Showing 29 results for Mohammadi
Soheila Mohammadi, Mohammad Hossein Baghiani Moghadam, Mohammad Taghi Noorbala, Seyed Saeed Mazloomi, Hossein Fallahzadeh, Ali Daya,
Volume 1, Issue 2 (6-2010)
Abstract
Backgound and Aim: Skin cancer is the most prevalent type of cancer in Yazd city. Childhood and adolescense is an important time for preventing the skin cancers. The aim of this study was to survey the role of appearance concern with skin cancer prevention behavior based on protection motivation theory.
Methods: Participants in this cross- sectional study were 360 female students from 4 high schools in Yazd city. Data were gathered by using self-reporting questionnaires and were analyzed using SPSS software applying ANOVA, Pearson's correlation coefficient and linear regression tests.
Results: Using Pearson's correlation test, a statistically significant correlation between the appearance concern with perceived susceptibility, perceived severity, self-efficacy, response efficacy, protection motivation and behaviors was found (P<0.01). The perceived susceptibility, perceived severity, self- efficacy, response efficacy, protection motivation, response costs and appearance concern could predict 0.56 of the behaviors and perceived susceptibility was the strongest predictor (β=0.120). Also, protection motivation could predict behavior (41 %).
Conclusion: Results of this study support the effectiveness of protection motivation theory variables and the role of appearance concern for prediction of skin cancer prevention behaviors in participants.
Ali Khamesipour, Mahmoud Nateghi Rostami, Hossein Keshavarz, Akram Miramin Mohammadi, Minoo Tasbihi, Seyyedeh Tahereh Shahrestani, Abdolfattah Sarrafnejad,
Volume 1, Issue 3 (9-2010)
Abstract
Background and Aim: The heterogenous population of memory T lymphocytes is distinguished based on surface markers and effector functions such as cytokine secretion. Recently, two subsets of memory T cells are defined by expression of chemokine receptor CCR7 and CD45RA designating as "central memory" T cells (TCM) and "effector memory" T cells (TEM). The objective of this staudy was to evaluate the phenotype and function of these lymphocytes in healed cases of cutaneous leishmaniasis.
Methods: The phenotype of lymphocytes were determined in blood samples of 13 volunteers with history of self healing cutaneous leishmaniasis (HCL) and in 6 healthy controls.
Results: No significant difference was found in memory T cell subsets between HCL volunteers and healthy controls using flow cytometry. However, following sorting of different memory subsets, a significantly higher proliferation was seen in cells of HCL volunteers comparing to the control group. A significantly higher IFN-γ response in TEM and a significantly higher IL-2 response in TCM were observed in cell culture of HCL volunteers comparing controls.
Conclusion: The responses were elicited when the cells were stimulate with SLA in vitro, it is concluded Leishmania-specific TEM and Leishmania-specific TCM subsets exist in HCL volunteers and since the volunteers with history of CL presumed to be protected against reinfection, it seems that both TCM and TEM play role in the protection against Leishmania infection in these individuals.
Shahram Baghestani, Shahram Zare, Foroogh Mohammadi, Keramat-O-Allah Jahanshahi,
Volume 1, Issue 4 (12-2010)
Abstract
Background and Aim: Chronic renal failure is a clinical state which results in declining the kidney function. Chronic renal failure has numerous cutaneous manifestations, when the process of hemodialysis begins, new changes may appear as a result. The aim of this study was to assess the prevalence of cutaneous problems among patients with chronic renal failure undergoing hemodialysis in Bandar Abbas, Iran.
Methods: In this cross-sectional study, 60 patients with chronic renal failure under hemodialysis in Shahid Mohammadi Hospital Dialysis Center were examined by a dermatologist. The data were gathered and analyzed by SPSS software (version 16) using descriptive statistics, t and chi2 tests. P less than 0.05 was considered significant.
