Showing 65 results for Hossein
Amirhoushang Ehsan, Mahboobe Sadathosseini, Zahra Hallaji, Amirreza Hanifnia, Masoume Rohaneinasab,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Palmoplantar pustulosis is a chronic dermatosis of palms and soles, which is associated with a high recurrence rate and resistance to treatment. Various treatments with different success rates have been used.The purpose of this study was to evaluate the efficacy of local bath PUVA in the treatment of palmoplantar pustulosis.
Methods: In this retrospective study, patients with palmoplantar pustulosis who were treated with local bath PUVA in Phototherapy clinic of Razi Hospital between 2005 and 2009 were evaluated for the therapeutic efficacy of local bath PUVA. Data were analyzed using t and chi-square tests.
Results: Ninety-five patients with a mean age of 44.17 years included in this study. 49.5% of patients were males and 50.5% were females. Mean treatment cessions of patients were 42.5 sessions and mean cumulative dose was 251.8 J/cm2. In 16.8% of cases have very good response was observed. Good, moderate and poor responses were observed in 35.8%, 29.5% and 9.5% of cases, respectively. Treatment failure was observed in 8.4% of patients. Mean cumulative dose in patients with very good response was significantly higher than other response groups, (P=0.016). Mean number of treatment sessions was also significantly higher in that group with comparison with other groups, (P<0.05). Twenty percent of patients withdrawed from the study because of complications. However all complications recovered completely and no long term complications was observed.
Conclusion: This study demonstrated that local bath PUVA is an effective safe treatment for the treatment of palmoplantar pustulosis.
Ali Ebrahimi, Md, Mansour Rezaei, Phd, Habibollah Khazaei, Md, Hossein Kavoussi, Md, Nooshin Nani,
Volume 4, Issue 2 (6-2013)
Abstract
Background and Aim: Irritant contact dermatitis of hands is a chronic and recurrent cutaneous disorder following the contact with detergents and chemicals. Obsessive compulsive disorder is highly frequent among dermatologic patients, and may be presented with signs of irritant contact dermatitis of hands. The aim of this study was to assess the frequency and relationship between obsessive compulsive disorder and irritant contact dermatitis, among women with chronic and recurrent irritant contact of hands dermatitis in Haj Daie Dermatology Clinic in Kermanshah.
Methods: This case-control analytic study was carried out on 139 females with irritant contact dermatitis of hands and 102 female patients without any history of irritant contact dermatitis of hands. Obsessive compulsive disorder was determined based on the clinical interview using DSM-IV-TR (SCID) by a psychiatrist. Data analysis was performed using chi-square and z-test.
Results: The mean age in the case group was 28.2±8.4 and in the control group was 28.4±6.3 years. Fifty-eight (41.7%) of hand dermatitis patients and 5 (4.9%) of control group had obsessive compulsive disorder (P<0.05). Obsessive compulsive disorder was seen in 29 and 14 patients with moderate and severe irritant contact dermatitis, respectively.
Conclusion: Obsessive compulsive disorder is common in irritant contact dermatitis of hands. Psychiatric evaluation in female patients with chronic irritant contact dermatitis of hands especially moderate and severe forms is suggested.
Nafiseh Esmaeili, Mansoureh Akhavan, Hossein Mortazavi, Abbas Karimi,
Volume 4, Issue 3 (9-2013)
Abstract
Background and Aim: Bullous pemphigoid is an acquired
autoimmune disease with subepidermal blisters commonly seen in the elderly over
60 years old. The exact survival rate of the patients with bullous pemphigoid
was not available in Iran. The aim of this study was to evaluate the risk
factors of 5-year mortality of bullous pemphigoid patients.
Methods: In this retrospective study, 66 bullous pemphigoid
patients referred to Razi hospital from 1986 to 2006 were studied. Age, sex,
consumed corticosteroid type, duration of hospitalization, and clinical form of
bullous pemphigoid, ESR and comorbidities were evaluated to determine the risk
factors associated with patients’ 5-year mortality rate.
Results: Forty-seven patients (71.2 %) had
5-year survival. The most common comorbidities were cardiovascular diseases
(28.8%), diabetes (15%) and chronic respiratory diseases (9%). There was a significant
relationship between the age and the 5-year survival rate, in other words
patients aged over 70 years had a less 5-year survival rate (P<0.001). There was no statistically
significant association with gender, the type of corticosteroid, the disease clinical
forms, duration of hospitalization or ESR and 5-year survival (P>0.05).
