Seyedmohsen Mohebi Nodez, Alireza Zare Karizi, Bita Ghaderi, Shahrazad Aghababaei, Ismaeil Alizadeh,
Volume 15, Issue 3 (11-2024)
Abstract
Background: Scorpions are known as one of the oldest venomous animals on the planet. Scorpion bites are an important public health problem in many parts of the world, including Iran.
Case Report: In this paper, a 49-year-old woman is presented who came to the hospital with a complaining of skin reactions in the thigh area. The clinical findings in this study showed that the scorpion bite site had inflammatory reactions and redness after 24 hours. The patient was treated with Pentavalent anti-scorpion serum by intravenous injection. Approximately one week after the scorpion bite, the local and systemic symptoms disappeared with the use of anti-inflammatory ointments. Immediately after the scorpion bite, the patient's resting place was checked by the companions, and a specimen of the Hottentotta jayakari scorpion species was identified.
Conclusion: Considering that there are scorpion bite in Iran, in order to prevent and control them, it is necessary to increase the general awareness and knowledge of people at risk in society in order to reduce possible risks. In addition to these, increasing the awareness among doctors, especially dermatologists, of the skin symptoms of this dangerous animal, as therapists, can help speed up the treatment process.
Mahsa Fattahi,
Volume 16, Issue 3 (11-2025)
Abstract
Background: Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by defects in the NADPH oxidase complex, predisposing patients to severe bacterial and fungal infections. Dermatophytosis with severe inflammatory presentations such as tinea capitis is uncommon but challenging to manage in these patients.
Case presentation: We report a 9-year-old Iranian girl with autosomal recessive CGD who presented with refractory inflammatory scalp lesions. Mycological examination confirmed tinea capitis caused by Microsporum canis. Antifungal susceptibility testing showed reduced susceptibility to itraconazole, while susceptibility to terbinafine and fluconazole was preserved. Due to limited access to terbinafine, the patient received alternative management including antibacterial and anti-tuberculosis therapy, leading to clinical improvement.
Conclusion: This case highlights the diagnostic and therapeutic challenges of dermatophytosis in CGD patients and emphasizes the importance of accurate mycological diagnosis, antifungal susceptibility testing, and individualized multidisciplinary management, particularly in resource-limited settings.
