Showing 10 results for Sadeghi
Parvin Mansouri, Soheila Hasouri, Alireza Firooz, Alireza Khatami, Hamed Zartab, Asal Atarod, Reza Chalangari, Katalin Martits Chalangari, Faribroz Sadeghi,
Volume 2, Issue 3 (9-2011)
Abstract
Background and Aim: Atopic dermatitis (AD) is a chronic, relapsing, pruritic skin disease more common in infancy and childhood. Emollients, topical corticosteroids, and avoidance of irritating factors are the mainstay of its treatment, but fear of side effects has limited the use of topical corticosteroids. The objective of this study was to evaluate the safety and efficacy of topical tacrolimus 0.03% ointment in the treatment of AD.
Methods: In this randomized, double-blind, clinical trial, 76 patients with AD older than 2 years were randomly allocated in two groups and treated with either tacrolimus 0.03% ointment (Abu-Rayhan Co., Iran) or placebo, twice a day for 6 weeks. Responses to treatment were compared every 2 weeks using SCORAD.
Results: Twenty-nine patients in tacrolimus group and 26 in placebo group completed the trial. The reduction in SCORAD after 2 and 4 weeks in tacrolimus group was significantly higher than placebo group (P<0/05). The frequency of treatment-induced pruritus and burning sensation was similar in both groups but erythema was more observed in the placebo group (P<0/05).
Conclusion: Tacrolimus 0.03% ointment is more effective than placebo in the treatment of AD.
Anahita Sadeghi, Behrouz Navabakhsh, Gita Shafiee, Maryam Aalaa, Mohammad Bagher Larijani, Alireza Firooz, Vajihe Marsoosi, Azadeh Sayarifard, Hamidreza Aghaei Meybodi,
Volume 4, Issue 4 (12-2013)
Abstract
Despite the large number of patients presenting with hirsutism and high prevalence of polycystic ovary syndrome, for which hirsutism is an important sign, no national guidelines are currently available to Iranian primary-care and family physicians for its diagnosis and management. We have integrated highest levels of evidence and expert consensus to provide a national guideline to standardize and unify the Iranian primary-care and family physician’s approach to hirsutism.
Pedram Nourmohammadpour, Amir Houshang Ehsani, Kambiz Kamyab, Bita Saghi, Hassan Seirafi, Ali Sadeghinia, Fatemeh Gholamali,
Volume 5, Issue 2 (Volume 5, Number 2 2014)
Abstract
Background and Aim: Due to new popularity of cosmetic tattoos especially among women and its potential relationship with sarcoidosis, the present study was conducted to evaluate clinical presentation and some demographic data about tattoo granuloma, as part of non-infectious dermatologic granulomas.
Methods: In this retrospective cross-sectional study, all patients with the histopathological diagnosis of non-infectious granulomatous lesions whom were admitted between at the dermatology clinics at Razi Hospital, Tehran, Iran between March 21, 2007 and March 20, 2012 were included.
Results: A total of 1099 patients were included in the study. The commonest form of granuloma was foreign body granuloma in 511 (46.4%) of the patients and was followed by tattoo granuloma in 102 (9.2%) of the patients. All patients with tattoo granuloma were females whose ages were from 40 to 60 years. The mean±standard deviation age of the patients was 43±8.57 years. Twenty-six (25%) of patients with tattoo granuloma showed sarcoidal pattern, and one case (1%) showed caseouse pattern, after histopathological evaluation of biopsy specimens. Majority of the lesions were papular (32.3%) followed by nodular (24.5%) lesions.
Conclusion: Tattoo granuloma is the second common form of non-infectious granulomas, and in one-quarter of cases has sarcoidal pattern. Considering this finding, it seems reasonable to evaluate these patients for sarcoidosis.
Ramin Taheri, Abbas Ziari, Majid Mirmohammadkhani, Fateme Talebi Kiasari, Elmira Sadeghi Ivrigh,
Volume 7, Issue 1 (Volume 7, Number 1 2016)
Abstract
Background and Aim: Hirsutism as a clinical presentation of hyperandrogenism has a negative impact on the mental health and quality of life. Therefore, determination of its prevalence and associated factors in communities are important. The aim of this study was to determine the prevalence of hirsutism and its associated factors in dormitory students of Semnan University of Medical Sciences in Semana, Iran.