Conclusion: The current study found a
significant relationship between the age of the patients and 5-year survival. Larger
studies considering more potential risk factors and more appropriate designs
might help to estimate the survival rate of patients with bullous pemphigoid
more precisely.
Ahmad Alipour, Zare Hossein, Emadi Seyyed Naser, Abdollahzade Hassan,
Volume 4, Issue 4 (12-2013)
Abstract
Background and Aim: Psoriasis is a chronic disease that causes deformity and disability in patients. There is little information about the impact of psychological interventions upon this disease. The purpose of this study was to evaluate the impact of group cognitive behavioral therapy upon physical factors such as severity and level of disease and extent of itching, and mental health of psoriasis patients.
Methods: This research was conducted as a semi-experimental study using pre-test and post-test with a control group and the follow-up period. Twenty Psoriasis patients were allocated into experimental and control groups. The group cognitive behavioral therapy was administered to 10 psoriasis patients allocated into the experimental group for 12 sessions. The members of both groups filled in the Psoriasis Area Severity Index (PASI) for the assessment of severity of psoriasis, general health questionnaire (GHQ), and the Quality of life in patients with pruritus (ItchyQoL) questionnaires.
Results: The results indicated that the group cognitive-behavioral therapy did not have any impact upon the improvement of physical symptoms (severity and level of disease and extent of itching), but it was effective on improving the patients' psychological status. Cognitive behavioral therapy has improved the patients' general health. There is a significant difference between the two groups in terms of multiple covariance analysis for different aspects of general health, including anxiety and insomnia (effect size 0.45 and P=0.004), depression (effect size: 0.25 and P=0.044), physical symptoms (effect size 0.28 and P=0.033), and social functioning (effect size 0.41 and P=0.003).
Conclusion: Although, based on the results, the group cognitive behavioral therapy does not directly affect reduction of physical symptoms of psoriasis the effectiveness of this method on patients' psychological symptoms is considerable as a mediator in the onset, exacerbation, and relapse of the disease.
Mohammad Ebrahimzadeh, Hossein Hajhosseini, Farideh Dehghani, Parichehr Kafaie, Davoud Dehghani Ashkezari,
Volume 4, Issue 4 (12-2013)
Abstract
Background and Aim: Hirsutism is one of the most common reasons for which women visit dermatology and beauty clinics. Lasers have got considerable popularity during last two decades because they can reduce unwanted hairs. This study was conducted to evaluate the satisfaction of patients with hirsutism traeted with diode laser, IPL or combination of both.
Methods: In this retrospective study, hirsute patients referred to Yazd Laser Center from October 2011 until October 2012 were studied. Patient satisfaction from the amount of hair loss one month after starting treatment, one month after the end of treatment and 6 months after treatment were asked using telephone.
Results: Patient satisfaction one month after the end of the treatment with diode laser was higher than the other two methods (P=0.034). Patient satisfactions at one month after initiation of the treatment and six months after the end of the treatment were not the statistically significant. The number of laser sessions was similar in the three groups.
Conclusion: Results of the current study revealed that there was no significant difference in the patient satisfaction with diode laser, IPL and combination of both methods in the treatment of hirsutism 6 months after the end of the treatment.
Ali Ebrahimi, Hossein Ershadinia,
Volume 5, Issue 1 (Volume 5, Number 1 2014)
Abstract
Background and Aim: Unwanted hair growth (hirsutism) is a cosmetic problem, which has been resulted in a large number of researches regarding its treatment. Patient satisfaction after treatment using hair removal lasers has been different. The aim of this study was to investigate the satisfactaion rates of the patients with hirsutism after being treated with a diode laser.
Methods: In this study satisfaction rates of 50 women with hirsutism were evaluated based on an audio-visual evaluation in Haj Daii clinic in Kermanshah, Iran.
Results: Fifty patients with a maen±standard deviation age of 32.5±9.2 years were categorized in three groups in accordance with their skin phototypes. Patient satisfaction after using laser diode hair removal with 25-40 J/cm2 was 74.6%. The most common side effect was transient post laser erythema (28.3%). The highest satisfaction rate was obtained in patients who were taking hormone regulating drugs (85.0%). The lowest satisfaction was obtained in patients with irregular menstrual cycle who were not taking any hormon drugs (73.3%). There was a direct correlation between the number of laser sessions and patients satisfaction (r=0.51, P<0.05).
