Showing 104 results for Skin
Asra Asgharzadeh, Sima Marzban, Bahman Amani, Leyla Yavari,
Volume 8, Issue 1 (4-2017)
Abstract
Background and Aim: Microdermabrasion is a minimally invasive technology that is widely used in the field of cosmetic medicine. The mechanism of action of microdermabrasion is mechanical peeling of the skin using metal crystals. This review was conducted to evaluate the safety and efficacy of microdermabrasion in the treatment of scar, acne, striae and its other indications.
Methods: A comprehensive electronic search was done in clinical evidence databases for clinical trials, systematic reviews, health economic evaluations, and health technology studies. The databases and search engines were PubMed, Ovid Medline, Scopus, Turning Research into Practice (TRIP), Center for Reviews and Disseminations (CRD), Database of Abstracts of Reviews of Effects (DARE), National Health System Economic Evaluation Database (NHS EED), Health Technology Assessment (HTA), Cochrane Library, and ClinicalKey. The search was done up to July 2014. Key references were manually searched to find relevant studies. The eligible articles were investigated regarding the safety and efficacy of microdermabrasion.
Results: This systematic review includes 19 studies with a total of 368 patients, whom were treated with microdermabrasion for treatment of acne, vitiligo, melasma, acne scars, striae, skin rejuvenation, photo damaged skin and, photo-aging. Appraisal of the studies supported the efficacy and safety of microdermabrasion in treating the aforementioned skin problems.
Conclusion: Microdermabrasion, either as a single therapeutic intervention or in combination with other interventions, can be used in the treatment of several skin diseases and conditions. Since its side effects are milder than some other interventions, generally, it is considered as a safe method.
Fatemeh Fadaei, Ebrahim Khadem,
Volume 8, Issue 1 (4-2017)
Abstract
Iranian traditional medicine (ITM) scholars have explained the structure and function of each organ based on clinical observations and past experiences. The skin is especially important due to apparent clinical manifestations serving as a convenient diagnosis tool. This study was aimed to evaluate the anatomy and physiology of the skin as presented in ITM School and compare with conventional medicine. Relevant keywords were searched in ITM reference books, Google scholar, PubMed, and Scopus. After extracting the data, the results were classified in terms of concepts and tables.
ITM scholars believe the embryonic origin of skin is similar to nervous tissue. In their view, the skin has a moderate temperament, and is a combination of fibers, nerve ends, muscles and vessels. Among the most important functions of the skin is the sense of touch, body temperature regulation, and excretion of wastes.
In conventional medicine, the skin consists of epidermis, dermis, and hypodermis layers. The embryonic origin of epidermis is the ectoderm. Protection and body temperature regulation, sensory activities, gas exchange, absorption of ultraviolet rays and disposal of excess body electrolytes are considered as the most important skin functions.
Overview of fetal origin, structure and function of the skin between these two schools of medicine interpreted in many ways, revealed many similarities.
Robabeh Abedini, Vahide Lajevardi, Azadeh Goodarzi,
Volume 8, Issue 3 (10-2017)
Abstract
Nowadays, in modern medicine, there is a great tendency to use non invasive or less invasive diagnostic and therapeutic methods with high precision and effectiveness. This is also true about diagnosis and treatment of non-melanoma skin cancers (NMSCs), that the prototypes are basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) which also considered as the most common human cancers. Therefore, in this review, we present the value and diagnostic features of the dermoscopy (as an emerging and growing non-invasive dermatological evaluation tool) for approaching to NMSC. It is hoped that this study will be an infrastructure for the ever-increasing use of dermoscopy in evaluation of skin cancers, especially NMSCs.
Salar Hooshyar, Shohreh Nafisi, Khadijeh Ashtari, Bita Mehravi,
Volume 8, Issue 4 (1-2018)
Abstract
Diseases of the skin can cause harm and emotional distress in patients. The desirable drug is one with least complications and most effectiveness. By prolongation of target exposure, drug effectiveness could be improved. There are several suggested solutions, including the use of chemical enhancers, electroporation, iontophoresis, and the use of nanoparticles as carriers of pharmaceutical agents. The use of various nanostructures, including liposomes, dendrimers, autosomes, and many mineral nanoparticles, have been proposed to prevent the limitations with conventional formulations. Topical drug delivery has many benefits, including using high concentrations of the drug and reducing systemic passage of medicament. Many skin products, such as Estrasorb, Diractin and Aczone are available in the market with new and different manufacturing techniques for more skin penetration.