Results: The most common skin findings were dry skin (78.3%), followed by pallor (71.7%) and pruritus (58.3%). Other common cutaneous manifestations were half-half nail (35%), idiopathic guttate hypomelanosis (33.3%), yellowish skin color change (31.7%), subungal hyperkeratosis (30%), onycholysis (20%), beau's line (15%), cherry angioma (15%), skin hyperpigmentation (15%) and purpura (13.3%).
Conclusion: Chronic renal failure is associated with various cutaneous manifestations caused by hemodiaysis or the disease itself. The most common ones are dry skin and pallor. The early diagnosis of cutaneous changes may decrease the morbidity and eventually lead to quality of life improvement in these patients.
Afshar Ramezanpour, Abdolamir Feizi, Ramin Mohammadi,
Volume 2, Issue 1 (3-2011)
Abstract
Fabry disease is a X-linked lysosomal storage disorder due to alpha galactosidase A deficiency leading to abnormal accumulation of glycosphingolipids in different parts of body. This case report introduces a 35-year-old man with diffuse keratotic erythematous papules. Histopathological evaluation of the skin biopsy suggested the diagnosis of angiokeratoma. With attention to his nephropathy and the same skin lesions and renal involvement in his brother, which led him to receive renal transplantation, the diagnosis of Fabry disease was suggested.
Mahnaz Mahmoudi Rad, Akram Miramin Mohammadi, Parviz Tousi, Ali Khamesipour, Amirhoushang Ehsani, Seyyed Ebrahim Eskandari, Niki Mahmoudi Rad, Yasaman Mirdamadi, Zeinab Ghasemi, Mohsen Gerami Shoar, Shima Younespour,
Volume 2, Issue 2 (6-2011)
Abstract
Background and Aim: Malassezia is a lipophilic and dimorphic fungus which has different species. Some of them can be found as natural flora on skin and in some conditions may cause pityriasis versicolor. The aim of this study was to identify Malassezia species associated with pityriasis versicolor in Iranian patients, using PCR-RFLP.
Methods: In this study out of 65 patients with pityriasis versicolor to have pityriasis versicolor,isolates of 60 patients were positive. Malassezia species. using by PCR-RFLP. The Internal Transcribed Spacer 2 (ITS2) region was amplified by PCR employing the ITS3 and ITS4 primers and The restriction endonucleases AluI, BanI and MspAI were selected for producing distinct RFLP patterns.
Results: M. furfur (36.7%), M. globosa (30.0%), M. sympodialis (20.0%), M. slooffiae (8.3%), M. restricta (3.3%) and M. obtusa (1.7%) were the microorganisms responsible for the infection among participants. The M. sympodialis infection was strongly correlated with the female gender (P=0.02).
Conclusion: Our findings suggest that, the most common Malassezia species associated with pityriasis versicolor was M. furfur, followed by M. globosa.
Mahnaz Mahmoudi Rad, Akram Miramin Mohammadi, Parviz Tousi, Alireza Firooz, Seyyed Ebrahim Eskandari, Niki Mahmoudi Rad, Yasaman Mirdamadi, Amirhoushang Ehsani, Zeinab Ghasemi, Shima Younespour,
Volume 2, Issue 2 (6-2011)
Abstract
Background and Aim: Malassezia is a lipophilic and dimorphic fungus which has different species. Some of them can be found as natural flora on the skin and in some conditions may cause seborrheic dermatitis. The aim of this study was to identify Malassezia species associated with seborrheic dermatitis in Iranian patients, using PCR-RFLP.
Methods: In this study out of 79 patients with seborrheic dermatitis, isolates of 70 patients were positive for Malassezia species using PCR-RFLP. The Internal Transcribed Spacer 2 (ITS2) region was amplified by PCR employing the ITS3 and ITS4 primers and The restriction endonucleases AluI, BanI and MspAI were selected for producing distinct RFLP patterns.
Results: M. globosa (48.6%), M. furfur (40.0%), M. slooffiae (8.6%) and M. sympodialis (2.8%), were the microorganisms responsible for the infection among participants. M. pachydermatis, M. japonica, M. dermatis, M. restricta, M. obtuse, M. nana and M. yamatoensis were not isolated from any samples.