Conclusion: Findings of the present study showed that diode laser is an effective method in treatment of hirsute patients and patients satisfaction rates are good.
Hossein Mortazavi, Farid Abbasi, Maryam Koopaie, Nafise Esmaeili,
Volume 5, Issue 2 (Volume 5, Number 2 2014)
Abstract
Background and Aim: Pemphigus vulgaris (PV) is the most common bullous autoimmune disease, which can cause mortality and morbidity in the patients who suffer from it. Researches to find reliable noninvasive laboratory tests to diagnose and monitor PV patients are being conducted.The aim of this study is to find the sensitivity of serum and salivary anti-DSG1 and anti-DSG3 antibodies in the diagnosis of PV by ELISA and to compare the results of serum and salivary autoantibodies with each other.
Methods: In this case-control study, 40 newly diagnosed patients with PV were recruited. Forty healthy controls were also recruited to this study. The clinical diagnosis of PV was confirmed by histopathology and direct immunofluorescence (DIF). Demographic data, disease severity and phenotypes were recorded on the questionnaires, which were developed for this study. DSG1 and DSG3 ELISA test were performed on serum and salivary samples of patients and controls.
Results: The mean±standard deviation age of patients, 43.37±11.94, with a range of 26 to 71 years. The sensitivities of serum anti-DSG3 and anti-DSG1 were 85% (34 cases had positive test results) and 90%, (36 cases had positive test results) respectively. The sensitivities of salivary anti-DSG3 and anti-DSG1 antibodies were accordingly 42.5% (17 cases had positive test results) and 60%, (24 cases had positive test results) respectively.
Conclusion: While the sensitivities of serum ELISA in detection of anti-DSG1 and anti-DSG3 were significantly higher than those of salivary ELISA, since the levels of the latter are chnaging in parallel to those of serum ELISA, they might be used to monitor the disease activity.
Azita Nikoo, Babak Hosseindoost, Alireza Khatami,
Volume 6, Issue 1 (Volume 6, Number 1 2015)
Abstract
Background and Aim: Mycosis fungoides (MF) is the most common primary cutaneous lymphoma. Diagnosis of early MF (eMF) is often difficult due to its resemblance of benign dermatoses. The aim of this study was to evaluate the role of provided clinical information on the histopathology request forms for diagnosis of eMF according to the International Society of Cutaneous Lympoma (ISCL) criteria.
Methods: In this cross-sectional study, 108 patients admitted to Razi Hospital, Tehran, between April 2012 and November 2013, who were biopsied as eMF cases, were recruited. Based on partial application of ISCL algorithm, the checklist of clinical and histopathological findings were scored.
Results: Eighty-five (78.7%) patients received maximum total clinical and histopathological scores (4) and their eMF were definitely diagnosed. Sixteen (14.8%) patients received a total score of 3, and suggestive eMF diagnosis was made. Further work up such as immunohistochemistry (IHC) evaluation were recommended. Seven patients (6.5%) received a total score of 2, which did not confirm eMF diagnosis. Follow up was recommended. In 14 (87.5%) of 16 patients who had received a total score of 3, the definite diagnosis of eMF was made according to the results of IHC. They were referred to receive treatment. In 2 patients (12.5%) diagnosis of eMF were not confirmed by IHC. They were recommended to undergo polymerase chain reaction (PCR) evaluation
Conclusion: Many MF cases can be diagnosed in the early stages using a combination of clinical and histopathological criteria.
Zeinab Ghasemi, Mehraban Falahati, Farideh Zaini, Gholam Hossein Ghaffarpour, Farzaneh Ahmadi, Seyed Ebrahim Eskandari,
Volume 6, Issue 2 (Volume 6, Number 2 2015)
Abstract
Background and Aim: Tinea unguium is a common disease with worldwide distribution most commonly seen in adult patients. Trichophyton rubrum and T. interdigital are the most common causes. The aim of this study was to investigate the frequency of tinea unguium causative agents in a referral dermatology hospital in Tehran, Iran.
