Showing 8 results for Koohi
Hassein Tabatabaei, Shahab Babakoohi, Makan Rahshenas,
Volume 1, Issue 1 (3-2010)
Abstract
Background and aim: Skin rejuvenation is in demand. In recent years, mono- and bipolar radiofrequency (RF) have been reckoned as treatment of choice for this purpose. The studies on RF have shown the remodeling of collagen fibers and consequently improvement of skin texture although risks and side effects may exist.
Methods: Forty-eight patients requesting skin rejuvenation were treated by RF after obtaining written consent from them. The diagnosis had been made solely on the basis of examination and observation. The photography was performed in all patients pre- and post-treatment. The pictures were evaluated by a dermatologist unaware of the sequence of photos.
Results: the wrinkles improved in 26(54%) patients. The response was better with increasing age. Transient pain and erythema were reported by all patients.
Conclusion: Radiofrequency is an appropriate treatment for reducing the number and the depth of wrinkles and needs comprehensive education. At least, 4 treatment sessions with 2-week intervals are required for effectiveness.
Zahra Delavarian, Nooshin Mohtasham, Abbas Javadzadeh Bolouri, Shahab Babakoohi, Bardia Sadr, Mohammad Taghi Shakeri, Kambiz Kamyab-Hesari, Farnaz Bidram,
Volume 1, Issue 1 (3-2010)
Abstract
Background and aim: Oral lichen planus, is a chronic inflammatory mucocutanous lesion which is defined as a premalignant lesion. Matrix metaloprotenase 2 (MMP-2) and MMP-9 are protenases which facilitates invasion of tumoral cells to connective tissue and are over-expressed in premalignant and malignant lesions. The aim of this study was to determine the expression of MMP-2 in erosive and non-erosive oral lichen planus and inflammatory hyperplasia by immunohistochemistry.
Methods: in this cross sectional study 39 specimens of non-erosive oral lichen planus (with and without dysplasia), 36 specimens of erosive ones (11 dysplastic and 25 non-dysplastic, 32 inflammatory hyperplasias and 6 samples of normal oral mucosa were chosen form pathology archive of Faculty of Dentistry, Mashhad university of Medical Sciences and were stained immunohistochemically by MMP-2 and MMP-9 markers. Kruskal-Wallis, Mann-Whitney and Spearman correlation coefficient were used.
Results: The highest mean expression of MMP-2 and MMP-9 (in all layers) were observed in erosive oral lichen planus (68.18±31.62 and 94.5±3.5, respectively). MMP-9 expression in erosive oral lichen planus in comparison to non-erosive one showed significant difference in all layers (P<0.001) and the expression of MMP-2 showed a significant difference in basal –para basal and prickle layers (respectively: P=0.008, P<0.001).
Conclusion: the linear increase seen in the expression of markers from normal mucosa to erosive oral lichen planus indicates the difference of biological behavior between erosive and non-erosive oral lichen planus. Hence, it is concluded that erosive oral lichen planus is of the higher premalignan potential compared with its non-erosive correspondent.
Bardia Sadr, Shahab Babakoohi, Ferial Fanian, Maryam Sarraf-Yazdy, Ali Kazerouni-Timsar, Mansour Nassiri-Kashani, Yahya Dowlati, Alireza Firooz,
Volume 1, Issue 2 (6-2010)
Abstract
Background and Aim: several studies have been conducted to evaluate skin pH in various diseases, but there are few reports in normal population. The aim of this study was to evaluate skin pH in healthy individuals.
Methods: Fifty healthy volunteers were enrolled in this study. The subjects were divided by age into 5 groups, i.e., 10-20, 21-30, 31-40, 41-50 and 51-60 years old. In each group, 5 females and 5 males were examined. A pH meter (Courage & Khazaka electronic GmbH, Germany) was used to measure pH in 8 different locations of the body (forehead, cheek, nasolabial fold, neck, forearm, dorsal side of hand, palm and leg).
Results: The mean values for pH in these locations were 5.25, 5.15, 5.06, 4.90, 4.75, 4.80, 4.69, and 4.83 respectively. pH was significantly higher in women (P<0.001). There was a significant difference between skin pH in different age groups (P=0.002). The highest and lowest amounts of pH belonged to the forehead (5.26 ± 0.68) and leg (4.69 ± 0.40), respectively.
Conclusion: Age and sex and location have remarkable effects on skin pH.
Mansour Nassiri-Kashani, Shahab Babakoohi, Ali Kazerouni-Timsar,
Volume 1, Issue 3 (9-2010)
Abstract
This case report introduces a 28-year-old male patient with morphea profunda, peripheral sensory motor nerve involvement, insulin dependent diabetes mellitus and hypothyroidism as an unusual presentation of deep morphea who dramatically responded to prednisolone and metothrexate after 4 months of treatment.
Mahshid Ghoncheh, Fatemeh Koohi, Hamid Salehiniya,
Volume 6, Issue 2 (Volume 6, Number 2 2015)
Abstract
Background and Aim: Skin cancer is the most common cancer in the Iran. The first step in planning for the prevention and treatment of cancers is collecting information about their incidence and trends. The present study aimed to investigate the epidemiology of skin cancer and its trend in southern Iran.
Methods: This retrospective cross-sectional study was conducted by analyzing the existing data obtained from the National Cancer Registry System in Iran. The data included all records of skin cancer cases in southern Iran. Then, the incidence rates were standardized using direct method. The data were demonstrated in frequency tables and Cochrane-Armitage test for linear trend was used for evaluation of the incidence trend.
Results: Skin cancer had a high incidence in the southern provinces of Iran. A total of 6230 cases of skin cancer during 6 years (2003-2008) were recorded in those provinces and the incidence rate of skin cancer was increasing (P=0.001). In all years of the study, skin cancer incidence was higher in males than women. In terms of frequency, Fars, Khuzestan, Bushehr and Hormozgan provinces had the highest age-standardized incidence.