Conclusion: Our findings suggest that the most common Malassezia species associated with seborrheic dermatitis was M. globosa, followed by M. furfur.
Mona Malekmohammadi, Hossein Abdol Tehrani, Nasser Aghdami,
Volume 2, Issue 3 (9-2011)
Abstract
Hyaluronic acid (HA), the main and most important constituent of extracellular matrix, is a glycosaminologycan with water-absorbing capacity found in large amount in growing and repairing tissues. One of the main causes of skin problems, particulary in aging skin, is HA deficiency. More than half of the body HA is in the skin and is necessary for the maintenance of internal matrix and several cellular functions. Filler gels containing HA are used to repair skin defects. As these substances are derived from animals and bacteria, not the human, may cause skin reactions and have short half-life. So efforts to maintain and/or increase HA secretion from skin fibroblasts are important in the prevention and treatment of skin aging.
Mona Malekmohammadi, Hossein Abdol Tehrani, Nasser Aghdami,
Volume 2, Issue 4 (12-2011)
Abstract
Skin injury caused by burns, surgery and other traumas may result in unpleasant psychological experiences and be reflected in behaviors. Extracellular matrix (ECM) is the largest component of natural skin which is gel-like and is produced by skin cells. ECM synthesis is a key factor for filling up skin wounds such as burns, leishmaniasis, chicken pox, acne, etc. ECM is composed of a variety of polysaccharides, water, and collagen proteins. Considering its weight, natural skin strength and its expandability are like steel, while it has high elasticity and compaction capacities. These characteristics are due to dual effects of main ECM molecules, which are secreted by fibroblasts and epidermal cells: 1) structural fiber proteins like: elastin, fibronectin and laminin which give strength and flexibility to ECM, and 2) proteoglycans such as dermatan sulfate and hyaluronic acid which are consisted of few glycosaminoglycan chains that branch out from a linear protein core. Proteoglycans are large and hydrated molecules which are resistant to external forces and protect underneath cells. In general, understanding the skin structure and wound healing phases can help us to design useful experiments and to conduct proper researches in this area.
Mona Malekmohammadi, Hossein A. Tehrani, Nasser Aghdami,
Volume 3, Issue 1 (3-2012)
Abstract
Background and Aim: Synthesis of extracellular matrix (ECM) is a key factor in wound healing. The predominant component of ECM is hyaluronic acid (HA). Recent studies have shown that adipose derived stem cell-conditioned medium (ADSC-CM) can increase the expression and synthesis of collagen I, III and fibronectin which are the components of ECM. The purpose of this study was to investigate the effects of ADSC-CM on the expression of HA synthase and degrading genes in human dermal fibroblasts (HDF).Methods: ADSCs were isolated from three liposuction samples and their conditioned medium was collected. Skin biopsies were isolated from six patients and their fibroblasts were isolated. These cells were cultured in 100% of ADSC-CM. Expression of three HA synthase and two hyaluronidase genes were assessed with the use of real time PCR, with ELISA and final amounts of secreted HA were measured in the treated and control groups.
Results: Gene expression of two HA synthase genes HAS1 and HAS2 were upregulated in treated samples compared to the control group. The expression of one hyaluronidase gene, HYAL2, was downregulated in them. Final amount of HA was increased in the treated samples.
Conclusion: The expression and synthesis of HA can be increased by the stimulatory effect of growth factors present in ADSC-CM. Thus, secretomes of ADSCs could play a crucial role in wound healing by up-regulating the production of ECM’s components in HDFs.
Farzaneh Zarrinkar, Ali Khamesipour, Akram Miraminmohammadi, Ebrahim Eskandari, Mahmoud Nateghi Rostami, Esmaeil Fallah,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Leishmanization (LZ) is an effective tool to prevent
cutaneous leishmaniasis. Standardization of Leishmania is
the main drawback of LZ. The aim of this study was to assess the effect of
various preservatives on the infectivity of Leishmania.Methods: L.major harvested
at different stages of growth logarithmic, early and late stationary phases
were frozen using various preservatives of saccharose, glycerol, trehalose,
glucose, sorbitol, and dimethyl sulfoxide (DMSO). The harvested parasites were
inoculated into BALB/c mice before and after freezing. The infectivity of the
parasites was checked. IFA test was used to assess the rate of metacyclic
parasite.
