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Showing 3 results for Sadati
Frequency of kerion complications
Iman Ahrari, Ladan Dastgheyb, Zahra Ghazi, Maryam-Ol-Sadat Sadati,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Tinea capitis is one of the most common fungal infections in dermatology. Although the new medications and development in social health have reduced its incidence, it is still common in Iran, especially in rural areas. The aim of this study was to describe the frequency of complications of kerion.
Methods: Eighteen affected patients, who were hospitalized in dermatology ward because of kerion, in a 10-year period, were revisited and according to their medical documents, data collection forms were filled.
Results: 61.1% of the patients were younger than 10 years of age and 77.7% were male. The mean disease duration from the onset of symptoms to the time of correct diagnosis and management was 16.9 days. The frequency of scar and alopecia was equal in all groups and occurred in 100% of patients. Two patients also suffered from isolation due to scarring alopecia. Various types of medications, made no difference in the prognosis and resultant scarring alopecia.
Conclusion: The frequency and types of sequela showed no relationship with age, type of medication and duration from the onset of disease and correct management. Scar and alopecia occurred in all patients. Further investigations on the new treatment modalities are required to reduce scar formation.

Relationship between systemic isotretinoin and induction of depression in acne vulgaris patients
Farhad Handjani, Md, Maryam Sadat Sadati, Md, Ali Firoozabadi, Md, Vala Rezaei, Sara Akramzadeh,
Volume 4, Issue 2 (6-2013)
Abstract
Background and Aim: Acne is one of the most common skin diseases. One of the best treatments is systemic isotretinoin. Some studies link its use with depression, psychiatric problems and suicide, but it is still a matter of debate. So, this study was designed to determine the frequency of depression in acne patients, treated with isotretinoin.
Methods: Fifty-nine acne patients between 16 -30 years old were included. The patients received 0.5-1 mg/kg/day isotretinoin for 16 weeks. At the beginning and at the end of study, the Beck questionnaire was completed by the patients and the results were analyzed.
Results: The mean score of the Beck questionnaire was 13.19 at the beginning of the study and 14.80 after 4 months of treatment with isotretinoin (P=0.0001).
Conclusion: The results of this study showed that isotretinoin may have a small, but still noticeable increase in depression scores of acne patients. However, it is important to consider that various other parameters, such as individual’s psychological status at the time of completing the questionnaire, might influence the results. So, further studies with more patients and longer durations, and the use of other pertinent questionnaires, are recommended.
Lipid profile changes in hospitalized pemphigus patients after treatment with oral prednisolone alone or in combination with adjuvants
Tahereh Soori, Nafiseh Esmaeili, Mostafa Mirshams-Shahshahani, Mohammad Reza Poursadati, Abbas Karimi,
Volume 5, Issue 4 (Volume 5, Number 4 2015)
Abstract

Background and Aim: The standard treatment regimen for pemphigus is adminitration of systemic corticosteroids and adjuvant agents. Previous studies have shown that corticosteroid therapy may alter lipid profile and reduce the atherogenic index in some disorders. This study was conducted to evaluate the changes in lipid profile in pemphigus patients treated with oral corticosteroids alone or in combination with adjuvants.

Methods: In this retrospective corss-sectional study, medical records of 148 pemphigus patients admitted in Razi Hospital in Tehran were reviewed for serum levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholestrol, and triglyceride on the day of admission till 3 weeks after initiation of the treatment.

Results: Fifty-eight percent of patients were female and the mean age of the patients was 47.1 years. 79.3% and 13.3% of patients had been treated with prednisolone plus azathiorine or prednisolone alone, respectively. The remainig patients were treated by administration of oral prednisolone and other adjuvants. Serum levels of LDL, HDL, total cholestrol and triglyceride were significantly higher 3 weeks after initiation of treatment compared to baseline (P<0.05). With the exception of the signifcantly higher level of triglycerides in women, there was no statistically significant association between the levels of other serum lipids at the end of 3 weeks treatment with gender, age, severity of the disease, use of statins, and the treatment regimen (P>0.05).

Conclusion: Although the level of different components of the lipid profile in Iranian patients with pemphigus changed after receiving treatment for 3 weeks, it seems that those changes were not associated with an increased atherogenic index of pemphigus patients.


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