Showing 22 results for Medicine
Alireza Khatami,
Volume 3, Issue 4 (12-2012)
Abstract
According to evidence-based medicine, randomized controlled clinical trials are a group of research designs which provides the highest level of clinical evidence, particularly regarding therapeutic or preventive interventions. Considering the dramatic increase in the number of published clinical trials in medical journals, the readership need to have knowledge about the problems that may occur during design and conduct of these studies, as well as about proper reporting of them. Due to importance of these studies in clinical medicine, several guidelines have been developed regarding designing, conducting and reporting clinical trials. One of the most important guidelines which has been developed to alleviate the problems in reporting randomized clinical trials is Consolidated Standards for Reporting Trials (CONSORT). In this article, some crucial points with regards to the report of the comparison of outcomes of interventions in randomized controlled trials will be reviewed briefly.
Zohreh Bakhtiyari, Msc, Mohammadreza Radan, Md,
Volume 4, Issue 2 (6-2013)
Abstract
Skin is one of the most sensitive parts of the body and is important to maintain the beauty of man. Herbal products have fewer side effects than chemicals and have pharmacological effects on the skin, so are used in cosmetic preparations.
Books, articles and electronic databases including ISI Web of Science, PubMed, Magiran and IranMedex were searched to identify plants with positive effects on the skin, regardless of adverse effects and their interactions.
A number of plants which were used in the treatment of skin diseases and their effects had been established, were chosen and reviewed. Avocado, thyme, aloe vera, chamomile, almond, licorice, calendula, olive and yarrow were included in this review.
There are many herbs that have a role in the prevention and treatment of skin diseases, and are used in either traditional medicine or the preparation of cosmetics. The effects of a number of them have been scientifically proved and this information for the production of cosmetic and pharmaceutical products can be used.
Hamed Mahdizadeh, Haleh Ayatollahi, Nafiseh Esmaeili, Kamkar Mehran Kamkar ,
Volume 4, Issue 3 (9-2013)
Abstract
It is more than a decade that teledermatology has been
considered as a potential substitute for the face to face visits. To evaluate
its quality, the reliability and accuracy of teledermatology diagnoses are
compared to those which are made in face to face visits. In this article, the
results of the studies which have compared the reliability and accuracy of
diagnoses had been made using teledermatology to the face to face visits were
reviewed.
Different resources, such as electronic databases and e-journals
were used to choose relevant articles related to teledermatology published
between 1997 and 2013, and their main focus was on the reliability and accuracy
of diagnoses in teledermatology compared to those in the face to face visits.
The reliability and accuracy of diagnoses in
teledermatology compared to those in the face to face visits was more than 60%.
Moreover, improving the reliability and accuracy depended on different factors,
such as image quality, clinical information, differential diagnoses,
consultation with other colleagues and gaining their secondary opinions.
It seems that providing adequate clinical information about
patients can help to improve the reliability and accuracy of diagnoses in
teledermatology. In this case, teledermatology can be used to provide
healthcare services for the distant areas and the poor.
Alireza Khatami,
Volume 6, Issue 1 (4-2015)
Abstract
David Lawrence Sackett, OC, MD, FRSC, FRCP was an American-Canadian physician, trialist, and teacher. He is best known as one of the pioneers of evidence-based medicine (EBM), which is arguably the most important movement in medicine over the past three decades. He founded the first clinical epidemiology department in McMaster University in Hamilton, Canada in 1967. In addition, he was the head of the Center for the Evidence-Based Medicine in Oxford, UK. He also was the first chair of Cochrane Collaboration and the first founding coeditor of the journal of Evidence-Based Medicine and had many other honors. He published 12 books, 60 chapters in other books, and about 300 articles in scientific and medical journals.
He died on May 13, 2015 at age 80 because of cholangiocarcinoma. While Dr. Sackett will be missed by his friends, colleagues, mentees as well as EBM proponents and followers all over the world, his contributions to EBM in particular, and to medicine in general will never be forgotten.
