.

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Background and Aim: Thalassemia is one of the most common single gene disorder that results from decrease or absence of globulin chain(s) synthesis. Repeated blood transfusion is required for prevention of severe anemia and related side effects, but it is associated with other complications such as cutaneous lesions and mucosal manifestations. This study conducted to assess the frequency of cutaneous and mucosal manifestations in patients with beta thalassemia.
Methods: This cross-sectional study was conducted on 300 patients with beta major thalassemia in Zahedan. Data were obtained from medical records and questionnaires as well as through physical examination of patients. The data were statistically described and tested.
Results: The mean age of patients was 17.9±6.3 years and 64.3% of patients were men and 35.7% were women. Among cutaneous lesions, freckles were the most common (70.7%) and the rarest one was peri orbital pigmentation (0.3%). Gingivitis (41.7%) and longitudinal lines on nails (72%) were the most common mucosal and nail manifestations.
Conclusion: Since cutaneous and mucosal manifestations are very common among patients with beta major thalassemia, regular dermatology follow up of these patients is recommended.

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Osteoma cutis is a rare benign disease characterized by the presence of osseous nodules in the dermal layer of the skin. The cause of osseous depositions is unknown still. It may be primary or secondary. Herein, we reported a 55-year-old woman that presented with multiple skin color papules on her face.

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Introduction: Egyptian cockroach is one of the species of cockroaches, which has a worldwide distribution, and can live in closed human environments. In this paper, we present the first reported patient with skin reactions and dermatitis to Egyptian cockroach in Iran.

Case Report: An 80-year-old man referred to the clinic with skin lesions on his right foot. The patient lived in an adobe house in Rafsanjan city, and he had not past history of skin lesions. He reported severe itching at the beginig,one day later redness and swelling appeared. Physical examination, revealed inflammation and bite signs. Lesions disappeared after two weeks of medical treatment.

Conclusion: In general, cockroaches can cause skin reactions after body contact, so public knowledge and awareness about the prevention and control of these cockroaches should be increased in the community.

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Bed bug (Cimex lectularius) is an nocturnal insect that feeding on human blood at all stages of them life, and known as a human ectoparasite. Bed bug is usually feeding from the face, neck, arms, arms, shoulders, legs, and especially parts of the body that are bare during sleep. Persons reaction differently to bed bug bites and may experience minor itching to severe allergies. Symptoms usually appear after 1 to 24 hours and usually include small red cluster papules less than 5 mm in diameter and at a short distance from each other, with severe inflammation and itching. In general, the most important characteristic of those three points is a linear or curve sequence on the body, which is called “breakfast, lunch and dinner” pattern. There are numerous reports of house infestation and the bite of this blood-feeding insect on the body of persons in the country annually, and in initial the majority of the public is unable to correctly identify the symptoms of bed bug bites. So, this article by presenting the key points can be guide for identifying the bite symptoms of this allergenic insect, by doctors and specialists, especially dermatologists, for the timely treatment of the patient.

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Background and Aim: Cicatricial (scarring) alopecia is a group of disorders in which permanent hair loss results from replacement of hair follicles by fibrosis or hyalinized collagen, which includes two types: primary such as discoid lupus erythematosus (DLE), lichen plano pilaris (LPP), frontal fibrosing alopecia (FFA), Folliculitis decalvans, and secondary like kerion and burn. The aim of this study was to evaluate the frequency of different types of scarring alopecia in patients referred to Imam Reza Dermatology Clinic in Ardebil in 1397.

Methods: In this descriptive cross-sectional study, 96 patients referred to the dermatology clinic of Imam Reza Hospital, Ardebil, Iran, were evaluated. Epidemiologic and pathologic causes of primary and secondary cicatricial alopecia were analyzed using descriptive statistics in SPSS version 16 software.

Results: The most common causes among patients with primary cicatricial alopecia were DLE (51.16%), LPP (6.25%), acne keloidalis (4.16%), folliculitis decalvans (2.08%), FFA (2.08%) and pseudopelade of Brocq 1.04%). In patients with secondary cicatricial alopecia the most common causes were kerion (55.2%), followed by morphea cutaneous lymphoma and burn (1.04%).

Conclusion: Considering that the majority of patients in rural area had kerion (92.45%), we can prevent the spread of the disease by improving hygiene standards as an important factor in controlling this disease in order to early diagnosis and treatment.

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Introduction: Fleas are small, blood-sucking insects that can transmit some pathogens to human and animals.

Case Report: This paper presents a 21-year-old woman with severe skin reactions in her right forearm. After initial examinations, the symptoms were recognized as skin reaction caused by the bite of some human blood-sucking insects. Finally, after 15 days of flea bites, the symptoms were treated with topical after bite cream and oral antihistamines. In order to prevent and control the infestation of this blood-sucking pest, public awareness should be increased specially in at risk populations.

Conclusion: Increasing awareness among physicians, about the symptoms of this health pest can help to accelerate treatment process.

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Background: Tarantulas (Camel spiders) are order that belong to classes of arachnida and phylum of arthropoda. They can make a painful bite in human.
 

Case Report: This paper presents 34 and 40-year-old men with skin reactions in their left legs. After initial examinations, the symptoms were recognized as skin reaction caused by the bite of some nuisance insects. After one day, a lesion including 2 red dots appeared on the patient's leg. After a few hours, skin lesions were observed in both patient, and by washing with soap and water after 7 days, the symptoms completely disappeared and the bite improved.
 

Conclusion: Increasing awareness among physicians, about the symptoms of this nuisance insects can help to accelerate treatment process.

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Virtually all deaths in young patients with advanced skin tumors are caused by melanoma. Today, thanks to modern treatments, these patients survive longer or can even be cured. Advanced melanoma is often associated with a poor prognosis, and physicians continue to believe that the disease is difficult to treat due to the lack of durable response to initial treatment regimens and the lack of randomized clinical trials in the post-immunotherapy/targeted molecular therapy setting. New therapeutic targets are emerging based on preclinical data on the genetic profile of melanocytes and the identification of molecular factors involved in the pathogenesis of malignant transformations. In this article, we present the challenges of diagnosis, molecular biology and genetics of malignant melanoma, as well as current treatment options for patients with this diagnosis.

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Background and Aim: Spiders are one of the largest orders of arachnids, found worldwide on all continents except Antarctica. Many species of spiders live in close proximity to humans and generally inject poison into other animals, including humans, to protect themselves or to hunt.
Case Report: In this paper, a seven-year-old boy is presented who came to the hospital complaining of skin reactions in the eye, knee, and lower leg area. Skin lesions appeared on the boy's body after a few hours. After 24 hours, the skin lesions intensified, and inflammation and redness along with itching occurred on the boy's body. Finally, after 5 days, the skin lesions disappeared completely by washing with soap and water along with the use of Calamine lotion and the bite site improved.
Conclusion: Increasing awareness among physicians, about the symptoms of this nuisance insects can help to accelerate treatment process.