Results: The ratio of
live Leishmania in different growth stages and various
preservatives were 89.0% to 98.2%. The lesion development in groups of mice
which received Leishmania in sacarose + glycerol or DMSO was started from 3rd
week and at 5th week all the mice showed lesion. The group of mice
which were inoculated with early or late stationary phases in saccharose +
glucose, saccharose + glycerol, glycerol 15% or DMSO showed lesion from 4th
to 5th week and in 100% showed lesions at 8th week. The
rate of metacyclic parasites increases from log phase to early and late
stationary phases.
Conclusion: There was a
correlation between percent of live parasite and the rate of lesion development
in BALB/c mice. Saccharose 22.5% + Glyserol 22.5% were the most appropriate preservative to freeze L. major. IFA
test is used to detect metacyclic Leishmania. A correlation was seen between the rate of
lesion development in BALB/c mice and IFA positivity.
Pedram Noormohammadpour, Amirhooshang Ehsani, Mostafa Mirshams Shashahani, Fatemeh Shahmohammadi, Fatemeh Gholamali,
Volume 5, Issue 1 (Volume 5, Number 1 2014)
Abstract
Background and Aim: Malignant melanoma is one of the most lethal skin tumors. Its prevalence and demographic specifications are different in European and western countries from those in the Middle East. This study was aimed to evaluate the demographic and clinical characteristics of malignant melanoma in Iran.
Methods: In this cross-sectional study, the patients with the diagnosis of malignant melanoma who atteneded the tumor clinic of Razi Hospital, Tehran, Iran were included. Demographic and clinical data were registered in specific questionnaires. Histopathology findings were also recorded in the questionnaires.
Results: A total of 2500 patients attending tumor clinic of Razi Hospital were evaluated. Out of them, 166 cases had malignant melanoma including 89 (53.6%) females and 77 males (46.4%). The mean age of patients 60.5 years. History of chronic sun exposure was found in 65 (39.2%) cases. Mean delay time between commencement of lesion and diagnosis was 9 months. The most common histopathologic type was acral lentiginous and the most common observed stage of tumor was Clark 3. The most common frequent observed tumor site was head and neck which was followed by limbs.
Conclusion: Malignant melanoma is common in patients with skin tumors in Iran. Considering morbidity and mortality of malignant melanoma and the relatively high stages of tumors, at the fist time the patients sought medical care, screening programs seems to be necessary to find the patients in earlier stages, as well as the mass education. Some of our findings such as the most common location of the tumors, family history and relation with dysplastic naevies, remain to be confirmed in studies with larger sample sizes.
Maryam Mirzaei, Saeid Razi, Mahshid Ghoncheh, Abdollah Mohammadian Hafshejani, Hamid Salehiniya,
Volume 5, Issue 4 (Volume 5, Number 4 2015)
Abstract
|
Background and Aim: Skin
cancer is the most common cancer in the world, which is associated with
mortality, mortality and health care costs. Planning prevention and control
of this cancer, information about its incidence rates and incidence trends is
necessary. The present study aimed to determine the incidence rates and
trends of skin cancer in Tehran.
Methods: In this
cross-sectional study, necessary data were extracted from the Cancer
Registry, Ministry of Health and Medical Education between 2003 and 2008. Age
- and sex -standardized incidence rates were calculated and the incidence
rate trends were determined.
Results: Between 2003 and
2008, 7429 skin cancer cases were recorded, of which 4807 were men and 2622
were women. Skin cancer incidence had an increasing trend in Tehran and its
incidence rate has increased from 8.99 in women and 11.52 in men in 2003 to
18.03 in women and 28.16 in men in 2008, respectively. In addition, incidence
of skin cancer was increased with aging in both men and women. The incidence
rate was higher in men than women.