Alireza Khatami, Alireza Firooz,
Volume 6, Issue 3 (10-2015)
Abstract
Three decades have passed since the first time evidence-based medicine (EBM), in its current form, was introduced. Arguably, over the past two decades it has been the most significant movement in medicine. There is no need to emphasize any approach to clinical medicine practice, including EBM, has its proponents and opponents. Certainly, EBM has been subjected to many challenges and criticisms. Some of those challenges are basically related to misunderstanding and misinterpretations of EBM. However, there are some challenges that are real and are acknowledged by the most loyal EBM supporters. After hearing some criticisms posed by few knowledgeable and competent dermatologists during the recently held 7th Evidence-Based Dermatology (EBD) seminar in Tehran, the authors of this letter, two of the pioneers of EBD in Iran, decide to open a gate for sharing and discussing different viewpoints on EBM and EBD.
Alireza Khatami, Nooshin Rahnama,
Volume 7, Issue 2 (7-2016)
Abstract
About 25 years have been passed since the evidence-based medicine (EBM) group declared it as a new approach to teaching and practicing clinical medicine. EBM was based on the combination of three principles: use of current best evidence from research, clinical expertise, and patients' values and preferences. Practically, EBM substitutes pathophysiological reasoning based on basic science research with use of clinical evidence from high quality randomized controlled clinical trials. Like all other approaches to clinical medicine, EBM has been criticized since it was introduced. Herein, we review common problems of EBM according to its critics, introduce what is known as real EBM, and briefly discuss how we could move towards real EBM.
Alireza Khatami,
Volume 7, Issue 4 (1-2017)
Abstract
Fatemeh Fadaei, Ebrahim Khadem,
Volume 8, Issue 1 (4-2017)
Abstract
Iranian traditional medicine (ITM) scholars have explained the structure and function of each organ based on clinical observations and past experiences. The skin is especially important due to apparent clinical manifestations serving as a convenient diagnosis tool. This study was aimed to evaluate the anatomy and physiology of the skin as presented in ITM School and compare with conventional medicine. Relevant keywords were searched in ITM reference books, Google scholar, PubMed, and Scopus. After extracting the data, the results were classified in terms of concepts and tables.
ITM scholars believe the embryonic origin of skin is similar to nervous tissue. In their view, the skin has a moderate temperament, and is a combination of fibers, nerve ends, muscles and vessels. Among the most important functions of the skin is the sense of touch, body temperature regulation, and excretion of wastes.
In conventional medicine, the skin consists of epidermis, dermis, and hypodermis layers. The embryonic origin of epidermis is the ectoderm. Protection and body temperature regulation, sensory activities, gas exchange, absorption of ultraviolet rays and disposal of excess body electrolytes are considered as the most important skin functions.
Overview of fetal origin, structure and function of the skin between these two schools of medicine interpreted in many ways, revealed many similarities.
Elham Zareie, Roodabeh Bahramsoltani, Parisa Heidari, Leyla Shirbeigi,
Volume 8, Issue 2 (7-2017)
Abstract
Vitiligo is a common disorder in skin pigmentation and has an important role in patient’s quality of life. It may also cause severe emotional stress which makes its treatment necessary. As conventional therapeutic strategies are ineffective, there is an increasing tendency to use complementary medicine in the management of vitiligo. This article has been written with the aim of describing Iranian Traditional Medicine (ITM) approach to vitiligo mechanisms, prognosis and natural therapeutics. It is a product of a library study in the main ITM references and also related articles using mentioned keywords.
According to ITM text books human body consists of four substantial humors, each has a very specific quality and quantity. Any excess or deficit of these humors may result in different disorders. Changing in phlegm humor and also improper function of “expulsive faculty” are the main causes of vitiligo from the viewpoint of ITM.
Fateme Fadaei, Ensieh Arefi, Ebrahim Khadem,
Volume 8, Issue 4 (1-2018)
Abstract
The skin is the largest organ of the human body, the first protective barrier of the body and one of the important excretory organs. In conventional medicine, there is great focus on skin rashes to help to diagnose the internal illnesses. Persian medical scholars have also studied a wide range of internal disorders by examining skin manifestations. The aim of this study is to investigate the etiology and semiology of various skin rashes and manifestations from Persian and conventional medicine viewpoints, and to clarify similarities and differences between them. For this purpose data corresponding with key words was extracted from reference books and then relevant scientific databases including Google scholar, PubMed, Web of Science, Scopus and reliable sources like Janquira histology, Habif and Savin's dermatology books were examined. An overview of the cutaneous rash and diseases, revealed that in many cases, these two schools of medicine are not comparable. However, in some cases, such as etiology, description, clinical signs, diagnosis, etc., serious similarities in topic of rashes, skin manifestations and chronic diseases are mentioned in the overview of this two medical schools.