This paper introduces new approaches to drug delivery, types of nanocomposites and methods for increasing the penetration of pharmaceutical agents in the skin. Various factors such as physicochemical properties and the size of nanoparticles, as well as the effects of manipulation on the surface of these particles, have been discussed.
Fateme Fadaei, Ensieh Arefi, Ebrahim Khadem,
Volume 8, Issue 4 (1-2018)
Abstract
The skin is the largest organ of the human body, the first protective barrier of the body and one of the important excretory organs. In conventional medicine, there is great focus on skin rashes to help to diagnose the internal illnesses. Persian medical scholars have also studied a wide range of internal disorders by examining skin manifestations. The aim of this study is to investigate the etiology and semiology of various skin rashes and manifestations from Persian and conventional medicine viewpoints, and to clarify similarities and differences between them. For this purpose data corresponding with key words was extracted from reference books and then relevant scientific databases including Google scholar, PubMed, Web of Science, Scopus and reliable sources like Janquira histology, Habif and Savin's dermatology books were examined. An overview of the cutaneous rash and diseases, revealed that in many cases, these two schools of medicine are not comparable. However, in some cases, such as etiology, description, clinical signs, diagnosis, etc., serious similarities in topic of rashes, skin manifestations and chronic diseases are mentioned in the overview of this two medical schools.
Mina Abdi Zenab, Mohammadali Besharat, Seyed Masoud Davoudi,
Volume 9, Issue 1 (4-2018)
Abstract
Background and Aim: Skin diseases are associated with a set of psychological disorders that not only affects the patient, but also has a huge burden on the patient’s family and the wider society. The main purpose of the present study was to compare the severity of psychologic symptoms in patients with skin diseases and healthy participants.
Methods: In this study, 305 participants aged from 16-85 years (153 cases and 152 controls) were enrolled. Data including demographic variables, in addition to psychiatric variables such as Depression, Anxiety, Stress Scale (DASS), Maudsley Obsessive Compulsive Inventory (MOCI), Eysenck Personality Questionnaire (EPQ) were collected by asking participants to complete questionnaires. The data were analyzed with t test and variance analysis.
Results: There was no significant difference between case and control groups regarding the prevalence of depression, anxiety, compulsive washing and neuroticism. However, there was a significant difference in checking, extroversion and lie. No significant relation was found between age, sex, education, marital status, occupation and history of mental illness with psychological symptoms of patients. A significant relation was observed between the history of suicide and the history of mental illness in the family of patients with extraversion.
Conclusion: Correlation and interaction between skin disease and symptoms of mental disorders is complicated and needs further investigations.
Leyla Miranzadeh, Fathollah Gholami Borujeni,
Volume 9, Issue 1 (4-2018)
Abstract
Background and Aim: Skin cancer is one of the most common cancers in the world, and in many parts of Iran is ranked first to second in number. However, its epidemiology has not been reviewed and studies are limited in Kashan city. This study was conducted to determine the frequency of skin cancers in this city.
Methods: Data were collected using recorded data in Pathology Laboratory of Kashan University of Medical Sciences during years 2009 to 2017. UV index (UV-I) data over the period (2009-2017) were obtained from well-known meteorological sites. Data were analyzed by descriptive and inferential statistics (Chi-square test and MANOVA) using SPSS software version 16.
Results: Skin cancers totally constituted 26.4% of all cancers in Kashan during 2009-2017. 79% of them were basocellular type. Frequenty of spinoscellular and malignant melanoma were 16% and 3%, respectively. The mean age of patients with skin cancers was 48 years. Men showed higher incidence base cellular of cancer than women. The long-term survey of the UV index in the Kashan city showed that in eight months of the year, it was higher than 6 (high to high risk).
Conclusion: Skin cancer is one of the most common cancers in the city of Kashan, especially in men. Educational programs should be developed and conducted to prevent and reduce risk of skin cancer among residents in this city.
