Mahmoud Farshchian, Akram Ansar, Mohammad Reza Sobhan, Saadat Torabian,
Volume 4, Issue 1 (3-2013)
Abstract
Background and Aim: Psoriasis is a common chronic inflammatory skin disease. The risk factors of metabolic syndrome have been reported with greater frequency in patients with psoriasis. In this study, we aimed to evaluate these risk factors and compare them with normal population, as the control group.
Methods: In this case-control study, 55 patients with psoriasis were studied from 2011 to 2012 and 55 matched (for sex and age) persons were considered as control group. Age, gender, body mass index, systolic and diastolic blood pressures, smoking, alcohol consumption, type of disease, and blood levels of triglyceride, total cholesterol, LDL, HDL, and fasting sugar were evaluated in both case and control groups and compared.
Results: Our findings showed that levels of TG (P=0.005,OR: 1.02, 95%CI: 1.0-1.34) and LDL (P=0.03, OR: 1.04, 95%CI: 1.0-1.09), the frequency of smoking (P=0.02, OR: 2.2, 95%CI: 1.1-3.2), and the mean of systolic blood pressure (P=0.004, OR: 1.07, 95%CI: 1.02-1.33) were significantly higher in psoriatic patients, compare with control group.
Conclusion: Higher frequency of hypertension and lipid abnormalities in psoriatic patients may enhance the risk of cardiovascular diseases in them. Therefore, we recommend to check all patients with psoriasis, regardless of their disease severity, for serum lipid profiles and blood pressure. In addition, we strongly recommend giving up smoking, as a part of psoriasis treatment.
Ali Asghar Rezanejad, Mohammad Reza Sobhan, Hamid Reza Gsemi Basir, Akram Ansar,
Volume 7, Issue 2 (Volume 7, Number 2 2016)
Abstract
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disease due to benign proliferation of dermal and subcutaneous capillaries. It is most commonly seen in young to middle-age females. Skin lesions include single or multiple red papules, plaques and nodules. It most commonly involves head and neck. Its etiology has not been determined. ALHE lesions are usually resistant to commonly suggested treatment methods including surgery. Recurrence of treated lesions is also common. Herein, we report a 38-year-old pregnant woman who presented with multiple red papules and nodules on her periauricular and occipital skin. Her lesions were confirmed to be ALHE after histopathological assessment.
Mohammadreza Sobhan, Faezeh Mohammadi, Elham Khanlarzadeh, Mohammad Faryadras,
Volume 12, Issue 1 (Volume 12, No 1 2021)
Abstract
Background and Aim: Warts are benign tumors caused by different types of human papillomavirus. Different methods are used in the treatment of warts. The aim of this study was to compare the effectiveness, side effects and number of treatment sessions of CO2 laser and cryotherapy in the treatment of plantar warts
Methods: Seventy patients (140 feet) with plantar warts on both feet who referred to the dermatology clinic of Farshchian (Sina) Hospital in Hamadan during 2019-2020 were selected by convenience sampling method. The warts were randomly treated with either CO2 laser or cryotherapy on each foot. After treatment, patients were evaluated every two weeks for up to five sessions for requirement of treatment repetitions and assessment the extent of healing. In the cases with
non-healing lesion, treatment was repeated once every two weeks for up to five sessions.
Results: The mean age of the patients was 22.11±8.73 years, and 35.7% were male and 64.3% were female. In the CO2 laser and cryotherapy groups, the frequency of recovery rate was 81.4% and 41.4%, (P<0.001), and the mean number of treatment sessions was 1.90±0.84 and 3.55±0.69 (P<0.001) respectively. Frequency and type of side effects in the CO2 laser and cryotrapy group was pain 25.7% and 94.3% (P<0.001), itching zero and 32.9% (P<0.001), blisters 2.9% and 82.9% (P<0.001) and hyperpigmentation with zero and 12.9% (P=0.003), respectively.
Conclusion: CO2 laser is more effective than cryotherapy in less number of sessions and with less side effects for the treatment of plantar warts