Conclusion: Skin cancer
incidence in Tehran is increasing, which could be due to population aging,
environmental risk factors, and changes in life style. More comprehensive
research is suggested to investigate the risk factors for this cancer in
Tehran.
|
Mohammad Saatchi, Hamid Salehinia, Salman Khazaei, Mahdi Mohammadian, Abdollah Mohammadian-Hafshejani,
Volume 6, Issue 2 (Volume 6, Number 2 2015)
Abstract
Background and Aim: The aim of this study was to investigate various aspects of the treatment in patients with cutaneous leishmaniasis in Iran in the first half of 2014.
Methods: This cross sectional study was conducted on the existing data of 3684 patients with cutaneous leishmaniasis, whom were registered at the Disease Management Center of the Iranian Ministry of Health in the first half of 2014. Version 11 of Stata was used for statistical analysis and the level of significance was considered equals to 0.05.
Results: Of 3684 patients entered into the study (%55.1) were male and the mean age of the patients was 27±18 years. More than 34% of patients were treated with intralesional injections of meglumine antimoniate (MA) and 25% of patients recieved systemic MA injections. There were statistically significant correlations between the size and number of the lesions and the chosen treatment regimen (P<0.001). Thirty-five percent of patients treated with systemic MA between 7 to 10 days and 43.3% of patients recieved intralesional MA injections for 5 to 8 weeks.
Conclusion: More than %99 of patients fully recovered without complication or treatment failure. It seems that Iranian patients suffered milder CL in comparison with some other coutries.
Saman Mohammadi, Payam Khazaeli, Simin Shamsi Meymandi, Mahin Aflatoonian, Maryam Khalili Meybodi, Niloofar Mehrolhasani, Azadeh Mohebi, Yuns Jahani,
Volume 7, Issue 2 (Volume 7, Number 2 2016)
Abstract
Background and Aim: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. Retinoids are used as the first line therapy in acne. Systemic absorption and skin irritation including redness, pruritus and exfoliation are some of their side effects. In this study we compared the efficacy of isotretinoin 0.05% niosomal gel versus adapalen 0.1% gel in treatment of acne vulgaris.
Methods: In this randomized double blind clinical trial, 144 patients with mild to moderate acne vulgaris aged from 15 to 30 years were enrolled. The patients were randomly allocated into two groups of A, whom were treated with isotretinoin 0.05% niosomal gel and B whom were treated with adapalen 0.1% gel. The patients were evaluated for clinical reponse, decrease in the number of inflammatory and non-inflammatory lesions and side effects after 2, 4, 8, and 12 weeks of the initiation of treatment.
Results: At the end of the study the clinical responses of comedones and inflammatory lesions in isotretinoin 0.05% niosomal gel group were 68% and 79%, in comparison with 65% and 76% in the adapalen gel group, respectively. The differences were not statistically significant. At the end of the treatment period more decrease in number of inflammatory and non-inflammatory lesions were seen in group A patients (niosomal isotretinoin) than group B (adapalen 0.1% gel) (P<0.001). Also side effect of skin redness was found more in group B (P<0.001).
Conclusion: Isotretinoin 0.05% niosomal gel has less side effects and more efficacy in the treatment of mild to moderate acne vulgaris in comparison with adapalen 0.1% gel.
Mehraban Felahati, Zeinab Ghasemi, Safar Shamohammadi, Seyed Ebrahim Eskandari, Reza Amiri, Mahdieh Rahimi, Dastparvardeh Elmira, Shahabeddin Rahimifar,
Volume 7, Issue 3 (Volume 7, Number 3 2016)
Abstract
Background and Aim: Bacteria are one of the causes of nail infections. Although nail infections are not always associated with a major health problem, their treatment, particularly in immunosuppressed patients could be chalenging. This study was conducted to investigate the prevalence of bacterial agents in patients with dystrophic nails referred to mycology laboratory of Razi Hospital, Tehran.