Keyvan Ezimand, Ataolah Abdolahi Kakroodi, Mohammad Javanbakht,
Volume 9, Issue 1 (4-2018)
Abstract
Background and Aim: Environmental and climatic conditions in different geographical areas provide the basis for certain diseases. Skin cancer is one of the most common types of cancer, with a different incidence rate in geographical areas. The aim of this study is to determine the effects of climate and environmental factors on skin cancer and to map the geographical distribution of skin cancer in Iran.
Methods: This study was performed using data of patients with skin cancer, population and data of climatic and environmental factors that affect skin cancer incidence. In this study, after calculating the incidence of skin cancer rate for the whole country, we used the Geographically Weighted Regression model to establish a regression relationship between climate and environmental data and the incidence of skin cancer. The coefficient of detection between the map of incidence of skin cancer and its model map was calculated.
Results: Correlation coefficients showed that sun UV and relative humidity had the highest positive and negative correlation with the incidence of skin cancer, respectively. The southern, eastern and central regions of Iran had the highest incidence of skin cancer rate and the northern and northwestern coasts of Iran had the lowest incidence rate. Validating of actual incidence rate map and the modeled incidence rate map indicated a coefficient of detection of 0.71.
Conclusion: All of the climate and environmental parameters in this study contributed to in the incidence of skin cancer.
Sara Hashemi, Aliakbar Yahyaee,
Volume 9, Issue 3 (10-2018)
Abstract
Background and Aim: Skin cancer is the most common malignancy in the world with high morbidity. The aim of this study was to determine the effect of stress inoculation training on quality of life and life expectancy in patients with skin cancer.
Methods: This research was a semi experimental study with pre test - post test - follow up assessment in experimental and control group. The study population consisted of all male patients with skin cancer at Negah Clinic Center in Saveh during the year 2017. Thirty patients were recruited by randomization followed by random allocation dividing them into two groups of 15 subjects. The training included 6 weekly sessions and subjects were asked to fill quality of life and life expectancy questionnaires both at the beginning and end of the coarse. Data was analyzed using ANOVA with repeated measure.
Results: There was a significant difference in life expectancy between the experimental group and control group (P<%001). Furthermore, similar significant difference was found between two groups regarding quality of life.
Conclusion: Stress inoculation training can be used as a valuable and practical intervention in patients with skin cancer,which leads to a significant improvement both in quality of life and life expectancy.
Seyede Zahra Emami Razavi, Maryam Hoseini, Mohaddeseh Azadvari, Zahra Saffarian,
Volume 10, Issue 1 (4-2019)
Abstract
Acupuncture is an ancient medical procedure that is commonly used. It has been used in China for over two thousand years. Acupuncture has gained increasing interest from the public as well as health professionals for a wide range of disorders. This method works through regulation of qi current (life energy in body). Acupuncture has been introduced recently in dermatology for rejuvenation and treatment of facial wrinkles and improving muscle tone and elasticity. Acupuncture is used for treatment of many medical conditions including skin disorders. Tiny, sterile, needles are inserted along meridian lines and acupuncture points to increase blood circulation. Cosmetic acupuncture is a totally natural and holistic anti-ageing treatment that aims to reduce fine lines and wrinkles. Different mechanisms have been proposed for cosmetic acupuncture, including increasing muscle elasticity, and restoring muscle tone. There have been also evidence of increase in skin moisture and lipid.
In this method, body points and local facial points are used and usually 10-12 sessions of facial acupunctures are recommended. With the increasing popularity of complementary therapies in the community, acupuncture is also considered as a new therapeutic approach.
Farnaz Mohammadhedayati, Mohammadtaghi Ahady, Shagayegh Manouchehri,
Volume 10, Issue 2 (8-2019)
Abstract
Background and Aim: Demodex is a common mite and ectoparasite in humans and animals. The existence of Demodex folliculorum and Demodex brevis in human skin can have a role in some inflammatory skin diseases such as acne, rosacea, and dermatitis. This study aimed to identify the prevalence of Demodex ectoparasite in women and its possible association with skin lesions.
Methods: Fifty women with skin lesions (case group) and 50 women without skin lesions (control group) were selected and evaluated by clinical and
laboratory tests. The study was approved by the Ethics Committee and the volunteers provided written informed consent. The skin scrapings were investigated by placing in a 10% potassium hydroxide (KOH) and lactophenol solutions and were analyzed under microscope to detect the Demodex.
