Showing 5 results for Hallaji
Amir Houshang Ehsani, Mostafa Mirshams Shahshahani, Zahra Hallaji, Pedram Noormohammadpour,
Volume 1, Issue 1 (3-2010)
Abstract
Background and aim: Actinic keratoses (AKs) are the third commonest complaint of patients visiting dermatologists. Topical treatment including 5-fluorouracil (5-FU) are among the commonest available therapies. According to local irritation induced by topical 5-FU The aim of current study was to compare efficacy of two different 5-FU based regimens with different application routes.
Methods: Patients with AKs confirmed by skin biopsy, matching our exlusion criteria were enrolled. Subjects randomized in two groups, receiving topical 5% 5-FU once daily or alternatedaily respectively. Two weeks after the end of one month period of the study, rate of reduction in number of lesions was documented by blinded academic dermatologists as well as treatment side effects.
Results: a total of 38 patients (23 male and 15 female) completed the study. Rate of side effects were lower in alternate-day applying patients (P<0.05) while rate of response to therapy were comparable in both groups (P>0.05).
Conclusion: alternate-day route for application of topical 5-FU is an acceptable alternative for classic daily application, to reduce rate of side effects and enhancing patients compliance.
Masoumeh Barzegari, Zahra Hallaji, Amirhoushang Ehsani, Pedram Nourmohammdpour, Maedeh Parham,
Volume 1, Issue 2 (6-2010)
Abstract
Background and Aim: Psoriasis is a chronic skin disorder involving many parts of the body including skin, nails and joints with severe negative effects on patient's quality of life. Nail involvement is one of the most difficult involvements of this disease to treat. Psoriatic arthritis categorized in sero-negative spondilo-arthropaties with some deforming characteristics. The aim of the present study was to evaluate the relationship between psoriatic arthritis and nail involvement based on standard psoriatic nail involvement score (NAPSI).
Methods: Psoriatic patients visiting dermatology clinic of Razi hospital were selected. Patients with arthritis enrolled as the case group while patients that had no joint involvement participated in control group. After matching, demographic data of both groups as well as NAPSI score and nail involvement characteristics collected through special questionnaires and analyzed with SPSS version 14.
Results: A total of 30 patients with psoriatic arthritis and 75 patients without arthritis were enrolled the study. Analysis of collected data demonstrated that nail involvement among patients with psoriatic arthritis (mean NAPSI score=46) was more common and severe than patients without joint involvement (mean NAPSI score=9.23) (P<0.05).
Conclusion: It seems that there is a significant difference between psoriatic patients presenting with or without arthritis and presence of arthritis probably can determine occurrence and extension of nail involvement.
Zahra Hallaji, Maryam Akhyani, Vahide Lajevardi, Mayade Raeiati Damavandi,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Psoriasis is a chronic papulosquamous
disorder, which affects about 2% of the population. Psoriasis is relatively
common in childhood: more than 10% of cases start before the age of 10. Tha aim
of this study was to compare the clinical characteristics between pediatric-onset
and adult-onset psoriasis in Iranian patients.
Methods: In 2006 and 2007, clinical data were collected
from all patients with psoriasis diagnosis referred to Razi Hospital. They were
categorized into two groups: pediatric-onset psoriasis patients and adult-onset
psoriasis patients. Clinical variables such as number of patients, gender, age
of onset, family history, and stress as a precipitating factor, the first site
of involvement, clinical type and involved sites were compared between the two
group.
Results: From total of 162 patients, 50 patients (33.2%)
were considered as pediatric-onset group. The percentage of males in the
pediatric-onset group was 48% compared with 58.9% in the adult-onset group. In
the pediatric-onset group positive family history was 20% and in the
adult-onset group was 12.5%. Stress as a precipitating factor was nearly the
same in both groups. Plaque type psoriasis was the most common clinical
presentation and the head and neck was the most common site of involvement in
both groups.
Conclusion: Our findings, similar to previous studies
showed that the involvement of female gender, family history and the onset of
psoriasis on the scalp in children were more than adults.
Amirhoushang Ehsan, Mahboobe Sadathosseini, Zahra Hallaji, Amirreza Hanifnia, Masoume Rohaneinasab,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Palmoplantar pustulosis is a chronic dermatosis of palms and soles, which is associated with a high recurrence rate and resistance to treatment. Various treatments with different success rates have been used.The purpose of this study was to evaluate the efficacy of local bath PUVA in the treatment of palmoplantar pustulosis.
Methods: In this retrospective study, patients with palmoplantar pustulosis who were treated with local bath PUVA in Phototherapy clinic of Razi Hospital between 2005 and 2009 were evaluated for the therapeutic efficacy of local bath PUVA. Data were analyzed using t and chi-square tests.
Results: Ninety-five patients with a mean age of 44.17 years included in this study. 49.5% of patients were males and 50.5% were females. Mean treatment cessions of patients were 42.5 sessions and mean cumulative dose was 251.8 J/cm2. In 16.8% of cases have very good response was observed. Good, moderate and poor responses were observed in 35.8%, 29.5% and 9.5% of cases, respectively. Treatment failure was observed in 8.4% of patients. Mean cumulative dose in patients with very good response was significantly higher than other response groups, (P=0.016). Mean number of treatment sessions was also significantly higher in that group with comparison with other groups, (P<0.05). Twenty percent of patients withdrawed from the study because of complications. However all complications recovered completely and no long term complications was observed.
Conclusion: This study demonstrated that local bath PUVA is an effective safe treatment for the treatment of palmoplantar pustulosis.
Zahra Hallaji, Alireza Khatami, Reza Robati, Hassan Seirafi, Alireza Firooz, Vahideh Lajevardi, Zoherh Mozafari, Parvin Mansouri, Pedram Mehryan, Mansour Nassiri-Kashani,
Volume 6, Issue 1 (Volume 6, Number 1 2015)
Abstract
Urticaria is a common and challenging skin disorder. Its diagnosis and treatment is not limited to the field of dermatology. General physicians, and allergologists and clinical immunologists are also commonly involved in the management of urticaria patients.
One of the missions of the Iranian Society of Dermatology is to develop strategies to provide the best possible management for patients suffering dermatological conditions. To accomplish this mission, the Society assigned a committee to search and critically appraise the recent research evidence and available guidelines to develop a clinical practice guideline concerning diagnosis and treatment of urticaria.
