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Showing 3 results for Zamani
 CRP serum level in patients with psoriasis before and after treatment with narrow-band ultraviolete B
Akram Ansar, Vali-O-Allah Hosseinpoor, Abbas Zamanian, Mahmood Farshchian,
Volume 3, Issue 1 (3-2012)
Abstract
Background and Aim: C-reactive protein (CRP) is an inflammatory biomarker and its level increases in serum of psoriatic patients. Its level is also associated with Psoriasis Area and Severity Index (PASI) score.
Methods: CRP serum levels in patients with psoriasis were measured before and after treatment with narrow-band ultraviolet B (NB-UVB) and the data were analyzed in relation the PASI score improvement.
Results: Baseline CRP levels among psoriatic patients  were higher than normal. These levels decreased significantly after treatment. At the beginning of the study, patients with higher levels of CRP also had more extensive and severe skin involvement. Highest decrease in CRP was observed in patients who responded better to the treatment and acheived higher PASI 75%. There was an association between baseline PASI scores and CRP levels.
Conclusion: Patients with moderate to severe plaque-type psoriasis had systemic inflammation too, which was demonstrated by having higher levels of CRP. Skin disease activity also was associated with higher levels of CRP. Phototherapy healed the psoriatic skin lesions and also reduced inflammation and decreased CRP levels.

Effect of Narrow Band UVB on normal flora of lesional and normal skin in psoriatic patients
Mahmood Farshchian, Elaheh Soltanie, Leila Moosavee, Hossein Mahjoob, Abbas Zamanian, Haleh Nazerian, ,
Volume 3, Issue 2 (6-2012)
Abstract

Background and Aim: Psoriasis is a chronic inflammatory dermatosis that affects 0.6% to 4.8% of the general population. Our aim was to compare the effect of narrow band UVB (NB-UVB) on normal flora of cutaneous plaques and normal skin in psoriatic patients.

Methods: Twenty psoriatic patients without any contraindication of phototherapy were enrolled in this study. Samples from psoriatic lesions and adjacent normal skin, before and after phototherapy with NB-UVB were taken. Patients were treated with NB-UVB three times weekly until complete remission. Finally, quantity of normal cutaneous flora on normal and involved skin, before and after treatment was compared.

Results: The mean±SD of the NB-UVB sessions and the mean cumulative dose were 26.35±4.95 and 2.05±0.57 J/cm2, respectively. The number of Staphylococcus epidermidis, S. aureus and diphtheroids on psoriatic plaques reduced after phototherapy.

Conclusuion: The quantity of normal cutaneous flora on normal skin is less than psoriatic plaques, and it reduced on normal and involved skin after phototherapy.


Chronic itch
Zahrabeigom Moosavi, Shayan Zamani,
Volume 14, Issue 4 (Volume 14, No 4 2024)
Abstract
Itch is one of the commonest complaints of patients of patients in skin clinics. Chronic itch is defined itch lasting more than 6 weeks, which suffers the patients and significantly reduces their quality of life. In this review, we explain pathogenesis and available treatments as a whole. In addition, we summarize pathogenesis and therapeutic options of some common conditions with chronic pruritus, except eczema, such as chronic kidney disease, cholestasis.
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