Results: Twenty-two out of 50 patients (with acne, rosacea, dermatitis, and eczema) had Demodex folliculorum infestation (44%). The highest levels of infestation were observed in women aged 20-30 years (22%) and the infestation of Demodex was only confirmed in 10 cases (20%) out of the 50 subjects in the control group.
Conclusion: The rate of Demodex in patients with skin lesions was much higher than healthy subjects. There was a significant association between Demodex and skin lesions (sig.=0.023, P<0.05). The authors suggest that Demodox treatment should be considered in the therapeutic strategy of some inflammatory skin diseases.
Mahdi Gheisari, Khalil Forouzannia, Paria Peydayesh, Khatereh Zahedi,
Volume 10, Issue 3 (11-2019)
Abstract
Background and Aim: According to the limited clinical observations and researches on cutaneous complications and hair growth changes of donor's site extremities, this study aimed to compare hair growth changes and cutaneous complications of donor's site extremity in patients who underwent coronary artery bypass graft between diabetic and non-diabetic patients.
Methods: Patients who attended the heart surgical clinic for routine follow-up 3-6 months after CABG (coronary artery bypass grafting) were evaluated. Their donor's sites in both extremities were compared with each other. Cutaneous changes were assessed and recorded by a dermatologist. After recording data, the incidence of these complications and the differences between diabetic and non-diabetic patients were evaluated.
Results: From the 97 participants of this study, 77 were male and 20 were female. Of these patients 29 were diabetic. Ten had hypertrichosis, 3 had hair loss in donor's site extremity, 16 had hyperpigmentation changes, 21 had itches, 26 had colloid scar changes, 3 had dermatitis, and 9 had wound site infection. In this study there was no statistically significant difference regarding the incidence of complications in diabetic patients compared to non-diabetic patients (P>0.05).
Conclusion: The cutaneous complications in this study were similar to previous studies and the only significant finding was the incidence of hypertrichosis in donor's site extremity. In order to determine the prevalence and persistence of the complications more accurately, further studies on larger populations including follow-up of complications are warranted.
Leila Shahmoradi, Reza Moghadasali, Farhad Mostafaei,
Volume 10, Issue 4 (1-2020)
Abstract
Background and Aim: Mobile-based applications have the potential to increase the awareness of skin patients to their disease. The main goal is to rise clients' information about their skin disease, skin cell therapy and to provide Rooyan’s Center informations, specialists list, addresses, presentations, clips and relevant photos of the disease.
Methods: To identify the information, a researcher-made questionnaire was used. The questionnaires were validated by experts. Information system software was designed and developed using Joapp's Windows software. Finally, it was evaluated using a standard questionnaire assessing user satisfaction and program usability.
Results: Users evaluation in four axes: software performance with average (81.3%), Software display with average (78.9%), Software terminology and information with average (68.1%), the overall software capability (82.8%) and the overall mean score of 77.7% were rated as "good".
Conclusion: Treatment of this disease is necessary and important due to mental stress. Due to the inefficiency of existing treatments, complementary therapies to control the disease are on the rise. The software gives patients a broader view of their disease and has been very useful and effcient.
Mozhgan Soltani, Zohre Latifi, Shokoofe Moosavi,
Volume 10, Issue 4 (1-2020)
Abstract
Background and Aim: The purpose of the present study was to asses a the effect of self-healing education on self compassion, body image, concern and improvement of disease process in women with skin cancer.
Methods: A quasi-experimental research with pre-test, post-test and follow up with control group was conducted. The population included all women with skin cancer referring to Shahid Rahimi Hospital in Khorramabad city during 2018to2019. Thirthy four volunteers were selected and randomly assignes into two experimental and control groups (each group sequential included 16-18 people). All participants in the experimental and control group completed the self-compassion questionnaire, body image concern and clinical data on cancer course as a pretest. Education of self-healing therapy was performed for 12 sessions of 90 minutes on the experimental group, but the control group did not receive the intervention. At the end for both groups, the post-test was performed and follow up was done up to two months. Data were analyzed by SPSS software version 19.