Methods: In this cross-sectional study, all of the female students of Semnan University of Medical Sciences dormitory were given a questionnaire which consists of three parts. The first two sections was designed to collect the demographic data and medical history including past medical history, drug history, menstrual condition and familial history of hirsutism. The third section included the grading scale of Ferrimen-Gallwey, that contains images of various parts of the body and hair growth. Participants were asked to determine their hair growth on the pictures. Data was analyzed using IBM SPSS Statistics (IBM Corp., Armonk, NY, USA) version 19. Chi squared test was used for comparison of proportions in different groups.
Results: From 330 participants, 119 students (36.1%) complained from hirsutism. 105 (31.8%) patients had mild and 14 (4.3%) students had moderate hirsutism. There was a significant correlation between hirsutism and irregular menstrual cycles, positive familial history of hirsutism, congenital adrenal hyperplasia, polycystic ovary, hypothyroidism, use of danazol, and hoarseness (P<0.05).
Conclusion: This study showed a high prevalence of hirsutism in dormitory students of Semnan University of Medical Sciences. More clinical evaluation is suggested to determine various forms of hirsutism and the underlying conditions.
Sepideh Rahmani, Gholamreza Askari, Mehdi Sadeghian, Motahareh Heidari,
Volume 8, Issue 2 (Volume 8, Number 2 2017)
Abstract
Background and Aim: Acne is one of the most common diseases among young individuals. Controversial findings are reported about the effect of glycemic index (GI) and glycemic load (GL) of the diet on acne vulgaris. The aim of this study was to investigate the effect of GI and GL of diet on severity of acne.
Methods: All relevant studies on effects of GI or GL on acne published up to December 2016 were collected using PubMed, Google Scholar, Science direct, Ovid and Cochrane library.
Results: Of 714 articles in our initial research, 6 interventional and 3 case-control studies were included.
Case-control studies revealed that patients with acne vulgaris consumed diets with a higher GI rather than control group. Intervention with a low GI diet reduced lesion counts and improved the severity of acne as well as insulin sensitivity compared with those under high GI diet.
Conclusion: Overall, a diet with low GI and GL could improve acne severity and inflammatory lesions.
Negar Sadeghi, Alireza Moradi, Jafar Hasani, Shahram Mohammadkhani,
Volume 9, Issue 2 (2018, Volume 9, Number 2 2018)
Abstract
Background and Aim: The cosmetic surgery is one of the prevalent phenomenons in recent decades. Body image is a key factor for interest in cosmetic surgery, but body image is a multidimensional concept and all its dimensions should be studied. This study aimed to study cognitive, emotional and behavioral dimensions of body image in women interested in cosmetic surgery.
Methods: This study was a cross-sectional research with causal-comparative method. A sample of 600 female students, age 18 to 35 years, were selected from universities in Tehran by using multi-stage cluster random sampling methid, who completed a set of questionnaires including “Beliefs About Appearance Scale (BAAS)“, “Body Areas Satisfaction Scale (BASS)“, “the Body Image Coping Strategies Inventory (BICSI)“ and Acceptance of Cosmetic Surgery Scale (ACSS). The collected data were analyzed by multivariate analysis of variance (MANOVA).
Results: The students who were interested in cosmetic surgery got a higher score in components of body investment as cognitive dimension and body dissatisfaction as emotional dimension. Among the three behavioral components of body image, there was significant difference only in appearance fixing coping (P<0.0001) and there were no significant differences in acceptance and avoidant strategies between students.
Conclusion: All of the cognitive, emotional and behavioral dimensions of body image are important in cosmetic surgery, and women interested in cosmetic surgery not only had body dissatisfaction, but also had dysfunctional attitudes about appearance important in interpersonal relationships, personal achievement and self-concept, and used strategies based on body modification. These findings can be used in prevention and intervention programs.
Ali Sadeghi Urmia, Babak Barati, Javid Taghinejad,
Volume 9, Issue 2 (2018, Volume 9, Number 2 2018)
Abstract
Cancer is a genetic condition. Some cancers are inherited, but most are caused by mutations in somatic cells. The cause of these mutations is inherent error in the transcription of DNA or exposure to carcinogens. Malignant melanoma is the most serious type of skin cancer which develops from pigment-containing cells known as melanocytes. The most potent risk factors for melanoma is the presence of multiple benign moles or abnormal spots, and family history of melanoma. Metastasis is a complex multi-stage process that results in development of secondary malignant growths and the spread of cancer cells to other areas of the body leading to patient’s death. Melanoma metastases are mainly to the lymph nodes, liver, lungs, and central nervous system. The aim of this article is to review the mechanisms of development and metastasis of melanoma by searching database such as SID, Google Scholar, American Electronic Library,Springer and PubMed.
