Journal of

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Background and Aim: Pityriasis versicolor (PV) is a fungal infection of the skin that is caused by Malassezia species in tropical and subtropical areas. Various treatments such as ketoconazole 2% shampoo are effective in the treatment of PV. In this study, the therapeutic effects of ketoconazole 2% shampoo and Octopirox 1% shampoo on PV were compared. Methods: Fourty-two patients participated in the study. Twenty-five patients were treated using Octopirox 1% shampoo and 17 patients were treated by ketoconazole 2% shampoo. Each shampoo was administered for 5 minutes after daily showers for three weeks. At the end of the treatment period, patients were evaluated on the basis of the results KOH test and clinical examinations. Results: At the end of the treatment period in ketoconazole 2% shampoo group, 64.7% of patients were cured. In Octopirox 1% shampoo group, 44% of patients were cured. The detected difference was not statistically significant (P=0.187). Conclusion: Both shampoos were effective in eliminating the symptoms, but ketoconazole 2% shampoo was more effective in improving the associated hyperpigmentation and erythema than Octopirox 2% shampoo. No side effects were observed in either group.

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Background and Aim: Regarding the relatively high prevalence of depression in people with psoriasis, the present study was conducted to determine the role of type D personality and difficulties in emotion regulation in predicting the symptoms of depression in patients with psoriasis.

Methods: This study was a descriptive correlational study. Among patients referred to the Dermatology Clinic of Razi Hospital in Tehran from November to January 2016, 60 patients with psoriasis were selected using available sampling method. The research instruments included type D Personality Questionnaire (DS-14 scale), Difficulties in Emotion Regulation Scale (DERS), and Beck Depression Inventory (Second Edition) (BDI-II). Finally, the data were analyzed using Pearson correlation coefficient and multiple regression tests.

Results: The results of this study showed that there is a significant positive correlation between type D personality and difficulties in emotion regulation with symptoms of depression in patients with psoriasis (P<0/01). Regression analysis with enter method also showed that the two components of type D personality (negative affect and social inhibition), as well as two subscales (lack of emotional awareness and lack of emotional clarity) in difficulties in emotion regulation scale can predict the symptoms of depression in psoriasis.

Conclusion: Type D personality traits and difficulties in emotion regulation can affect the psychological consequences of psoriasis, including depression in people with this disease.

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Background and Aim: Oral cancer as the most common cancer of head and neck region holds the eighth rank among all cancers in order of prevalence. More than 90% of oral cancers are of squamous cell carcinoma (SCC). The main objective of this study is the determination of the survival rate in patients with oral SCC and the factors influencing thereon.

Methods: In this study, 174 recorded cases of patients with oral SCC were evaluated. Required data on survival of patients were gathered by phone calls. Using software SPSS 20, the statistical analysis of  data was carried out. The survival rate of the patients and the corresponding influential factors were analyzed by the Kaplan-Meier curves and Cox regression tests, respectively.

Results: 57.6% of the patients were male. The age of the patients ranged between 22-89 years with the average onset age of 61.5 years. The most common site of oral SCC was tongue. The overall five-year survival rate of the patients was  49.4%±0.05. The survival rate had a statistically significant relation with age of the patients and their treatment methods, including surgery or chemotherapy.

Conclusion: The prevalence of oral SCC is higher in men and overall survival rate decreases with increasing age of the patients. Due to the low survival rate of oral cancer patients, more attentions should be paid to this condition.

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Background and Aim: The aim of this study was to determine the effectiveness of psychotherapy based on improving quality of life on depression and self-esteem in women with vitiligo.
 

Methods: The present study was a quasi-experimental study (Pre-test - post-test with follow-up and control group). The statistical population of this study included all women with vitiligo skin disease referred to Isfahan Dermatology and Leishmaniasis Research Center , among which, 20 people were selected by available sampling method and randomly assigned to experimental and control groups (10 people for each group). Both groups completed Beck Depression Inventory (1996) and Rosenberg Self-Esteem (1965) Questionnaires as a pre-test and after completing eight sessions of psychotherapy based on improving quality of life (one 90-minute session per week for eight weeks), the post-test was performed again and one month later for the control and experimental groups. The collected data were analyzed using repeated measures analysis of variance in SPSS 23 software.
 

Results: Based on the findings of repeated measures analysis of variance, it was found that psychotherapy based on improving quality of life reduced the average depression scores and increased the self-esteem of women with vitiligo.
 

Conclusion: Considering that psychotherapy based on improving the quality of life has an effect on depression and self-esteem in women with vitiligo, so teaching this therapeutic approach is recommended as an effective intervention method to reduce depression and improve the self-esteem of women with vitiligo.