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Monireh Ensaf, Masoome Khanahmadi, Shahla Mirzaee,
Volume 9, Issue 1 (2018, Volume 9, Number 1 2018)
Abstract

Background and Aim: Shampoos are products that remove fat and dust from the hair and scalp. Cleansing and decontamination are the most important properties of a shampoo for its acceptance. To create a stable foam in shampoos, alkaloids are often used which are believed to be carcinogens due to production of nitrosamines. Hence, the main goal of this study was the production of shampoo by using medicinal plants.

Methods: In this study, herbal shampoos were prepared by using aqueous and hydro-alcoholic extracts of Yarrow, Cedar, Chubak and licorice as surfactants, and Katira as thickener. Then their physical and chemical properties were analyzed.

Results: After preparing the herbal base shampoo, the physical and chemical evaluation of the product was performed. We found that this formulation had cleansing power for foam formation, antimicrobial and antifungal properties, and also a high shelf life compared to the control sample (chemical shampoo). It also didn’t have any adverse effect on hair and scalp of consumers. The present formulation is also suitable for commercial shampoo production.

Conclusion: The herbal based shampoo had better qualitative properties than the chemical base, and the use of the aqueous extract of the aforementioned plants (compared to their hydro alcoholic extracts) had better performance and was economically feasible.
Saba Mehrandish, Shahla Mirzaee,
Volume 9, Issue 4 (2018, Volume 9, Number 4 2019)
Abstract

Fungi are eukaryotic organisms that potentially have the ability to cause disease in humans and animals. Fungal infections are called mycosis, which are divided into four types of superficial, cutaneous, subcutaneous and systemic, depending on the area of ​​the body involved. Though cutaneous mycoses are rarely life-threatening infections, they can isolate the patient socially due to the disfigurement of the tissues they caused, as a result of which, treatment has always been an important issue. On the other hand the similarity of fungi to mammalian cells led to difficulties in the development of novel antifungal drugs. Consequently, in recent years, extensive efforts have been made to design and develop novel drug delivery systems with better efficacy for drug delivery of conventional anti-fungal drugs. In this study, we compared conventional forms and novel drug delivery systems of a number of antifungal drugs. All studies confirm the relative priority of novel drug delivery systems to conventional forms in terms of penetration, release, and antifungal effects.

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