Showing 36 results for Kashani
Amirhoushang Ehsani, Arezou Jammanesh, Amirali Jahanshahi, Elnaz Khosravani, Reza Robati, Zahra Saffarian, Alireza Firooz, Vahide Lajevardi, Parvin Mansouri, Mansour Nassiri Kashani,
Volume 13, Issue 4 (Volume 13, No 4 2023)
Abstract
Urticaria is a common and challenging skin disorder. Diagnosis and treatment of urticaria is not limited to the field of dermatology. General physicians, internal medicine specialists, allergologists and clinical immunologists are also commonly involved in the management of patients with urticaria.
Iranian Society of Dermatology developed a clinical practice guideline concerning diagnosis and treatment of urticaria that was published in 2018. The current guideline is the result of scientific papers that got published from April 2018 to August 2022.
Mansour Nassiri Kashani,
Volume 14, Issue 1 (Volume 14, No 1 2023)
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Mansour Nassiri Kashani,
Volume 14, Issue 2 (Volume 14, No 2 2023)
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Hasti Ahmadian Yazdi, Alireza Firooz, Mohsen Rezaeian Vaghar, Elahe Kashani, Aniseh Samadi,
Volume 14, Issue 2 (Volume 14, No 2 2023)
Abstract
Background and Aim: In order to overcome the local side effects of the conventional treatments for atopic dermatitis, a new attitude regarding alternative treatments would be needed, which herbal medicines are promising approachs in this case.
Methods: It was a 4-week, before-after clinical study, conducted on 20 participants (16 women and 4 men) aged 39.95±11.04 years. The severity scoring of atopic dermatitis was determined based on total & local SCORAD. skin biophisical parameters including TEWL ,skin hydration, pH, temperature, sebum and skin erythema were also measured after 2 and 4 weeks application of the study product. Participants’ satisfaction as well as tolerability of the product were assessed by monitoring the adverse effects.
Results: A significant improvement was detected in LOCAL and TOTAL SCORAD at weeks 2 and 4 (P<0.01). The intensity of burning and pruritus also showed a significant decrease at weeks 2 and 4 (P<0.01). A significant increase in the skin hydration was shown at weeks 2 and 4 after treatment (P<0.01). 84.1% and 78.9% of participants described their skin lesions as "improved" or "much improved", 2 and 4 weeks after treatment respectively.
Conclusion: The test cream containing oats and chamomile extract is considered a safe and effective product for improving mild to moderate lesions of atopic dermatitis.
Taraneh Yazdanparast, Mansour Nassiri Kashani, Mansour Shamsipour, Fariba Izadi Heidari, Fateme Amiri, Alireza Firooz,
Volume 14, Issue 2 (Volume 14, No 2 2023)
Abstract
Background and Aim: Allergic contact dermatitis is the most frequent cause of eyelid dermatitis; but it is often misdiagnosed. This study aims to evaluate the characteristics of patients with eyelid dermatitis who referred for patch test.
Methods: This was a retrospective study. Three major subgroups were made: patients with only eyelid involvement, involvement of eyelids and other areas, and without eyelid involvement. Collected data included past history, diagnoses, personal care product & make-up use, occupational dermatitis, and positive allergens. Chi-squared, independent t-test, and one-way ANOVA were used for analysis.
Results: 139 patients with eyelid dermatitis who referred for patch test were included in the study. Allergic contact dermatitis was the most common diagnosis in all three groups referred for patch test. Use of shaving cream and hair conditioner was significantly higher in patients with only eyelid involvement and nickel sulphate was the most common allergen among them.
Conclusion: Patch testing is an important tool in the evaluation of the common dermatologic disease of eyelid contact dermatitis, as the gold standard. It is a necessity in the treatment of eyelid dermatitis, because of accurate identification of responsible allergens.
Mansour Nassiri Kashani,
Volume 14, Issue 3 (Volume 14, No 3 2023)
Abstract
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Aniseh Samadi, Mansour Nassiri Kashani, Azin Ayatollahi, Zahrabeigom Moosavi, Hasti Ahmdian Yazdi, Alireza Firooz,
Volume 14, Issue 4 (Volume 14, No 4 2024)
Abstract
Background and Aim: Recently, many Iranian companies have started manufacturing hyaluronic acid based dermal fillers. Current review aimed to assess and compare the clinical safety and efficacy of 5 Iranian hyaluronic acid based dermal fillers.