Methods: This cross sectional study was conducted in 2010 and 2011 on clinically suspicious patients for tinea unguium referred to the Mycology Laboratory, Razi Hospital, Tehran, Iran. Samples from 700 patients were examined using direct smear microscopy and culture. Direct microscopic examination of the specimens was carried out using 20% potassium hydroxide solution. The specimens were cultured on Sabourad dextrose agar culture media containing chloramphenicol and cyclohexamid (Scc). For identifying the species of dermatophytes, complementary tests were used. Frequencies and relative frequencies were demonstrated in tables and chi-square and Fisher's exact tests were used to investigate any association between the categorical variables.
Results: Of 700 dystrophic nail samples, 53 samples (7.6%) were positive according to both direct examination and culture. Thirty-eight patients were males. The most common clinical type was distal subungual onychomycosis which was observed in 79.2% of cases. The most frequent detected dermatophyte species. was T. interdigital (39.6%) followed by T. rubrum (37.7%). Forty-seven patients had tinea unguium on their toe nails, 4 patients on their finger nails, and 2 patients had it on both finger and toe nails. Nineteen patients had underlying diseases, and the most common underlying disease was cardiovascular disease (26.3%).
Conclusion: Tinea unguium is a disease with worldwide distribution and identifying the causative agents and predisposing factors are necessary for better management of the patients.
Hamidreza Talari, Rezvan Talaee, Hossein Akbari, Narjes Sadat Kadkhodaee,
Volume 6, Issue 4 (Volume 6, Number 4 2016)
Abstract
Background and Aim: Androgenetic alopecia (AGA) is the most common cause of hair loss after puberty and its association with comorbid diseases including metabolic syndrome and cardiovascular diseases has become well known over the past two decades. The aim of this study was to evaluate the relationship between androgenetic alopecia with carotid artery intima media thickness as a marker for early diagnosis of atherosclerosis in women.
Methods: Fifty-four women, 27 with AGA and 27 healthy controls were enrolled in this case-control study. Demographic and clinical information of the patients were recorded in the predesigned questionnaires. Carotid intima media thickness was measured using ultrasound and the obtained data were recorded as well. Mann-Whitney and t tests were used to make comparisons between the two groups.
Results: The mean age of case and control groups were 28.8 ± 6.6 and 28.1 ± 6.7 years, respectively. No statistically significant association between AGA and carotid intima media thickness was found, although the findings showed an increase in carotid intima media thickness in patients (P>0.05) No statisctically significant association between carotid intima media thickness and the onset of disease, grade or pattern of AGA was found (P>0.05).
Conclusion: The results of this study did not show any statistically significant relationship between AGA and carotid intima media thickness. However, increased carotid intima media thickness in patients with AGA was found. Better designed studies with larger sample size are recommneded to evaluate carotid intima media thickness as a predictor for cardiovascular disease.
Azam Habibi, Mahmoud Nateghi Rostami, Masoumeh Douraghi, Masoumeh Dolati, Batool Hossein Rashidi, Roghaye Ahangari,
Volume 6, Issue 4 (Volume 6, Number 4 2016)
Abstract
Background and Aim: Trichomonas vaginalis infection is one of the most common sexually transmitted diseases of women and men in the world. To the best of our knowledge, there has been no previous report of the prevalence and complications of trichomoniasis in women of Qom.
Methods: In this cross-sectional study, the prevalence of T. vaginalis in women whom were admitted to a referral gynecology clinic in the city of Qom. For this purpose, two diagnostic methods, wet mount and ITS-PCR, were used to examin the vaginal swabs taken from the participants. Microscopic examination of cellular morphology and bacteria was also conducted on the stained smear.
Results: Three hundered volunteers were enrolled. Of 300 specimens, 7 (2.67%) by wet mount and 34 (11.3%) by ITS-PCR method were positive. The positive results of ITS-PCR were confirmed by sequencing of PCR products. In comparison with women without T. vaginalis infection, infection with T. vaginalis was associated with increased the risks of low birth weight (OR=43.3; 95% CI=2.8-671.9), in women with history of abortion (OR=91.8; 95% CI=15.5-544.2), and in women with premature rupture of membrane (PROM) (OR=21.6; 95% CI=2.1-22.9). Probability of finding of epithelial cells (OR=36.9; 95% CI=6.9-197.3) and white blood cells (OR=43.3; 95% CI=2.8-665.1) in stained smear were higher in women with T. vaginalis compared to those without T. vaginalis.