Seyed Majid Ghazanfari, Maliheh Motevaselian, Roshanak Salari,
Volume 9, Issue 1 (4-2018)
Abstract
Itching is a mental feeling that elicits desire to scratch and results from stimulation of itch, pain or palpation receptors in the skin. In Iranian medicine, itching is referred as hekka. Several factors can cause this symptom. Various drugs are used to treat itching. They are sometimes costly and not readily available and have side effects. Given the time-consuming and cost-effective processes for the discovery of effective drugs, new strategies are needed to reduce processes time and costs. One of these strategies could be the use of previous experiences on medicinal plants and spices used in traditional medicine schools.
In this review, we searched the keyword "itching, pruritus" in three reference books of pharmacology of Iranian medicine, including The Canon of Medicine (Al-Qanon fi al-Tibb), Tohfe Momenin, and Makhzan- Al' Advieh and ened up with a list of 60 multifaceted plants effective in improvement of pruritus. The efficacy of each of them was categorized based of available evidence. Therefore, it is recommended to use the rich experience of Iranian traditional medicine in the production of new drugs for pruritus.
Seyede Zahra Emami Razavi, Maryam Hoseini, Mohaddeseh Azadvari,
Volume 9, Issue 3 (10-2018)
Abstract
Notalgia paresthetica (NP) is a neuropathic complication which occurs within the innervating field of T2-T6 spinal nerves. The patient complains of burning and itching sensation in the lower part of the inner margin of the scapula, and because of frequent itching,signs of skinscratching and hyperpigmentation are observed in the affected area. The definite cause of this pathology is unclear. Available resources have suggested the followings as the possible causes of the disorder: entrapment of the sensory branches within surrounding muscles, postural abnormalities such as scoliosis and kyphosis and degenerative changes of the spine. NP is usually represented as a rare pathology, however, the relatively common clinical incidence suggests a lack of attention to appropriateidentification, diagnosis and treatment ofthe patients. Diagnosis is done through history taking and physical examination, and there is often no need to
additional studiesfor confirmation. A wide spectrum of treatment options have been recommended. Although there is often a tendency to prescribe topical and oral medications for treatment of NP, but application of non-pharmacological therapies such as therapeutic exercises to correct abnormal postures, physical agent modalities such as electrical stimulation and also acupuncture can be effective in accelerating the treatment process and increasing the duration of recovery. Given the undeniable importance of the disorder and its impact on patient's quality of life, a comprehensive approach to existing treatment options with an emphasis on the role of physical medicine and rehabilitation specialists will be discussed in this paper.
Seyede Zahra Emami Razavi, Maryam Hoseini, Mohaddeseh Azadvari, Zahra Saffarian,
Volume 10, Issue 1 (4-2019)
Abstract
Acupuncture is an ancient medical procedure that is commonly used. It has been used in China for over two thousand years. Acupuncture has gained increasing interest from the public as well as health professionals for a wide range of disorders. This method works through regulation of qi current (life energy in body). Acupuncture has been introduced recently in dermatology for rejuvenation and treatment of facial wrinkles and improving muscle tone and elasticity. Acupuncture is used for treatment of many medical conditions including skin disorders. Tiny, sterile, needles are inserted along meridian lines and acupuncture points to increase blood circulation. Cosmetic acupuncture is a totally natural and holistic anti-ageing treatment that aims to reduce fine lines and wrinkles. Different mechanisms have been proposed for cosmetic acupuncture, including increasing muscle elasticity, and restoring muscle tone. There have been also evidence of increase in skin moisture and lipid.
In this method, body points and local facial points are used and usually 10-12 sessions of facial acupunctures are recommended. With the increasing popularity of complementary therapies in the community, acupuncture is also considered as a new therapeutic approach.