Methods: This was a cross-sectional study on patients with dystrophic nail. Samples were examined by both direct examination and culture. Blood agar and eosin methylene blue (EMB) agar media were used to culture and differentiate bacteria.
Results: Of 700 dystrophic nail samples, 183 (26.1%) samples were diagnosed as onychomycosis. One hundred and four (56.8%) of the patients were female. One hundred and eighty-one patients had bacterial nail infection (25.9%), of whom 109 (60.2%) were female. Forty-six (6.6%) patients had both bacterial and fungul infections, of whom 32 (69.6%) were female. The most common detected agent was Staphylococci.
Conclusion: Bacterial infections can result in dystrophioc nails. If these infections remain untreated they can lead to nail loss. In most cases, treatment of bacterial nail infections is easier than fungul nail infections.
Yousof Fakour, Amir Houshang Ehsani, Saeedeh Mohammadi,
Volume 7, Issue 3 (Volume 7, Number 3 2016)
Abstract
Background and Aim: Psoriasis is a common chronic skin disease with high morbidity and economic burden for patients and healthcare system. The goal of this study was to evaluate the impact of age, disease severity, and therapeutic regimen on the quality of life of the patients with psoriasis who were treated with biological drugs.
Methods: This cross-sectional study was conducted on 110 patients suffering from psoriasis whom were admitted to the psoriasis clinic in Razi Hospital, Tehran, Iran in 2015 and 2016. The Persian version of the Dermatology Life Quality Index (DLQI) questionnaire was used to evaluate patients' quality of lives. Using IBM SPSS Statistics (IBM Corp., Armonk, NY, USA) version 22, descriptive and inferential statistics methods were applied to summarize and present the collected data. Chi square test was used for making comparisons.
Results: Seventy-four male patients and 36 female patients were enrolled. The mean age of the participants was 38.8 (range: 18 to 73) years. DLQI scores had a normal distribution and a mean ± standard deviation (SD) equals to 6.51±6.66. The correlations between age and disease severity, quality of life and age, as well as quality of life and disease severity, and quality of life and treatment were not significant (P>0.05).
Conclusion: It seems that the quality of lives of the patients were not affected by the age, severity of the disease, and therapeutic regimen of biological drugs.
Fahime Nemati, Masome Mohammadzaki, Safar Shamohammadi, Zeinab Ghassemi, Ebrahim Eskandari,
Volume 8, Issue 1 (Volume 8, Number 1 2017)
Abstract
Background and Aim: Staphylococcus aureus is the second cause of hospital acquired infections, and responsible for 80% of purulent infections, and majority of skin infections. About 30 to 50 percent of normal people carry staph in their nose or groin and armpits. VanA, VanB, VanC1, VanC2/C3, VanG, VanL, and VanX are genes responsible for encoding resistance to vancomycin, TychoPlanyn and Avoparcyn, among them vanBand vanAare the most common cause of resistance that could be located on a plasmid or a chromosome and can be transferred via conjugation. The aim of this study was to The aim of this study was to investigatethe role of VanA and VanB genes in Cefoxitin resistant Staphylococci aureuscausing skin infections in patients admitted to Razi Hospital in Tehran using real time PCR method.
Methods: The samples were collected from Khordad 1394 for one year in the Microbiology Department of the Clinical Laboratory of Razi Hospital. Exudative skin lesions were sampled by sterile swab and cultured on the blood agar and EMB medium. Then catalase, oxidase and coagulase tests were performed on the gram-positive cocci and the sensitivity to vancomycinin Cefoxitin-resistant Staphylococcus aureus was determined using the E-test method. The presence of vanAand vanBgenes were investigated by Real Time PCR.
Results: Out of 978 patients with infected skin lesions, 733 samples of Staphylococcus aureus were isolated. Of these, 124 were Cefoxitin resistant, among them 8 samples had a high response rate of 3, and 5had high response above 16. But VanA and VanB genes were not responsible for resistance in any of them.
Conclusion: Due to the development of resistant strains of Staphylococcus in skin and hospital infections, identification of its encoding genes are necessary in order to use appropriate antibiotics to reduce the course of treatment and the side effects of taking antibiotics.