Conclusion: Comparing with wet mount, ITS-PCR seems to be a more sensitive and reliable technique in detection of T. vaginalis infection in women. The high prevalence of trichomoniasis emphasizes the need for screening of women in Qom. Early examination and accurate diagnosis of T. vaginalis, especially in middle-aged women, could prevent pregnancy-related complications of T. vaginalis.
Hossein Kavoussi, Ali Ebrahimi, Kiarash Amini, Mansour Rezaei, Neda Omidi,
Volume 7, Issue 1 (Volume 7, Number 1 2016)
Abstract
Background and Aim: Internal evaluation is one of the most effective educational assessment processes. Due to involvement of all educational department stake-holders, this evaluation has high efficacy and enforcement. Appropriate use of the findings of such evaluations improve educational quality. The aim of this study was to evaluate various aspects of education, research and facilities at the Department of Dermatology, Kermanshah University of Medical Sciences, Iran.
Methods: In this cross-sectional study, objectives, organizational status, management and authority, faculty members, students, teaching-learning strategies, educational equipments, theses and sabbaticals, and graduates of the Department of Dermatology, Kermanshah University of Medical Sciences were evaluated. Questionnaires were designed, and obtained data were analyzed by IBM SPSS Statistics (IBM Corp., Armonk, NY, USA) version 22.
Results: Most of evaluated components were satisfying. Learning-teaching strategy was the most satisfying factor with an average satisfaction rate of 87.5%, and the graduates issues was the least satisfying factor with an average satisfaction rate of 66.7%.
Conclusion: Planning and proceedings at the department and medical school levels according to feedbacks based on the results of this study not only could improve educational quality at the department, but also may help obtaining approval for initiating a dermatology residency program.
Amir Houshang Ehsani, Hossein Mortazavi, Pedram Noormohammadpour, Arghavan Azizpour, Sara Rostami, Maryam Nasimi,
Volume 7, Issue 2 (Volume 7, Number 2 2016)
Abstract
Background and Aim: Acne vulgaris is a common skin disorder. This study was conducted to evaluate the impact of Ramadan fasting on acne healing in patients admitted to the dermatology clinic, Razi Hospital, Tehran.
Methods: In this prospective cohort study, 10 fasting persons (9 women and 1 man) and 10 non-fasting persons (9 women and 1 man) with acne were studied. Their baseline acne severities were recorded and acne improvement was evaluated in both groups after Ramadan month.
Results: Acne improvement was 71% in fasting persons and 49% in non-fasting persons. Improvement in fasting persons i.e. was 1.4 times of non-fasting ones (P=0.158). However, no significant statistical difference was detected. Also, it was determined that improvement was different according to acne grading. Improvement in acne lesions in patients with grade 2 severity was 100%, in those with grade 3 acne was 78%, and in patients with grade 4 acne was 35 % (P=0.025). But in non-fasting patients there was not a statistical difference between acne severity and improvement rate. Furthermore in patients younger than 24, improvement rate of acne was 1.6 fold more than non-fasting persons and in patients older than 24, this ratio was 1.3 (P=0.011).
Conclusion: This study did not show any statistically significant difference in acne improvement between who were fasting and who were not during Ramadan. Studies with larger sample size are recommended.
Mohsen Sheykhhasan, Hossein Bakhtiari Pak, Mahdieh Ghiasi,
Volume 7, Issue 3 (Volume 7, Number 3 2016)
Abstract
Platelet-rich plasma (PRP) is a solution derived from whole blood that is enriched in the platelet fraction. Platelets serve as a reservoir of growth factors and cytokines. When platelets are activated in vivo, signaling molecules are released into the immediate microenvironment and activate receptors for various pathways. PRP has been applied to bedsores to promote healing. Over the last decade, it has been used as a valuable therapeutic method in various specialties such as maxillofacial surgery, plastic surgery, orthopedics and sports medicine. Only recently has PRP been utilized for dermatologic purposes, psrticularly, for the treatment of male and female pattern hair loss.
In this review, we discuss molecular and cellular pathways up-regulated by PRP important in hair folliculogenesis, and examine clinical evidence from all previously published studies involving the use of PRP for pattern hair loss.