Conclusion: Considering the high incidence of skin cancer and its relationship to sun exposure, educating people on the correct sun protection, educating and empowering physicians and the people about early detection of skin cancers seems to be important in preventing its increasing trend.
Amirhoushang Ehsani, Pedram Nourmohammadpour, Kambiz Kamyab Hesari, Seyedmohammad Bahrainian, Mina Koohian Mohammadabadi, Ala Ehsani, Amirhossein Rahimnia,
Volume 13, Issue 4 (Volume 13, No 4 2023)
Abstract
Background and Aim: One of the most important pathologies of tattooing is granulomatous reaction to the tattoo which is usually represented by symptoms like pain, inflation, redness and tenderness at the tattoo area. Granulomatous reaction to tattoo occurs at all ages and has been seen among both male and female. Due to the new rise in popularity of cosmetic tattoos and its pathologies, we intend to explore a descriptive study of the demographic and histopathologic characteristics of the granulomatous reactions due to cosmetic tattoos.
Methods: Razi hospital patients with proven tattoo granuloma pathology in a 3-year period were identified and studied and their demographic-histological characteristics were recorded. The study is of a cross-sectional type. 196 patients were enrolled in the study, a questionnaire was prepared for each patient and information was collected through them.
Results: The mean ± standard deviation age of the patients was 45.46±8.54. The mean ± standard deviation tattoo time was 4.18±4.33. The mean ± standard deviation frequency of tattooing was 1.64±1.8. The most common tattoo area was eyebrow in 88.3% of the patients and least common was upper eyelid in 0.6%. The most common pathology result was tattoo granuloma in 41.7% of the patients and the least common was Lichenoid in 2.8%.
Conclusion: Considering the highest frequency of pathological diagnosis of tattoo-granuloma (Sarcoidal and foreign body) with 41.7% in our study and observing the relationship between tattoo-granuloma and sarcoidosis in previous studies, complete examination of patients, long-term follow-up of patients which will have sarcoidosis in the future and examining the clinical response to treatment seems logical and beneficial. It is also important to consider whether the treatment of current lesions will play a role in preventing sarcoidosis in the future or not.
Amirhoushang Ehsani, Hasan Hajmohammadtaghiseyrafi, Pedram Nourmohammadpour, Mahdi Naghdipour, Mina Koohian Mohammadabadi, Ala Ehsani, Amirhossein Rahimnia,
Volume 14, Issue 1 (Volume 14, No 1 2023)
Abstract
Background and Aim: Lower limb telangiectasias are commonly seen in the general population and especially in females. This disorder not only causes cosmetic problems but also can cause pain and related problems of increased venous blood pressure. These varicose veins are one of the most common causes that patients refer to dermatology clinics. Considering some complications and limitations of sclerotherapy, we decided to investigate the efficacy and safety of the Long-Pulsed Nd:YAG 1064-nm laser as an alternative method.
Methods: 29 patients underwent at least three sessions of 1064 nm Nd: YAG laser treatment at intervals of 4 weeks. Before the first treatment session, after each session, and six months after the last session, photos were taken of the treatment site. Finally, clinical response and satisfaction rate with the treatment were recorded based on the score of a secondary dermatologist and the patient himself based on the improvement criteria from 0 to 4.
Results: According to the dermatologist's judgment, the average satisfaction with the treatment is 3.38 out of 4 with a standard deviation of 0.5, and based on the patient's assessment, it is 3.2 out of 4 with a standard deviation of 0.71, which is equivalent to more than 76% of the effectiveness of Nd:YAG 1064 nm laser in the treatment of telangiectatic veins. The pain during laser treatment was recorded as 6.27 with a standard deviation of 2.64 based on The VAS Scale.
Conclusion: Our experience has demonstrated that the long-pulsed 1064 nm Nd:YAG laser is an effective, reliable, safe method in the treatment of telangiectatic and reticular veins of the lower limbs with minimal side effects and complications.
Ala Ehsani, Amirhoushang Ehsani, Zahra Razavi, Mina Koohian Mohammadabadi, Mahshidsadat Ansari, Zeynab Aryanian, Pedram Nourmohammadpour, Amirmohammad Almasi, Amirhossein Rahimnia,
Volume 15, Issue 2 (Volume 15, No 2 2024)
Abstract
Background and aim: As the use of botulinum toxin to treat glabellar lines increases, particularly in Iran, where foreign products (e.g. Dysport) are relatively expensive, it becomes important to compare the efficacy, side effects, and duration of action of two locally produced botulinum toxin brands, Masport® and Dyston®. This study seeks to assess and compare the treatment results of these two medications.
Methods: In this cross-sectional, descriptive, retrospective study, the medical records of 81 patients who visited Razi Dermatology Hospital for the treatment of moderate to severe glabellar lines were reviewed. Data related to patient satisfaction, duration of action, and side effects of Masport® and Dyston® botulinum toxin were collected and analyzed via a questionnaire.
Results: The mean satisfaction score was 7 for the Dyston® group and 7.7 for the Masport® group, with no statistically significant difference between the two groups (P=0.142). Additionally, the mean duration of action was 3.5 months for Dyston® and 3.8 months for Masport®, with no significant difference observed. Headache was the most common side effect reported, with no other major adverse events noted. Furthermore, there was no statistically significant difference in the incidence of side effects between the two groups.
Conclusion: The findings of this study indicate that both Dyston® and Masport® have similar efficacy and safety profiles. The choice between them can be primarily based on cost and patient or physician preference rather than any significant therapeutic differences. Larger studies are recommended to further validate these findings.