Seyedmajid Ghazanfari, Jamshid Jamali, Azadeh Saki, Mohammadreza Noras, Roshanak Salari, Ali Khorsand Vakilzade, Farzane Sharifipour,
Volume 10, Issue 3 (11-2019)
Abstract
Background and Aim: Pruritus is one of the most common problems of chronic kidney diseases. Different treatment modalities, while extending the life span of patients, can lead to changes in their lifestyle, health status and ultimately change their quality of life (QOL). Understanding the different aspects of patients' QOL leads to better services provided by health care teams to improve the patients' QOL. The aim of this study was to evaluate the quality of life of hemodialysis patients with uremic pruritus in Mashhad in 1396 with a view to Iranian Medicine.
Methods: This descriptive-analytical study was performed on 52 patients. Data collection was done by the World Health Organization QOL and researcher-made demographic Questionnaire and SPSS 16 software was used for data analysis.
Results: The mean age of patients was 51.73 years and mean duration of dialysis was 41.42 months. Total score of life quality was 56. The lowest and highest scores were seen in physical and environmental dimensions. There was an inverse significant relationship between some aspects of QOL with hemoglobin and creatinine and a direct significant relationship with age, diabetes, hypertension and hyperlipidemia (P<0.005).
Conclusion: Hemodialysis patients' QOL is lower than others and several factors can improve it. Special attention to the individual characteristics of hemodialysis patients can be helpful in predicting their basic needs.
Mohsen Haghir Ebrahimabadi, Ebrahim Khadem,
Volume 10, Issue 3 (11-2019)
Abstract
Urticaria is a relatively common skin disease characterized by red or white itchy and transient swellings. In more severe cases, it can reduce level of consciousness and be life-threatening due to swelling of tongue or throat and airway obstruction
In conventional medicine, this disease is treated symptomatic and mainly by antihistamines. Studies have indicated that urticaria is similar to "shara" (a type of skin disease mentioned in Persian medicine) in terms of etiology, description, clinical symptoms and diagnosis. In Persian medicine (Iranian traditional medicine) litrature, efficacy of several medicinal plants for the treatment of "shara" has been explaind.
This study is a review on the effective herbal remedies in the treatment of urticaria based on search in Iranian medicine resources, and conventional medicine litrature. Data were extracted from Iranian medicine textbooks and scientific databases including Google scholar, Pub Med, Web of Science and Scopus. It was found that Iranian medicine scholars have used 48 different medicinal plants to treat and reduce the complications of urticaria and the recent scientific studies have proven antiinflammatory, antioxidant and immune-regulating properties in 45 of these plants.
Roshanak Salari, Maliheh Motavasselian, Rahime Akrami, Seyedmajid Ghazanfari,
Volume 10, Issue 4 (1-2020)
Abstract
Pruritus is one of the most common problems that is seen separately or in combination with various diseases and has been studied in various medical schools. Its various aspects including definition, pathogenesis, types and treatments have been elaborated and tailored to the basics of each medical perspective. This study investigates the pruritus from modern and Persian medicine perspective.
This study is a library review focusing on the pruritus. Initially related keywords include pruritus, itching, hekka, hives and wheal was searched among the prestigious scientific and reference textbooks, journals and sites of modern and Persian medicine such as Rook's textbook of dermatology, Habif Clinical dermatology, Al-Qanun fi al-Tibb, Zakhireh Kharazmshahi, Teb-e-Akbari, Khulasah al-Hikmah, Kamel al-Sana'a al-Tebbiya, Exir-e A'zam, Tohfe Al-Momenin and Makhzan-al-Advie. Then the necessary material was collected and classified and finally the present article was compiled.
In both medical schools, the charecteristics and function of the skin are described initially, then the causes and mechanisms of pruritus are defined and explained. To facilitate understanding and presenting the subject, appropriate classificationare presented for each view. Also, for the pruritus treatment, appropriate recommendations have been put forward for each patient or condition.
Generally, there is not much difference between the two views, but modern medicine is going more specifically through details. While the Persian medicine discusses more comprehensively. The treatment basis in Persian medicine is based on different individual and environmental conditions.