Adele Kavehzadeh, Sara Beigrezaei, Mohammad Ali Nilforoushzadeh, Asieh Heidari, Sayed Mohsen Hosseini,
Volume 7, Issue 4 (Volume 7, Number 4 2017)
Abstract
Background and Aim: The present world is a world of short-sectional relationships, most people identify themselves by acknowledging their appearance instead of considering their inherited or acquired different characteristics. In this study, we decided to compare the body image between patients with skin diseases and healthy participants.
Methods: In this case-control study, 300 (150 cases and 150 controls) individuals aged from 18 to 64 years were selected in the Isfahan city. Satisfaction with body image and feelings of respondents regarding their apparent looks in different situations and different conditions were investigated using an a researcher-constructed questionnaire. To analyze the collected data, we used the analysis of covariance and compared the means.
Results: Single, younger, and less educated women had body image scores higher and more positive look to their bodies. Healthy people had higher score of body image than the patients with skin diseases. There was no significant relationship between gender and body image scores.
Conclusion: Skin diseases had an important role in body image. So we suggest that the effect of other diseases, that somehow affect the appearance of people on body image, be examined deeply for each disease.
Foroughossadat Ghasemzadeh, Kobra Etminani, Ali Arab-Kheradmand, Seyed Benyamin Hosseini Moini, ,
Volume 8, Issue 1 (Volume 8, Number 1 2017)
Abstract
Background and Aim: Non-Melanoma Skin Cancer (NMSC), including squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) is the most common cancer in Iran. This study aimed to infer implicit information in the cases of NMSC patients referred to the Cancer Institute of Tehran.
Methods: A number of 865 cases of NMSC related to 2007-2015 years were selected from the archives of Cancer Institute using simple random sampling method. Initially, epidemiological variables, were extracted and after preprocessing of the data, descriptive statistics were used to classify and graphic display of information.
Results: The mean age for patients was identified 65 years and the highest and lowest numbers of cases were in age groups of 69-60 and 19-10 years respectively. The incidence of SCC was higher than BCC in the first four age decades and this trend was reversed in the next decades. About 56% of cases were BCC and 44% were SCC and frequency of NMSC in men was 2/33 times more than women. The head/neck and trunk were the highest and lowest involved positions. The disease had relapsed at least twice in 32% of cases. The disease history showed that most of patients were previously affected by kinds of cancers, cardiovascular or metabolic diseases. The occupation of 114 patients was found to be as high-risk jobs. Most patients were referred to Cancer Institute from northern and western parts of the country.
Conclusion: Along with other studies, we found more cases of BCC than SCC, involvement of patients over 60 years at the head-neck and a previous history of cancer. But against other studies, SCC cases was found more in the first four decades of life than BCC cases, feet affected twice than hands and the locality of most cases was found in high latitudes. Patient records are potential resources that can help management of the diseases.
Kamand Hedayat, Saman Ahmad Nasrollahi, Hossein Rastegar, Fatemeh Zolfaghari, Alireza Firooz,
Volume 8, Issue 4 (Volume 8, Number 4 2018)
Abstract
Application of sunscreens is one of the most important ways for skin protection against sunburn, early skin aging and skin cancer.
Due to variety of sunscreen products, it is necessary to assure their protection ability against the sun’s damages. Performance assessment of sunscreens against UVB expressed by sun protection factor. Due to great cost of determination methods of this factor in foreign countries, developing a comprehensive protocol for in vivo SPF determination in Iran would have distinct benefits.
In this study four international standards have been reviewed and compared for Sun Protection Factor (SPF) determination including ISO24444, FDA2011, AS/NZS 2604:2012 and CEN 2006. The general process of in vivo SPF determination is similar in these protocols but there are some obvious differences in details that leading to advantages and disadvantages for each of them.
In this study a complete document were collected, then regarding to available facilities and with cooperation of Iran food and drug organization a comprehensive in vivo SPF determination protocol will be developed.
