Journal of

Background and Aim: The aim of this study was to evaluate surgery approach outcomes in patients with squamous cell carcinoma (SCC) of lower lip.

Methods: We retrospectively analyzed medical records of patients that diagnosed with SCC of the lower lip at Razi hospital at Tehran University of Medical Sciences in a 5 year period. Data analysis included descriptive statistics and bivariate analyses using the chi-square and Fisher’s exact tests to compare the variables.

Results: The age range of patients was 35 to 94 years (mean, 64.1 years; SD, 13.27 years), with a 5:1 male-female ratio. SCC of the lower lip occurred more frequently in patients older than 60 years. 62.1 % of the patients were addicted to cigarette and other tobacco compounds. It was noted
sig­nificant association between chronic solar exposure in the job’s environment and incidence of SCC in lower lip. Mean diameter of the tumor was 28.1 mm (range, 5 to 63 mm). Recurrence was detected in 17 patients (24.6%). Two patients (2.89%) died due to lower lip SCC in this series.

Conclusion: our study revealed that lower lip SCC is more prevalent in men and in eighth decade of life. As well, considering the low recurrence rate and high survival rate, surgery could be considered as an effective method of treatment.

Background and Aim: The present study aims to assess the prevalence of obstructive sleep apnea in patients with psoriasis referring to Razi Hospital.
 

Methods: Participants were assessed for demographic characteristics, Psoriasis Area and Severity Index (PASI), disease duration, place of residence, education level, and were also evaluated using the Stop-Bang and Berlin questionnaires to assess the risk of obstructive sleep apnea. The high and low-risk groups for obstructive sleep apnea were compared regarding these parameters.
 

Results: Based on the Stop-Bang criteria, 43 individuals (41.3%) had moderate risk, and 23 individuals (22.1%) had high risk of obstructive sleep apnea. According to the Berlin questionnaire, 48 individuals (46.2%) were at high risk for obstructive sleep apnea. The mean age of individuals with high risk of obstructive sleep apnea according to the STOP-BANG criteria was significantly higher than those with moderate risk (mean=58.3, standard deviation=10.6, compared to mean=48.1, standard deviation=16.1, P = 0.039) and low risk (mean=41.7, standard deviation=17.8, P< 0.001). Additionally, BMI differed significantly among the three groups based on the Stop-BANG criteria, with higher BMI observed in individuals at higher risk for obstructive sleep apnea (P<0.05). BMI was significantly higher in individuals with high risk of obstructive sleep apnea according to the Berlin criteria compared to those with low risk (mean 31.1 versus mean 26, P<0.001).
 

Conclusion: The findings of this study highlight obstructive sleep apnea as a comorbidity associated with psoriasis.