Journal of

---

Background and Aim: Consumption of the epidermis (COE) is defined as thinning of the epidermis with attenuation of the basal and suprabasal layers and loss of rete ridges in areas of direct contact with malignant melanocytes. The aim of this study was to investigate the importance of COE as an additional diagnostic criterion for malignant melanoma and to evaluate its relationship to clinicopathological findings.

Methodes: The age, gender, localization of the lesion and the histopathological parameters such as tumor type, Breslow thickness, ulceration, and Clark's level were recoeded in 90 malignant melanoma cases.

Results: In contrast to other studies, we found that COE was more common in tumors with an acral localization and in the acral lentiginous melanoma.

Conclusion: Although COE can be used as a pathological criterion in the diagnosis of malignant melanoma, but no correlation no of COE with ulceration and other prognostic factors were found.

---

Background and Aim: Mycosis fungoides (MF) is the most common primary cutaneous lymphoma. Diagnosis of early MF (eMF) is often difficult due to its resemblance of benign dermatoses. The aim of this study was to evaluate the role of provided clinical information on the histopathology request forms for diagnosis of eMF according to the International Society of Cutaneous Lympoma (ISCL) criteria. Methods: In this cross-sectional study, 108 patients admitted to Razi Hospital, Tehran, between April 2012 and November 2013, who were biopsied as eMF cases, were recruited. Based on partial application of ISCL algorithm, the checklist of clinical and histopathological findings were scored. Results: Eighty-five (78.7%) patients received maximum total clinical and histopathological scores (4) and their eMF were definitely diagnosed. Sixteen (14.8%) patients received a total score of 3, and suggestive eMF diagnosis was made. Further work up such as immunohistochemistry (IHC) evaluation were recommended. Seven patients (6.5%) received a total score of 2, which did not confirm eMF diagnosis. Follow up was recommended. In 14 (87.5%) of 16 patients who had received a total score of 3, the definite diagnosis of eMF was made according to the results of IHC. They were referred to receive treatment. In 2 patients (12.5%) diagnosis of eMF were not confirmed by IHC. They were recommended to undergo polymerase chain reaction (PCR) evaluation Conclusion: Many MF cases can be diagnosed in the early stages using a combination of clinical and histopathological criteria.

---

Background and Aim: Distance E-learning has been proved as an efficient modality of learning in medical education. Use of “social media” for e-learning is an emerging issue in medical education. There is no study about WhatsApp in the medical education literature from Iran. To determine the effectiveness of the WhatsApp application, for dermatology education to 6^th year medical students (interns).
 

Methods: This research is a quasi-experimental study. Every month a WhatsApp group was created by mentor as group administrator and all interns joined the group as members. Various cases of Common skin diseases were presented by mentor in the group and using educational method of question and answer, mentor helped Interns to make the correct diagnosis. At the end of 30 days teaching practice schedule, a questionnaire was distributed among the interns and their feedbacks regarding their experience in the group, were gathered.
 

Results: Over a 6-month period, A total of 61 people were included in the study. an average of 50 cases per month were discussed. 97%of the participants were satisfied of using WhatsApp for dermatology education and majority of them found the discussions very useful in improving interpersonal relationship and improving their ability to diagnose real dermatology cases.
 

Conclusion: This study showed that WhatsApp is a suitable tool for teaching dermatology to interns, and the increasing use of this tool will help improving medical education.

---

Background and Aim: Genital wart disease is an infectious disease caused by a type of human papilloma virus that is transmitted through direct contact with the skin of people and mainly as a result of sexual intercourse. Therefore, the profile of psychological vulnerability in people with genital warts and its role in the level of impulsivity It was studied in patients at Razi Hospital.
 

Methods: The current research was of a descriptive-correlation type. The statistical population of the research consisted of all the people referred to Razi Hospital who were suffering from genital warts. 122 people were selected and included in the study. Psychological vulnerability questionnaire and Barat impulsivity questionnaire were used in this research. Data analysis was done with analysis of variance and independent t test, Pearson correlation and stepwise regression and SPSS 18 software.
 

Results: The results showed that psychological vulnerability is normal in people with genital warts. Psychological vulnerability plays a role in impulsivity. Paranoid thoughts have an effect coefficient of 0.3030 and a prediction of 0.30.
 

Conclusion: Considering the role of psychological vulnerability in the formation of behavioral disorders such as impulsivity on the one hand and the role of impulsivity in contracting genital warts on the other hand, this research has practical implications in highlighting the areas of prevention and treatment of impulsivity.