Hamidreza Ahmadi Ashtiani, Alireza Firooz, Hossein Rastegar, Amirhosein Askaripour,
Volume 10, Issue 4 (1-2020)
Abstract
A wound is described as any laceration in normal anatomic structure and functional integrity of the skin. Chronic wounds don’t progress through the normal wound healing process in 3 months leaving open laceration of different degrees of severity. Diabetic wound healing is an insurmountable process due to the chronic nature of diabetic wounds. For these complications, this has been a challenge in the health care system. By the appearance of regenerative medicine, advisedly stem cell-based therapies and ingredients have been gained the focus of researchers and professionals as well. As there is no definite cure for diabetic wounds and forasmuch as the appearance of regenerative medicine and cell-based therapies there is a big hope to find a definite treatment for diabetic wounds. In this article novel therapies based on stem cells were observed.
Seyedalireza Golshani, Zahra Hosseinhashemi, Mohammadmahdi Zarshenas,
Volume 12, Issue 4 (2-2022)
Abstract
Khadab is one of the most important solutions used to beautify and strengthen hair, and Khadab has been used for a long time throughout history. Moreover, putting Khadab has been a long- lasting tradition in the course of history. Also, Iranian medical sources pointed out to the herbs used in Khadab and its role in human health. In this regard, the present study examines Khadab and its place in the history of Islamic civilization.
This is a desk study which is conducted through reviewing the main sources, Hadiths, and written sources of Iranian medicine. Also, various databases such as Magiran, SID, Google Scholar were searched to reach new findings. What is important in this study is putting Khadab during the course of history for adornment and human health. Moreover, diseases were cured through putting Khadab.
Putting Khadab and promoting this act can be effective in improving mental and physical health. Therefore, putting Khadab and its effect on the health of the human body and the herbs used in it need further investigation, as this research can be used to enhance the knowledge of the experts of traditional medicine.
Pedram Noormohammadpour, Amirhooshang Ehsani, Ifa Etesami, Amin Rahmani,
Volume 13, Issue 1 (5-2022)
Abstract
Background and Aim: Skin injuries with various causes may lead to legal action. Complaints are referred to specialized authorities such as Razi Hospital, before specialized forensic medicine commission comment. The present study surveyed demography of patients' complaints and initial diagnosis at the time of referral over a period of 6 months.
Methods: In this retrospective study, patients referred for initial visit, from Forensic Medicine Office in the September 2018-March 2019, were examined. The patients' complaints at the time of referral and the clinical diagnosis made at the initial examination were recorded.
Results: A total of 220 patients including 176 women (80%) and 44 men (20%) with a mean age of 34.8 years were included. 42 different complaints were documented, including traumatic hair loss with 91 cases (41.4%) - the most common - followed by complications of laser hair removal with 32 cases (14.6%) and filler injections with 16 cases (7.3%). Scarring from trauma, reaction to chemicals during work or accidental contact, rare injuries from various treatments, and even cases of pediculosis (contamination of the accommodation) or zoster (complaint about care in the treatment center), etc. were observed.
Conclusion: Traumatic hair loss (mainly due to fight) was the most common complaint. Knowing other cases may expand physicians' awareness regarding the wide range of complaints that can be raised and improve the process of some treatment measures.
Negar Asghari Hosori, Zeinab Bagheri,
Volume 15, Issue 2 (8-2024)
Abstract
The limitations of common needles in drug delivery, such as pain, infection, and side effects, have become a stimulus to search for more efficient alternatives. Meanwhile, microneedles have brought new hope in skin drug delivery. These microstructures are temporarily placed in the upper layers of the skin and provide a painless and non-invasive way for drugs to pass through the skin barrier. Diversity in the design and ingredients of microneedles allows the release of a wide range of drugs with high efficiency and low side effects. On the other hand, nanomedicines are proposed as an ideal alternative due to the limitations of traditional drugs and the need for more targeted and less detrimental options. Nanomedicines are new drug delivery systems that are designed and produced in nanometer dimensions. These small particles can carry and release drugs directly to the target cells with high precision and efficiency. By reducing side effects and increasing the effectiveness of treatment, nanomedicines can play a key role in improving the quality of treatment for various diseases. Considering the unique advantages of the combination of microneedles and nanomedicines, it is an important issue to investigate different strategies for using these new systems in drug release. In this article, this issue has been investigated as well as the applications of nanomedicine transfer by microneedle in the treatment of diseases and the upcoming challenges of this emerging technology.
