Showing 2 results for Mohiti Asli
Saman Ahmad Nasrollahi, Hurnaz Hassanzade, Taraneh Yazdanparast, Shadi Marami Zenouz, Mehdi Mohiti Asli, Alireza Firooz,
Volume 5, Issue 2 (Volume 5, Number 2 2014)
Abstract
Background and Aim: Sunscreens are an important part of photoprotection strategy. They are exposed to strict safety evaluation using human subjects such as in vivo studies of skin irritation. Biophysical parameters measurements could be used as fast and noninvasive methods to measure any destructive effect of cosmetic formulations on skin application sites.
Methods: Five sunscreens were selected from Iran's market to determine changes in Transepidermal Water Loss (TEWL), stratum corneum hydration, pH, melanin and hemoglobin contents by biometric assessments with MPA 580Cutometer®.
Results: There was no significant change in skin pH, melanin and hemoglobin contents before and after sunscreen application. Significant change in TEWL and stratum corneum hydration after use of some sunscreens might be contributed by the occlusive and humectant ingredients which used in base cream.
Conclusion: Application of the studied sunscreens on human volunteers has not shown any adverse effects and these formulations could be recommended to use.
Saman Ahmad Nasrollahi, Hurnaz Hassanzade, Taraneh Yazdanparast, Somayeh Yadangi, Shadi Marami Zonouz, Mehdi Mohiti Asli, Alireza Firooz,
Volume 5, Issue 3 (Volume 5, Number 3 2014)
Abstract
Background and Aim: Moisturizers have important roles in the treatment of dry skin. Their safety has to be evaluated on human volunteers in order to assess their potential skin irritation. Measurements of skin biophysical parameters can be used as fast and noninvasive methods to assess any harmful effect of cosmetic formulations on the skin sites where those products are applied.
Methods: Two moisturizers were selected from Iran's market to determine the changes in Trans Epidermal Water Loss (TEWL), stratum corneum hydration, pH, melanin and hemoglobin contents by biometric assessments with MPA 580 Cutometer®.
Results: There was no any significant change in TEWL, skin pH, melanin and hemoglobin contents before and after products application. Stratum corneum hydration was increased after application of Neu Derm Renutrive Honey Shea from 0.09 to 0.39 (P0.001). Neu Derm Optimal Hydrosense increased stratum corneum hydration from 0.23 to 0.48 (P0.001).
Conclusion: Application of the studied moisturizers on human volunteers did not show any adverse effect. So, those products could be recommended for safe use. Significant changes in the stratum corneum hydration associated with application of each moisturizer were related to humectant ingredients which were used in each product.
