Marjan Oryan, Mohammad Hosein Hakimi Meybodi, Mohammad Ebrahimzadeh Ardekani, Bahman Kiani,
Volume 9, Issue 2 (2018, Volume 9, Number 2 2018)
Abstract
Background and Aim: The use of medicinal herbs for the treatment of skin disease, such as acne, has a long history. The extract of Pistaca atlantica is used to treat various diseases. This study was designed to evaluate the short-term efficacy and safety of Pistaca atlantica extract for the treatment of mild to moderate acne.
Methods: This clinical trial was performed on 60 patients with mild to moderate acne, who where randomly divided into two groups. After obtaining informed consent, volunteers in the case group received a topical extract of 15% Pistaca Atlantica once daily for 6 weeks. In the control group, placebo was given in the same way. Patients were evaluated for the number of lesions at the beginning, and 3 and 6 weeks after treatment.
Results: At the end of study, the mean reduction in lesions was 59.93% in the Pistaca atlantica group and -11.46% in the control group. Also Skin softness and lucidity were observed in the Pistaca atlantica group.
Conclusion: This clinical study showed that topical treatment with Pistaca atlantica extract can be recommended to improve mild to moderate acne. However, a longer study with larger sample size is needed to achieve a comprehensive evaluation of the efficacy and safety of this plant.
