Showing 5 results for Ghaderi
Azin Ayatollahi, Pegah Tamimi, Aliasghar Ghaderi, Mahsa Fattahi,
Volume 14, Issue 4 (Volume 14, No 4 2024)
Abstract
Recently, the cases of dermatophytosis have increased sharply, which is associated with frequent reports of chronic cases of the disease, uncommon skin manifestations, and treatment failure. Cases of emergence of resistant species in other geographical areas such as Denmark, Switzerland, and China, Belgium, Germany, Japan, Iran, Finland, Switzerland, France, Iraq and Bahrain are also known. Antifungal drug susceptibility testing for dermatophyte species has not yet been standardized. Antifungal Susceptibility Tests (AFST) are used to determine the minimum growth inhibitory concentration (MIC) of a specific drug in laboratory conditions with the aim of predicting whether a patient will respond to standard antifungal treatment or not. In the continuation of this article, we gave an overview of the antifungal sensitivity test, including its strengths and weaknesses and its role in helping to make therapeutic decisions.
Pegah Tamimi, Parham Tamimi, Aliasghar Ghaderi,
Volume 14, Issue 4 (Volume 14, No 4 2024)
Abstract
Dysregulation of long non-coding RNA may lead to various diseases including cancer. Recently, many lincRNAs have been discovered for their important roles in melanoma, cutaneous squamous cell carcinoma (SCC), and basal cell carcinoma (BCC). These long non-coding RNAs are involved in skin cancer cell proliferation, angiogenesis, invasion, and metastasis.
Some long non-coding RNAs are upregulated in Non-melanoma Skin Cancer (NMSC), including PICSAR, PRECSIT, LINC01048, MALAT1, LINC00319, AK144841 in SCC and H19, CASC15, SPRY4-IT in BCC. In contrast, some long non-coding RNAs are down-regulated in SCC, including TINCR, SMRT-2, and LINC00520.
Many non-coding RNAs are specifically expressed in certain tissues or cells, and others are associated with tumor staging, drug resistance, and prognosis. Hence, non-coding RNAs can be used as diagnostic and prognostic tools in skin cancers.
Seyedmohsen Mohebi Nodez, Alireza Zare Karizi, Bita Ghaderi, Shahrazad Aghababaei, Ismaeil Alizadeh,
Volume 15, Issue 3 (Volume 15, No3 2024)
Abstract
Background: Scorpions are known as one of the oldest venomous animals on the planet. Scorpion bites are an important public health problem in many parts of the world, including Iran.
Case Report: In this paper, a 49-year-old woman is presented who came to the hospital with a complaining of skin reactions in the thigh area. The clinical findings in this study showed that the scorpion bite site had inflammatory reactions and redness after 24 hours. The patient was treated with Pentavalent anti-scorpion serum by intravenous injection. Approximately one week after the scorpion bite, the local and systemic symptoms disappeared with the use of anti-inflammatory ointments. Immediately after the scorpion bite, the patient's resting place was checked by the companions, and a specimen of the Hottentotta jayakari scorpion species was identified.
Conclusion: Considering that there are scorpion bite in Iran, in order to prevent and control them, it is necessary to increase the general awareness and knowledge of people at risk in society in order to reduce possible risks. In addition to these, increasing the awareness among doctors, especially dermatologists, of the skin symptoms of this dangerous animal, as therapists, can help speed up the treatment process.
Azin Ayatollahi, Aliasgahr Ghaderi,
Volume 16, Issue 1 (Volume 16, No 1 2025)
Abstract
The indications for botulinum toxin have evolved tremendously since its introduction in 1989. This review highlights the potential of the use of BoNT based on the latest studies that indicate botulinum toxin injections may be beneficial as an alternative method of therapy in treating, among others, hyperhidrosis, hidradenitis suppurativa, Raynaud phenomenon, or anal fissure. Currently, there are numerous studies suggesting the effectiveness of botulinum toxin in the discussed diseases; however, it should be emphasized that the majority of evidence is based on low scientific quality publications and more clinical trials need to be conducted. Despite many favorable utilizations, the use of botulinum toxin is not without ramifications. To serve patients with relevant therapy and reduce related complications, dermatologists should be aware of both on- and off-label applications of botulinum toxin. Undoubtedly, a consensus on the treatment protocol for each indicator should be a topic of interest for practitioners to standardize all regimens with specific doses of BoNT.
Pegah Tamimi, Aliasghar Ghaderi, Parham Tamimi,
Volume 16, Issue 2 (Volume 16, No 2 2025)
Abstract
This article reviews the impact of Menopausal Hormone Therapy (MHT) and oral contraceptives on melanoma risk. While some studies suggest an association between MHT and melanoma, conflicting evidence exists, including differences in drug formulations across countries, age at the start of treatment, and duration of use. Most studies have found no connection between oral contraceptive use and an increased melanoma risk, though environmental factors like sun exposure may play a role in this relationship. Overall, it appears that women should continue hormone therapy based on their healthcare provider’s advice, without specific concerns about melanoma risk.