Methods: The first part of the study reported, the overall safety and efficacy of 5 Iranian hyaluronic acid based dermal fillers for improvement of nasolabial folds in 150 participants (age 44.30±9.97 years) using clinical and objectives assessment methods. In the second part, we performed a comparative study among 5 tested dermal fillers.
Results: Generally, at weeks 2, 12, and 24, 80.6%, 63.3%, and 60.66% of the participants, showed one grade or more improvement in the severity of nasolabial folds respectively. In all visits, the nasolabial folds biophysical parameters as well as the echo density dermis improved significantly compared to baseline. In comparative study, two fillers with the hyaluronic acid concentration of 24 mg/ml, showed the best objective efficacy, while in clinical evaluations, the filler containing mannitol has the best performance in reducing the severity of nasolabial folds showed.
Conclusion: Iranian hyaluronic acid based dermal fillers showed different levels of safety and efficacy for improvement of moderate to severe nasolabial folds, with efficacy.
Mansour Nassiri Kashani,
Volume 14, Issue 4 (Volume 14, No 4 2024)
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Mansour Nassiri Kashani,
Volume 15, Issue 1 (Volume 15, No 1 2024)
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Tayebeh Momeni, Alieh Safamanesh, Faezeh Kashanian,
Volume 15, Issue 1 (Volume 15, No 1 2024)
Abstract
Chitosan biopolymer, due to its antimicrobial, anti-inflammatory, and antioxidant properties, has become an ideal candidate for use in a wide range of cosmetic products and has opened up new horizons in the design of cosmetic formulations. The ability of this polymer to electrostatically interact with negatively charged surfaces (such as damaged skin) leads to the formation of polymeric films and ultimately imparts smoothness and moisture to cosmetic products. This review article revisits the potential of chitosan and its derivatives as raw materials in cosmetic and skincare products.
Mansour Nassiri Kashani,
Volume 15, Issue 2 (Volume 15, No 2 2024)
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Tayebeh Momeni, Alieh Safamanesh, Faezeh Kashanian,
Volume 15, Issue 2 (Volume 15, No 2 2024)
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Curcuma zedoaria, an aromatic plant from the ginger family, has gained attention for its medicinal properties. In traditional medicine, Curcuma zedoaria has been used as an anti-inflammatory, antibacterial, antifungal, and analgesic. Recent scientific research has revealed significant benefits of Curcuma zedoaria for skin health. Curcuma zedoaria contains curcumin, a powerful anti-inflammatory compound that can help reduce skin inflammation, redness, and swelling. This makes Curcuma zedoaria a suitable option for treating acne, eczema, and psoriasis. Curcumin in Curcuma zedoaria also possesses strong antioxidant properties that can help protect the skin from damage caused by free radicals. Additionally, curcumin can promote collagen and elastin production, which are essential for wound healing. The antimicrobial properties of curcumin can aid in combating bacteria and fungi that cause skin infections. Curcuma zedoaria also exhibits anticancer properties that can help prevent the growth of skin cancer cells. Therefore, Curcuma zedoaria is a natural and safe plant that can help treat a wide range of skin problems. This review article explores the various benefits of Curcuma zedoaria for the skin.
Mansour Nassiri Kashani,
Volume 15, Issue 3 (Volume 15, No3 2024)
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Erfan Zamani, Shayan Zamani, Mansour Nassiri Kashani, Alireza Firooz,
Volume 15, Issue 3 (Volume 15, No3 2024)
Abstract
This review study examines the effects of oral collagen supplementation on various biophysical properties of the skin, including hydration, elasticity, and wrinkle reduction. Collagen, as the most abundant structural protein in the skin, plays a vital role in maintaining its firmness, elasticity, and moisture. With aging, collagen production declines, leading to visible signs of aging such as wrinkles, sagging, and dryness of the skin. Additionally, factors like UV radiation and environmental pollutants accelerate collagen degradation, contributing to premature skin aging. In recent years, oral supplements containing hydrolyzed collagen, particularly collagen peptides, have gained significant popularity due to their potential ability to stimulate collagen production and improve skin quality. Various studies indicate that regular consumption of these supplements can significantly increase skin hydration, enhance elasticity, and reduce the depth and number of wrinkles. However, there are notable limitations in the existing studies, including variations in dosage, intervention duration, and collagen sources. Moreover, many of these studies have small sample sizes and short intervention periods, which limit the validity of the results. Additionally, the presence of other ingredients, such as vitamin C and hyaluronic acid in some supplements, makes it challenging to isolate the direct effects of collagen. Despite these challenges, the existing evidence suggests that oral collagen supplementation holds high potential as an effective approach for addressing skin aging. However, further long-term studies with larger sample sizes and more diverse populations are necessary to determine the precise mechanisms and optimal dosage, thereby providing more definitive scientific recommendations.
