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Mahdi Gheisari, Khalil Forouzannia, Paria Peydayesh, Khatereh Zahedi,
Volume 10, Issue 3 (Volume 10, No 3 2019)
Abstract

Background and Aim: According to the limited clinical observations and researches on cutaneous complications and hair growth changes of donor's site extremities, this study aimed to compare hair growth changes and cutaneous complications of donor's site extremity in patients who underwent coronary artery bypass graft between diabetic and non-diabetic patients.

Methods: Patients who attended the heart surgical clinic for routine follow-up 3-6 months after CABG (coronary artery bypass grafting) were evaluated. Their donor's sites in both extremities were compared with each other. Cutaneous changes were assessed and recorded by a dermatologist. After recording data, the incidence of these complications and the differences between diabetic and non-diabetic patients were evaluated.

Results: From the 97 participants of this study, 77 were male and 20 were female. Of these patients 29 were diabetic. Ten had hypertrichosis, 3 had hair loss in donor's site extremity, 16 had hyperpigmentation changes, 21 had itches, 26 had colloid scar changes, 3 had dermatitis, and 9 had wound site infection. In this study there was no statistically significant difference regarding the incidence of complications in diabetic patients compared to non-diabetic patients (P>0.05).

Conclusion: The cutaneous complications in this study were similar to previous studies and the only significant finding was the incidence of hypertrichosis in donor's site extremity. In order to determine the prevalence and persistence of the complications more accurately, further studies on larger populations including follow-up of complications are warranted.


Farid Mohamadi, Khatere Zahedi,
Volume 16, Issue 2 (Volume 16, No 2 2025)
Abstract

Erosive lichen planus of the genitalia is a chronic inflammatory autoimmune disease primarily affecting the genital mucosa, causing pain, discomfort, and impairing urinary, reproductive, and sexual functions. This condition is more common in postmenopausal women and is often associated with other autoimmune diseases such as vitiligo and thyroid disorders. Standard treatments include topical and systemic corticosteroids, but several challenges persist, especially in cases resistant to conventional therapies. This review discusses novel and alternative treatment options, including immunomodulators and systemic therapies like tacrolimus, secukinumab, and anti-malarial drugs. It also emphasizes the importance of personalized treatment strategies for patients resistant to standard treatments. Additionally, the psychological impacts of the disease on patients’ quality of life and the need for a multidimensional approach in managing these patients are highlighted.
 

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