Results: Self-healing approach increased self-compassion including: self-kindness, correct judgment, common humanity sense, mindfulness (P<0/01) and decreased body image concern, isolation and over identification (P<0/05) levels in women with skin cancer. Although self-healing education affected improvement process in skin cancer but this effectwas not statistically significant.
Conclusion: Self-healing approach improves self-compassion and reduces body image concern in women with skin cancer.
Zahrabeigom Moosavi, Alireza Firooz,
Volume 11, Issue 1 (4-2020)
Abstract
Since the beginning of COVID-19 pandemic on December 2019, challenges on economic, political, social, hygiene- therapeutic and life style have emerged in many countries. Many researches are investigating on virus characteristics and its behavior and also preventive and therapeutic measures. Despite the virus not being dermatotropic, several skin manifestations have been observed. In this review, overall informations on this viral infection with focus on skin manifestations are presented.
Delara Amirdastmalchi, Amirhooshang Ehsani, Maryam Nasimi, Vahideh Lajvardi, Pedram Noormohamadpoor,
Volume 11, Issue 1 (4-2020)
Abstract
COVID-19 was announced pandemic by March 2020. Due to the high prevalence of the disease and its staggering spread, it is very important to identify various manifestations of this viral infection.
The aim of this study is to review published articles about cutaneous involvement of COVID-19 disease.
Cutaneous manifestations are rare in COVID-19 disease and it is essential to recognize these possible skin manifestations in order to detect and treat COVID-19 disease and to prevent further transmission.
Atefeh Naeimifar, Saman Ahmadnasrollahi,
Volume 11, Issue 1 (4-2020)
Abstract
Knowledge about environmental factors that are aggressive to skin has increased in recent years. Although concern previously focused primarily on UVA and UVB, this has broadened to contain damage from pollution, tobacco smoke, other ambient toxins, infrared light, blue light and UVA-II.
This article reviews the negative effects of infrared, blue light and UVA-II on skin. Potential protective actions also are discussed.
Zahrabeigom Moosavi, Alireza Firooz,
Volume 11, Issue 2 (7-2020)
Abstract
COVID-19 is nowadays a pandemic disease. It affects various aspects of human life including physical and mental health and also socio-economic situations. In this review, we attempt to present a brief selection of abundant published papers about pathogenesis, skin manifestations, treatment challenges in different conditions and prevention.
Hamidreza Ahmadi Ashtiani, Amirreza Noori Garmroodi, Alireza Firooz,
Volume 11, Issue 2 (7-2020)
Abstract
Wounds are any type of tissue dehiscence which can occur on skin, mucosae or connective tissue. After the wound has created, inflammatory process, the immune system changes as well as the skin repair cascade will be activated. To provide a product that can direct the above processes in a desirable repair mechanism will be useful. Studies have shown that aloe vera products, with effects such as increased collagen production, antioxidant and water retaining properties, are good options.
Aloe vera grows mainly in arid regions and this fact can be welcomed in many parts of the world. The use of medicinal herbs also reduces the cost for the health systems. Aloe vera is a plant that does not require much cost for plant and harvest. Besides, the compatibility of aloe vera products with a variety of formulations encourages formulators to use it in the pharmaceutical and cosmetic industries.
In this review, the use of aloe vera in wound management and some skin diseases will be discussed.
Javad Rahmati, Hojjat Molaei Goorchinghalea, Shahriar Hadady Abianeh,
Volume 11, Issue 2 (7-2020)
Abstract
Introduction: Medial canthus area, as one of most common sites of facial skin cancers, is notified for reconstruction. There are numerous reconstructive options to cover resulted skin defects, which have their own advantages and disadvantages. Here, we decided to present our experience in medial canthal area with amazing result.
Case Report: A 47-year-old man with basal cell carcinoma (BCC) of right medial canthus, without extra involvement, was admitted. Following lesion excision with safe margin, the resulted skin defect in 30 mm diameter was reconstructed with full thickness skin graft from posterior auricular area. Several months later, it was really difficult to find scar or operated skin, as supported by complete patient`s satisfaction.
Conclusion: The space between eyes has unbelievable aesthetic and social importance. Any added scar or incision to this area is always challenging. It seems full thickness skin graft - if harvested from proper donor site - can be acceptable in long term aesthetic outcome compared to other reconstructive options.