Mansour Nassiri Kashani,
Volume 15, Issue 4 (Volume 15, No 4 2025)
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Mansour Nassiri Kashani,
Volume 16, Issue 1 (Volume 16, No 1 2025)
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Aref Nassiri Kashani, Tarane Yazdanparast, Fateme Amiri, Mansour Nassiri Kashani, Alireza Firooz, Mahdi Gheisari,
Volume 16, Issue 1 (Volume 16, No 1 2025)
Abstract
Background and aim: Macular amyloidosis (MA) is a form of primary localized cutaneous amyloidosis (PLCA), characterized by amyloid deposits in the papillary dermis. This study aimed to compare the biophysical properties of MA lesions with those of adjacent uninvolved skin.
Methods: We measured several parameters in active MA lesions of 22 patients, including stratum corneum (SC) hydration, transepidermal water loss (TEWL), surface friction, pH, sebum, melanin, erythema, temperature, elasticity parameters (R0, R2, and R5), as well as epidermal and dermal thickness and echo-density using ultrasonography. Measurements from the lesions were compared with those from healthy skin adjacent to the lesions, serving as controls. Statistical analysis was performed using the paired t-test, with P-values less than 0.05 considered significant.
Results: Compared to adjacent normal skin, MA lesions demonstrated significantly lower SC hydration and surface friction, while TEWL, pH, erythema index, melanin content, and epidermal thickness were significantly increased. No significant differences were found in sebum levels, temperature, elasticity parameters, or dermal thickness and echo-density.
Conclusion: MA lesions exhibit distinct biophysical and ultrasonographic changes consistent with their histopathological features. These characteristic alterations may serve as useful, non-invasive markers for the early diagnosis of cutaneous macular amyloidosis.
Mansour Nassiri Kashani,
Volume 16, Issue 2 (Volume 16, No 2 2025)
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Mansour Nassiri Kashani,
Volume 16, Issue 3 (Volume 16, No 3 2025)
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Aniseh Samadi, Mansour Nassiri Kashani, Azin Ayatollahi, Hamed Zartab, Maryam Ahmadi, Alireza Firooz,
Volume 16, Issue 3 (Volume 16, No 3 2025)
Abstract
Background and aim: In recent years, increasing demand for aesthetic treatments in Iran and the need for high-quality domestic products have encouraged several companies to produce botulinum toxin type A. This study aimed to evaluate and compare the clinical efficacy and safety of three such Iranian products.
Methods: In the first part of the study, the overall efficacy of the botulinum toxin type A products for treating glabellar lines was assessed in 230 participants who received one of the three Iranian formulations (mean age 42.69 ± 9.21 years), and compared with 230 participants who received the standard treatment (Dysport®) (mean age 42.50±9.79 years). Outcomes were evaluated on day 30 post-injection. In the second part, the comparative efficacy of the three domestic products during the same period and their safety profile up to month four post-injection were assessed.
Results: A clinically meaningful response (at least a two-grade improvement in glabellar line severity) was achieved in 68.6% of recipients of the Iranian products, compared with 52.8% of Dysport recipients, demonstrating a statistically significant superiority in equivalence studies (P<0.01). Among the three domestic products, only product No. 2 showed a significantly higher proportion of participants achieving ≥2-grade improvement (assessed by an independent physician). The type and frequency of adverse events (except for headache) were comparable to the standard drug monograph.
Conclusion: The findings indicate acceptable efficacy and safety of Iran-made botulinum toxin type A products compared with the reference product. Except for limited differences, the efficacy and safety profiles of the three formulations were generally similar up to day 30 post-injection.