Kamand Hedayat, Saman Ahmad Nasrollahi, Hossein Rastegar, Fatemeh Zolfaghari, ,
Volume 9, Issue 1 (2018, Volume 9, Number 1 2018)
Abstract
Sunscreen products are among the most important ways for skin protection against sunburn, early skin aging and skin cancer. Due to existing wide variation of sunscreens, it is necessary to assure their protection ability against the sun damage. Performance assessment of sunscreen products against UVA is expressed by sun UVA protection factor (UVA-PF). Because currently these factors are determined in foreign countries at high cost, developing a comprehensive protocol for UVA-PF determination in Iran would have distinct benefits.
The two standards, CEN 2006 and FDA 2007, introduce persistent pigment darkening (PPD) method for UVA-PF in vivo determination, while following the same principles are different in details. For in vitro UVA-PF determination, 4 standards CEN 2006, FDA 2007, FDA 2011 and ISO 24443 provided protocols, which two of them (CEN 2006 and FDA 2011) proposed critical wavelength method. On the other side, FDA 2007 offered modified Diffey method. ISO 24443 approved that and considering in vitro UVA-PF determination correlated with PPD method.
In this review, complete documents were collected, and the available facilities and setups, with cooperation of Iran Center for Food and Drug Control Labs, a comprehensive UVA-PF determination protocol for Iranian sunscreen products was developed.
Siamak Kazemi Darabadi, Seyed Hossein Jarolmasjed, Danial Moshtagh,
Volume 9, Issue 3 (2018, Volume 9, Number 3 2018)
Abstract
Background and Aim: Burns are among the most common causes of wounds. One of the medications used in these cases is silver sulfadiazine 1%, which has many side effects. Therefore, people turn to traditional compounds for treatment of these ulcers . Despite the widespread use of lime water in combination with olive oil and Ziziphus in Iran, little research has been done to prove their benefits. The purpose of this study was to investigate the topical effect of Ziziphus and olive oil and lime water combination on the healing rate of third-degree burns in mice.
Methods: In this study, 24 male Balb/c mice with a mean weight of 25±5 g were used. After anesthesia, a 1 cm2 third-degree burn was created with a special device. The mice were randomly divided into four groups and received normal saline, Ziziphus poultice, olive oil-lime water, or silver sulfadiazine 1% daily. Pictures were taken weekly for three weeks. Then the area of the wounds was measured and the percentage of healing was calculated. Repeated measure ANOVA was used to analyze the data.
Results: In all weeks, the percentage of wound healing in the second to fourth groups was significantly higher than that of the first group, but was not significantly different from each other.
Conclusion: The results of this study showed the positive effect of Ziziphus leaves and the combination of olive oil and lime water on the healing rate of third-degree burn wounds in mice.
Abdoulhossein Emami Sigaroodi, Zeynab Haghdoost, Mohammad Taghi Moghadamnia, Ehsan Kazemnezhad Leyli,
Volume 9, Issue 4 (2018, Volume 9, Number 4 2019)
Abstract
Background and Aim: Burn is a risk, which threatens human beings every day in various forms. It is one of the most destructive injuries, associated with various physical and psychological complications. Burn affects the quality of life and life satisfaction . Evaluation of life satisfaction is very important due to its close relationship with physical and mental health. Given the high prevalence of burn in Iran and the presence of challenges in the treatment and rehabilitation of these patients, we decided to conduct this research to evaluate the life satisfaction in burned patients, admitted to Burn Injuries and Reconstructive Surgery Center in Rasht.
Methods: In this descriptive-analytical research, 379 burned patients were included in the study using convenient sampling method. The Diner Life Satisfaction Questionnaire was used to collect the data. Data were analyzed using descriptive and analytical statistics. The significance level was considered to be less than 0.05.
Results: Most of the subjects were male (64.1%) and had high level of education (34.6%). Also, most of them returned to their previous jobs (83.4%). Most of patients (48.5%) were satisfied with their life and the variables of lodging (P<0.0001), educational level (P<0.0001), marital status after burn (P=0.05), pre-burn job (P=0.016), post-burn job (P=0.014), skin graft (P<0.0001) and insurance (P<0.0001) were considered as predictive variables related to life satisfaction.
Conclusion: Since burn injury was expected to cause more than obtained dissatisfaction , other factors such as the power of faith and satisfaction with divine providence, high life expectancy, etc may influence their state of satisfaction. Thus, it is recommended that supporting and charity institutions (such as welfare, relief committee, IRIB, etc.) provide more support for these patients. It is also recommended that programs and classes with advisory and educational content be held for patients and their families.
