Journal of

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Background and Aim: Mobile-based applications have the potential to increase the awareness of skin patients to their disease. The main goal is to rise clients' information about their skin disease, skin cell therapy and to provide Rooyan’s Center informations, specialists list, addresses, presentations, clips and relevant photos of the disease.

Methods: To identify the information, a researcher-made questionnaire was used. The questionnaires were validated by experts. Information system software was designed and developed using Joapp's Windows software. Finally, it was evaluated using a standard questionnaire assessing user satisfaction and program usability.

Results: Users evaluation in four axes: software performance with average (81.3%), Software display with average (78.9%), Software terminology and information with average (68.1%), the overall software capability (82.8%) and the overall mean score of 77.7% were rated as "good".

Conclusion: Treatment of this disease is necessary and important due to mental stress. Due to the inefficiency of existing treatments, complementary therapies to control the disease are on the rise. The software gives patients a broader view of their disease and has been very useful and effcient.

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Microneedles are micron structures that provide the possibility of drug delivery, vaccination and sampling of different organs. The use of microneedles does not require special skills and training, it significantly reduces the dosage and allows the timely release of the drug. The numerous advantages of microneedles compared to other methods of drug delivery have attracted the attention of many researchers. Microneedles are made from the order of microns to millimeters using microfabrication technology using various metals, silicon and polymers. So far, various methods have been proposed for making microneedles. In this article, the conventional and widely used methods of microneedle manufacturing are presented along with their advantages and limitations in terms of the effective parameters in the selection of microneedle. Effective factors such as the type of drug, the desired mechanism for drug delivery, the dimensions and material type lead to the selection of different methods for making microneedles. Among the existing micro fabrication methods, the casting method has the ability to produce different types of microneedles, and thus has been the most popular. The casting method is simple and cheap and can be produced in high volume. Deep reactive ion etching methods make high-precision microneedles, but due to the need for advanced and expensive equipment, a skilled person, and a complex and time-consuming process, they are not capable of mass production. Meanwhile, 3D printing with fully automatic processes is a good option to choose.