Masoud Mohammadi,
Volume 8, Issue 3 (Volume 8, Number 3 2017)
Abstract
Background and Aim: Alopecia is one of the most common chronic skin diseases and is one of the most important predictors of psychological distress and depression. Considering the importance of this issue to public health, this study evaluated the impact of alopecia on increasing depression in the affected population
Methods: A meta-analysis was performed for relevant articles in scientific databases including SID, Science direct and PubMed (Medline). Reference lists of identified articles were reviewed for additional articles. Heterogeneity of study was checked using I2 index. Data were analyzed using the Comprehensive Meta-analysis (CMA) software.
Results: The overall prevalence of depression in patients with alopecia in Iran was %60.3 (%95 Cl %51.4-%68.5) during 2001-2015. The highest prevalence of depression was recorded in Khorramabad in 2007, %66.7 (%95 Cl: %56.3-%75.6) and the lowest prevalence of depression was found in Mashhad in 2010, %47.3 (%95 Cl: %41.7-%53).
Conclusion: According to the results of this study, the prevalence of depression in patients with alopecia is high and therefore appropriate therapies and the need for psychological counseling for these patients seems to be necessary.
Hamid Kharatzadeh, Abolfazl Mohammadi, Fariba Jaffary, Sayed Mohsen Hoseini,
Volume 9, Issue 2 (2018, Volume 9, Number 2 2018)
Abstract
Background and Aim: Vitiligo is a prevalent depigmentaling skin disorder, which has a great impact on the quality of life of patients. The purpose of this study was to investigate the relationship of quality of life of these patients with self-compassion and experiential avoidance.
Methods: In this analytical cross-sectional study, Self-Compassion Scale (SCS), Second Edition of Acceptance and Action Questionnaire (AAQ-II), and Vitiligo Quality of Life Index (VitiQoL) were completed by 105 patients with vitiligo (49.5% male) who were selected through available sampling method. The data were analyzed using descriptive statistics, Pearson correlation coefficient, t-test, ANOVA and covariance analysis.
Results: The average of quality of life score of the participants in the study was 32.14. There was a significant relationship (P<0.01) of the quality of life scores with the scores of experiential avoidance (R=0.28), self-judgment (R=0.36), isolation (R=0.52) and extreme identification (R=0.42). After removing the confounding effect of the variables on each other, the relationship of quality of life score with the location of the lesion (P=0.04) and isolation score (P=0.001) was significant.
Conclusion: Self-compassion and experiential avoidance play an important role in the quality of life of patients with vitiligo, and targeting these two components through psychological treatments can be effective in improving the quality of life of these patients.
Parviz Molavi, Majid Rostami, Mehriar Nadermohammadi Moghadam, Atrin Khalkhali, Habibeh Salvat,
Volume 9, Issue 3 (2018, Volume 9, Number 3 2018)
Abstract
Background and Aim: Considering the high role of psychological factors in somatic disorders, especially in dermatologic disorders, the prevalence of personality disorders in psoriatic patients was studied.
Methods: Among patients referred to Dermatology Clinic of Imam Khomeini Hospital in Ardabil, 81 patients with psoriasis (case group) and 80 without skin disease (control group) were evaluated. The two groups were matched in terms of age and sex. The severity of psoriasis was determined based on the psoriasis area and severity index (PASI) index as mild, moderate and severe by the dermatologist. The traits and personality disorders were assessed and compared between two groups using MCMI-III questionnaire.
Results: There was a significant difference in depressive, dependent, obsessive and hystrionic personality traits or disorders between two groups. There was a reverse correlation between the severity were more common psoriasis and obsessive and dependent personality disorders, so they among mild and moderate psoriasis patients.
Conclusion: This study emphasized the role of psychological factors in course of psoriasis. Better strategies for prevention and treatment of psoriasis will be achieved by a careful examination of the behavioral, cognitive and emotional patterns of cluster C personality. It is also necessary to provide psychotherapy services to these patients along with drug therapy.