Negar Sadeghi, Balal Izanloo, Hava Falahati, Mohammadreza Eftekhari,
Volume 9, Issue 4 (2018, Volume 9, Number 4 2019)
Abstract
Background and Aim: The adolescence is one of the phases that adolescents experience significant physical changes during it, these change can causes the changes in body image especially in girls but body image is a psychological phenomenon that be powerfully affected by sociocultural factors. So, it is necessary to study body image in cultural context. The present study aimed to investigate the role of the sociocultural pressures and mediators mechanisms in the development of dissatisfaction among Iranian Adolescent Girls.
Methods: A sample of 250 adolescent girls, ages 15 to 18, were selected from Karaj city by using multi-stage cluster random sampling and responded a set of questionnaires including "The Sociocultural Attitudes Towards Appearance Scale-4 (SATAQ-4)", "Physical Appearance Comparison Scale-Revised (PACS-R)" and "Body Areas Satisfaction Scale (BASS)". The collected data analyzed using Lisrel and was used path analysis method.
Results: The results of the path analysis indicated that the paths of media and peer pressure on internalization had significant coefficients but the path of parent pressure was not significant. Also, the mechanisms of the appearance compare and internalization mediate the relationship of sociocultural pressures and body dissatisfaction.
Conclusion: The results indicate sociocultural perspective can predict the development of dissatisfaction among Iranian Adolescent Girls based on sociocultural pressures and their mediator mechanisms.
Negar Sadeghi, Elahe Faraji, Mostafa Allami,
Volume 11, Issue 3 (Volume 11, No 3 2020)
Abstract
Background and Aim: The aim of present study was to evaluate psychometric properties of the Amputee the Body Image Scale (ABIS).
Methods: A sample of 200 amputee patients were selected from amputee veteran and amputee people under the protection of Red Cerscent by using convenience sampling and asked to respond to the Persian version of The Amputee Body Image Scale (ABIS), Bell Adjustment Inventory (BAI) and Body Areas Satisfaction Scale (BASS). The reliability of the inventory was assessed by internal consistency and item-rest correlations. Also; in order to investigate the validity of the inventory, confirmatory factor analysis, criterion validity and convergent validity were used.
Results: The Cronbach’s alpha (0.89) and item-rest correlations indicated satisfactory reliability of the inventory. The results of confirmatory factor analysis confirmed one factor structure for scale. Also, criterion validity of the scale with the Bell Adjustment Inventory (BAI) and convergent validity of the scale with the Body Areas Satisfaction Scale (BASS) was satisfactory.
Conclusion: The findings showed that the Persian version of the Amputee Body Image Scale is a suitable tool in assessing of body image in amputee patients and can be used in research and intervention fields in Iranian patients.
Ala Ehsani, Bahar Sadeghi, Amirhoushang Ehsani, Mahshid-Ol- Sadat Ansari, Zahra Razavi, Mina Koohian Mohammadabadi, Kambiz Kamyab, Pedram Nourmohammadpour, Mobina Kamalabadi Farahani, Amirhossein Rahimnia,
Volume 15, Issue 3 (Volume 15, No3 2024)
Abstract
Background and Aim: Angiokeratomas are rare vascular lesions, typically presenting as small red to purple macules or papules on the skin. These lesions are usually benign, though they can undergo changes in thickness and color over time. Certain types of angiokeratomas may also signal underlying metabolic disorders, necessitating careful clinical attention. This study aims to analyze the clinical and demographic features of angiokeratoma in Iranian patients at Razi Dermatology Hospital.
Methods: This descriptive, retrospective cross-sectional study examined 199 patients diagnosed with angiokeratoma between 2013 and 2023. Data on demographics, lesion characteristics (location and size), family history, and treatment methods were collected from medical records and analyzed using SPSS. Both parametric and non-parametric statistical tests were applied to assess associations, with a significance level set at 0.05.
Results: The mean age of patients was 24.75 years, with the second and third decades showing the highest prevalence. Among the patients, 51.3% were male and 48.7% female. Lesions most commonly appeared on the lower extremities (40.7%) and genital area (18.6%). Treatment methods included cryotherapy (68.14%), laser (27.14%), and electrodessication (4.44%), with cryotherapy proving the most effective among them.
Conclusion: This study provides valuable insights into the prevalence, clinical characteristics, and preferred treatment approaches for angiokeratoma in Iranian patients. Broader studies across various centers, along with long-term follow-up, are recommended to further investigate the clinical course, therapeutic outcomes, and potential complications associated with different treatment methods.
